pol mutations conferring zidovudine and didanosine resistance with different effects in vitro yield multiply resistant human immunodeficiency virus type 1 isolates in vivo
about
Resistance to 2',3'-dideoxycytidine conferred by a mutation in codon 65 of the human immunodeficiency virus type 1 reverse transcriptase(Alkylamino) piperidine bis(heteroaryl)piperizine analogs are potent, broad-spectrum nonnucleoside reverse transcriptase inhibitors of drug-resistant isolates of human immunodeficiency virus type 1 (HIV-1) and select for drug-resistant variants of HIn vitro induction of human immunodeficiency virus type 1 variants resistant to 2'-beta-Fluoro-2',3'-dideoxyadenosineAn in vivo mutation from leucine to tryptophan at position 210 in human immunodeficiency virus type 1 reverse transcriptase contributes to high-level resistance to 3'-azido-3'-deoxythymidineHuman immunodeficiency virus type 1 reverse transcriptase genotype and drug susceptibility changes in infected individuals receiving dideoxyinosine monotherapy for 1 to 2 yearsRelationship between didanosine exposure and surrogate marker response in human immunodeficiency virus-infected outpatientsMultiple-drug-resistant mutants of feline immunodeficiency virus selected with 2',3'-dideoxyinosine alone and in combination with 3'-azido-3'-deoxythymidineDecreased processivity of human immunodeficiency virus type 1 reverse transcriptase (RT) containing didanosine-selected mutation Leu74Val: a comparative analysis of RT variants Leu74Val and lamivudine-selected Met184Val.Cross-clade inhibition of recombinant human immunodeficiency virus type 1 (HIV-1), HIV-2, and simian immunodeficiency virus SIVcpz reverse transcriptases by RNA pseudoknot aptamers.Enzymatic characterization of human immunodeficiency virus type 1 reverse transcriptase resistant to multiple 2',3'-dideoxynucleoside 5'-triphosphates.Diminished RNA primer usage associated with the L74V and M184V mutations in the reverse transcriptase of human immunodeficiency virus type 1 provides a possible mechanism for diminished viral replication capacity.Resistance to nucleoside analogs of selective mutants of human immunodeficiency virus type 2 reverse transcriptase.Effects of zidovudine-selected human immunodeficiency virus type 1 reverse transcriptase amino acid substitutions on processive DNA synthesis and viral replication.Alternating versus continuous drug regimens in combination chemotherapy of human immunodeficiency virus type 1 infection in vitro.Management of antiretroviral drug therapy in human immunodeficiency virus infection.Viral resistance patterns selected by antiretroviral drugs and their potential to guide treatment choice.The L74V mutation in human immunodeficiency virus type 1 reverse transcriptase counteracts enhanced excision of zidovudine monophosphate associated with thymidine analog resistance mutations.Zidovudine resistance mutations and human immunodeficiency virus type 1 DNA burden: longitudinal evaluation of six patients under treatment.
P2860
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P2860
pol mutations conferring zidovudine and didanosine resistance with different effects in vitro yield multiply resistant human immunodeficiency virus type 1 isolates in vivo
description
1993 nî lūn-bûn
@nan
1993 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1993 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
1993年の論文
@ja
1993年論文
@yue
1993年論文
@zh-hant
1993年論文
@zh-hk
1993年論文
@zh-mo
1993年論文
@zh-tw
1993年论文
@wuu
name
pol mutations conferring zidov ...... virus type 1 isolates in vivo
@ast
pol mutations conferring zidov ...... virus type 1 isolates in vivo
@en
pol mutations conferring zidov ...... virus type 1 isolates in vivo
@nl
type
label
pol mutations conferring zidov ...... virus type 1 isolates in vivo
@ast
pol mutations conferring zidov ...... virus type 1 isolates in vivo
@en
pol mutations conferring zidov ...... virus type 1 isolates in vivo
@nl
prefLabel
pol mutations conferring zidov ...... virus type 1 isolates in vivo
@ast
pol mutations conferring zidov ...... virus type 1 isolates in vivo
@en
pol mutations conferring zidov ...... virus type 1 isolates in vivo
@nl
P2093
P2860
P356
P1476
pol mutations conferring zidov ...... virus type 1 isolates in vivo
@en
P2093
A M Caliendo
H A Liebman
J C Kaplan
K M Devore
M S Hirsch
R T D'Aquila
P2860
P304
P356
10.1128/AAC.37.7.1480
P407
P577
1993-07-01T00:00:00Z