Determination of tetrahydrothiophene formation as a probe of in vitro busulfan metabolism by human glutathione S-transferase A1-1: use of a highly sensitive gas chromatographic-mass spectrometric method

Determination of tetrahydrothiophene formation as a probe of in vitro busulfan metabolism by human glutathione S-transferase A1-1: use of a highly sensitive gas chromatographic-mass spectrometric method

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http://www.wikidata.org/entity/Q28370434
Cysteine S-conjugate β-lyases: important roles in the metabolism of naturally occurring sulfur and selenium-containing compounds, xenobiotics and anticancer agents.Reversible and irreversible protein glutathionylation: biological and clinical aspects.A comparison of reversible versus irreversible protein glutathionylation.Metabolism of the cysteine S-conjugate of busulfan involves a beta-lyase reaction.Dehydroalanine analog of glutathione: an electrophilic busulfan metabolite that binds to human glutathione S-transferase A1-1.Pharmacometabonomic Prediction of Busulfan Clearance in Hematopoetic Cell Transplant Recipients.Antineoplastic agent busulfan regulates a network of genes related to coagulation and fibrinolysis.Overexpression of glutathione S-transferase A1-1 in ECV 304 cells protects against busulfan mediated G2-arrest and induces tissue factor expression.The effect of modulation of glutathione cellular content on busulphan-induced cytotoxicity on hematopoietic cells in vitro and in vivo.N-acetyl-L-cysteine does not affect the pharmacokinetics or myelosuppressive effect of busulfan during conditioning prior to allogeneic stem cell transplantation.
P2860

Determination of tetrahydrothiophene formation as a probe of in vitro busulfan metabolism by human glutathione S-transferase A1-1: use of a highly sensitive gas chromatographic-mass spectrometric method

Item
http://www.wikidata.org/entity/Q28370434
description
1999 nî lūn-bûn
@nan
1999 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի հունիսին հրատարակված գիտական հոդված
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1999年の論文
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1999年論文
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1999年論文
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1999年論文
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1999年論文
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1999年論文
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1999年论文
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name
Determination of tetrahydrothi ...... phic-mass spectrometric method
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Determination of tetrahydrothi ...... phic-mass spectrometric method
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Determination of tetrahydrothi ...... phic-mass spectrometric method
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Determination of tetrahydrothi ...... phic-mass spectrometric method
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Determination of tetrahydrothi ...... phic-mass spectrometric method
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Determination of tetrahydrothi ...... phic-mass spectrometric method
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Determination of tetrahydrothi ...... phic-mass spectrometric method
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Determination of tetrahydrothi ...... phic-mass spectrometric method
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Determination of tetrahydrothi ...... phic-mass spectrometric method
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P2093
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Determination of tetrahydrothi ...... phic-mass spectrometric method
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10.1016/S0378-4347(99)00170-X
P407
P433
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