Altered airway and cardiac responses in mice lacking G protein-coupled receptor kinase 3
about
Leukocyte analysis from WHIM syndrome patients reveals a pivotal role for GRK3 in CXCR4 signalingCrosstalk between beta-2-adrenoceptor and muscarinic acetylcholine receptors in the airwayG protein coupled receptor kinases as therapeutic targets in cardiovascular disease.Beta-arrestin-2 regulates the development of allergic asthmaTissue inflammation and nitric oxide-mediated alterations in cardiovascular function are major determinants of endotoxin-induced insulin resistanceChronic treatment in vivo with β-adrenoceptor agonists induces dysfunction of airway β(2) -adrenoceptors and exacerbates lung inflammation in mice.Beta-arrestins specifically constrain beta2-adrenergic receptor signaling and function in airway smooth muscleRegulation of M2-type pyruvate kinase mediated by the high-affinity IgE receptors is required for mast cell degranulation.Multistrain genetic comparisons reveal CCR5 as a receptor involved in airway hyperresponsiveness.A robust protocol for regional evaluation of methacholine challenge in mouse models of allergic asthma using hyperpolarized 3He MRI.Lentivirus vector-mediated Rho guanine nucleotide dissociation inhibitor 2 overexpression induces beta-2 adrenergic receptor desensitization in airway smooth muscle cells.G protein-coupled receptor kinase-3-deficient mice exhibit WHIM syndrome features and attenuated inflammatory responses.Targeted transgenesis reveals discrete attenuator functions of GRK and PKA in airway beta2-adrenergic receptor physiologic signalingNoncanonical Roles of G Protein-coupled Receptor Kinases in Cardiovascular Signaling.G protein-coupled receptor kinase 5 contains a DNA-binding nuclear localization sequence.G Protein-Coupled Receptor Kinases in the Inflammatory Response and Signaling.
P2860
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P2860
Altered airway and cardiac responses in mice lacking G protein-coupled receptor kinase 3
description
1999 nî lūn-bûn
@nan
1999 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
1999年の論文
@ja
1999年論文
@yue
1999年論文
@zh-hant
1999年論文
@zh-hk
1999年論文
@zh-mo
1999年論文
@zh-tw
1999年论文
@wuu
name
Altered airway and cardiac responses in mice lacking G protein-coupled receptor kinase 3
@ast
Altered airway and cardiac responses in mice lacking G protein-coupled receptor kinase 3
@en
Altered airway and cardiac responses in mice lacking G protein-coupled receptor kinase 3
@nl
type
label
Altered airway and cardiac responses in mice lacking G protein-coupled receptor kinase 3
@ast
Altered airway and cardiac responses in mice lacking G protein-coupled receptor kinase 3
@en
Altered airway and cardiac responses in mice lacking G protein-coupled receptor kinase 3
@nl
prefLabel
Altered airway and cardiac responses in mice lacking G protein-coupled receptor kinase 3
@ast
Altered airway and cardiac responses in mice lacking G protein-coupled receptor kinase 3
@en
Altered airway and cardiac responses in mice lacking G protein-coupled receptor kinase 3
@nl
P2093
P1476
Altered airway and cardiac responses in mice lacking G protein-coupled receptor kinase 3
@en
P2093
J K Walker
R J Lefkowitz
P304
P356
10.1152/AJPREGU.1999.276.4.R1214
P407
P577
1999-04-01T00:00:00Z