Dioxin induces localized, graded changes in chromatin structure: implications for Cyp1A1 gene transcription
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Overview of AHR functional domains and the classical AHR signaling pathway: induction of drug-metabolizing enzymesDioxin-induced CYP1A1 transcription in vivo: the aromatic hydrocarbon receptor mediates transactivation, enhancer-promoter communication, and changes in chromatin structureUnderstanding the human health effects of chemical mixtures.Cloning and characterization of HuR, a ubiquitously expressed Elav-like proteinDifferential recruitment of coactivator RIP140 by Ah and estrogen receptors. Absence of a role for LXXLL motifsInteractions between the aryl hydrocarbon receptor and P-TEFb. Sequential recruitment of transcription factors and differential phosphorylation of C-terminal domain of RNA polymerase II at cyp1a1 promoterThe Q-rich subdomain of the human Ah receptor transactivation domain is required for dioxin-mediated transcriptional activityGlucocorticoid receptor-glucocorticoid response element binding stimulates nucleosome disruption by the SWI/SNF complexCharacterization of the mouse Cyp1B1 gene. Identification of an enhancer region that directs aryl hydrocarbon receptor-mediated constitutive and induced expression.Tissue-specific chromatin structure of the phenobarbital-responsive unit and proximal promoter of CYP2B1/2 and modulation by phenobarbital.Differential regulation of the dioxin-induced Cyp1a1 and Cyp1b1 genes in mouse hepatoma and fibroblast cell lines.The 2001 Veylien Henderson Award of the Society of Toxicology of Canada. Positive and negative transcriptional regulation of cytochromes P450 by polycyclic aromatic hydrocarbons.The aromatic hydrocarbon receptor modulates the Hepa 1c1c7 cell cycle and differentiated state independently of dioxinTransactivation domains facilitate promoter occupancy for the dioxin-inducible CYP1A1 gene in vivo.Assaying chromatin structure and remodeling by restriction enzyme accessibility.Genome Editing of the CYP1A1 Locus in iPSCs as a Platform to Map AHR Expression throughout Human Development.Down-regulation of major histocompatibility complex Q1b gene expression by 2,3,7,8-tetrachlorodibenzo-p-dioxin.Roles of coactivator proteins in dioxin induction of CYP1A1 and CYP1B1 in human breast cancer cells.Hypoxia-inducible mammalian gene expression analyzed in vivo at a TATA-driven promoter and at an initiator-driven promoter.Chromatin context dominates estrogen regulation of pS2 gene expression.Chromatin changes on the GSTP1 promoter associated with its inactivation in prostate cancer.Human CYP1A1GFP expression in transgenic mice serves as a biomarker for environmental toxicant exposure.Functional involvement of the Brahma/SWI2-related gene 1 protein in cytochrome P4501A1 transcription mediated by the aryl hydrocarbon receptor complex.Analysis of the murine AhR gene promoter.Aryl hydrocarbon receptor-mediated signal transduction.Induction of drug-metabolizing enzymes by dioxin.Transcriptional activation of cytochrome P450 genes by different classes of chemical inducers.Mechanisms of ligand-induced aryl hydrocarbon receptor-mediated biochemical and toxic responses.Protein kinase C modulates regulation of the CYP1A1 gene by the aryl hydrocarbon receptor.
P2860
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P2860
Dioxin induces localized, graded changes in chromatin structure: implications for Cyp1A1 gene transcription
description
1995 nî lūn-bûn
@nan
1995 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
1995 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
1995年の論文
@ja
1995年論文
@yue
1995年論文
@zh-hant
1995年論文
@zh-hk
1995年論文
@zh-mo
1995年論文
@zh-tw
1995年论文
@wuu
name
Dioxin induces localized, grad ...... for Cyp1A1 gene transcription
@ast
Dioxin induces localized, grad ...... for Cyp1A1 gene transcription
@en
Dioxin induces localized, grad ...... for Cyp1A1 gene transcription
@nl
type
label
Dioxin induces localized, grad ...... for Cyp1A1 gene transcription
@ast
Dioxin induces localized, grad ...... for Cyp1A1 gene transcription
@en
Dioxin induces localized, grad ...... for Cyp1A1 gene transcription
@nl
prefLabel
Dioxin induces localized, grad ...... for Cyp1A1 gene transcription
@ast
Dioxin induces localized, grad ...... for Cyp1A1 gene transcription
@en
Dioxin induces localized, grad ...... for Cyp1A1 gene transcription
@nl
P2860
P356
P1476
Dioxin induces localized, grad ...... for Cyp1A1 gene transcription
@en
P2093
J P Whitlock
P2860
P304
P356
10.1128/MCB.15.7.3714
P407
P577
1995-07-01T00:00:00Z