Binding of the antagonist [3H]candesartan to angiotensin II AT1 receptor-transfected [correction of tranfected] Chinese hamster ovary cells

Binding of the antagonist [3H]candesartan to angiotensin II AT1 receptor-transfected [correction of tranfected] Chinese hamster ovary cells

Item
http://www.wikidata.org/entity/Q28371751
Long-lasting target binding and rebinding as mechanisms to prolong in vivo drug actionAngiotensin II dose-effect curves and Schild regression plots for characterization of different angiotensin II AT1 receptor antagonists in clinical pharmacology.Exploring avidity: understanding the potential gains in functional affinity and target residence time of bivalent and heterobivalent ligands.On the different experimental manifestations of two-state 'induced-fit' binding of drugs to their cellular targetsCell membranes… and how long drugs may exert beneficial pharmacological activity in vivoThe Pharmacogenomic and Metabolomic Predictors of ACE Inhibitor and Angiotensin II Receptor Blocker Effectiveness and Safety.Translocation of the insulin-regulated aminopeptidase to the cell surface: detection by radioligand binding.'Partial' competition of heterobivalent ligand binding may be mistaken for allosteric interactions: a comparison of different target interaction models.Molecular mechanisms for the persistent bronchodilatory effect of the beta 2-adrenoceptor agonist salmeterolEstimation of the dissociation rate of unlabelled ligand-receptor complexes by a 'two-step' competition binding approach.Molecular characterisation of the interactions between olmesartan and telmisartan and the human angiotensin II AT1 receptor.Effects of target binding kinetics on in vivo drug efficacy: koff , kon and rebinding.Distinct in vivo target occupancy by bivalent- and induced-fit-like binding drugs.Link between a high for drug binding and a fast clinical action: to be or not to be?
P2860

Binding of the antagonist [3H]candesartan to angiotensin II AT1 receptor-transfected [correction of tranfected] Chinese hamster ovary cells

Item
http://www.wikidata.org/entity/Q28371751
description
1999 nî lūn-bûn
@nan
1999 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Binding of the antagonist [3H] ...... d] Chinese hamster ovary cells
@ast
Binding of the antagonist [3H] ...... d] Chinese hamster ovary cells
@en
Binding of the antagonist [3H] ...... d] Chinese hamster ovary cells
@nl
type
label
Binding of the antagonist [3H] ...... d] Chinese hamster ovary cells
@ast
Binding of the antagonist [3H] ...... d] Chinese hamster ovary cells
@en
Binding of the antagonist [3H] ...... d] Chinese hamster ovary cells
@nl
prefLabel
Binding of the antagonist [3H] ...... d] Chinese hamster ovary cells
@ast
Binding of the antagonist [3H] ...... d] Chinese hamster ovary cells
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Binding of the antagonist [3H] ...... d] Chinese hamster ovary cells
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P1433
P1476
P2093
P304
P31
P407
P433
P478
P577
P698
P1433
P1476
Binding of the antagonist [3H] ...... d] Chinese hamster ovary cells
@en
P2093
P304
P31
P407
P433
P478
P577
P698