New role for epoxyeicosatrienoic acids as anti-inflammatory mediators
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Fragment Screening of Soluble Epoxide Hydrolase for Lead Generation-Structure-Based Hit Evaluation and Chemistry ExplorationSoluble epoxide hydrolase inhibitors and heart failureRed blood cells (RBCs), epoxyeicosatrienoic acids (EETs) and adenosine triphosphate (ATP)Pharmacokinetic optimization of four soluble epoxide hydrolase inhibitors for use in a murine model of inflammationSoluble epoxide hydrolase gene deletion attenuates renal injury and inflammation with DOCA-salt hypertensionVariation in the human soluble epoxide hydrolase gene and risk of restenosis after percutaneous coronary interventionBioactive lipid profiling reveals drug target engagement of a soluble epoxide hydrolase inhibitor in a murine model of tobacco smoke exposureAltered behavioral phenotypes in soluble epoxide hydrolase knockout mice: effects of traumatic brain injuryInhibition of soluble epoxide hydrolase enhances the anti-inflammatory effects of aspirin and 5-lipoxygenase activation protein inhibitor in a murine modelBeneficial effects of soluble epoxide hydrolase inhibitors in myocardial infarction model: Insight gained using metabolomic approachesAttenuation of tobacco smoke-induced lung inflammation by treatment with a soluble epoxide hydrolase inhibitorAnalysis of epoxyeicosatrienoic acids by chiral liquid chromatography/electron capture atmospheric pressure chemical ionization mass spectrometry using [13C]-analog internal standards.Mice deficient in intestinal epithelium cytochrome P450 reductase are prone to acute toxin-induced mucosal damage.The role of epoxide hydrolases in health and disease.Epoxide hydrolase and epoxygenase metabolites as therapeutic targets for renal diseases.CYP2J2 targeting to endothelial cells attenuates adiposity and vascular dysfunction in mice fed a high-fat diet by reprogramming adipocyte phenotype.Metabolic signatures of extreme longevity in northern Italian centenarians reveal a complex remodeling of lipids, amino acids, and gut microbiota metabolism.Temporal changes of cytochrome P450 (Cyp) and eicosanoid-related gene expression in the rat brain after traumatic brain injury.Inhibition of NF-kappaB activation by 5-lipoxygenase inhibitors protects brain against injury in a rat model of focal cerebral ischemia.Inhibition of soluble epoxide hydrolase reduces food intake and increases metabolic rate in obese mice.Prevention and reversal of cardiac hypertrophy by soluble epoxide hydrolase inhibitors.Synthesis and structure-activity relationship studies of urea-containing pyrazoles as dual inhibitors of cyclooxygenase-2 and soluble epoxide hydrolaseOphiopogonin D maintains Ca2+ homeostasis in rat cardiomyocytes in vitro by upregulating CYP2J3/EETs and suppressing ER stress.Eicosanoids and renal damage in cardiometabolic syndrome.Soluble epoxide hydrolase null mice exhibit female and male differences in regulation of vascular homeostasisStimulation of rat erythrocyte P2X7 receptor induces the release of epoxyeicosatrienoic acids.Characterization of the non-adrenergic/non-cholinergic response to perivascular nerve stimulation in the double-perfused mesenteric bed of the mouseStructure-activity relationships of cycloalkylamide derivatives as inhibitors of the soluble epoxide hydrolase.Chemokine receptor 2b inhibition provides renal protection in angiotensin II - salt hypertension.Administration of a substituted adamantyl urea inhibitor of soluble epoxide hydrolase protects the kidney from damage in hypertensive Goto-Kakizaki rats.Antiinflammatory and neuroprotective actions of COX2 inhibitors in the injured brain.Epoxyeicosatrienoic Acids Regulate Adipocyte Differentiation of Mouse 3T3 Cells, Via PGC-1α Activation, Which Is Required for HO-1 Expression and Increased Mitochondrial FunctionSorafenib has soluble epoxide hydrolase inhibitory activity, which contributes to its effect profile in vivo.Significance of brain tissue oxygenation and the arachidonic acid cascade in stroke.Understanding resolvin signaling pathways to improve oral healthInfluence of inflammation on cardiovascular protective effects of cytochrome P450 epoxygenase-derived epoxyeicosatrienoic acids.Targeted chiral analysis of bioactive arachidonic Acid metabolites using liquid-chromatography-mass spectrometry.Cytochrome P450 eicosanoids in cerebrovascular function and disease.Participation of epoxygenase activation in saikogenin D-induced inhibition of prostaglandin E(2) synthesis.Molecular determinants of cardiac K(ATP) channel activation by epoxyeicosatrienoic acids.
P2860
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P2860
New role for epoxyeicosatrienoic acids as anti-inflammatory mediators
description
2000 nî lūn-bûn
@nan
2000 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
New role for epoxyeicosatrienoic acids as anti-inflammatory mediators
@ast
New role for epoxyeicosatrienoic acids as anti-inflammatory mediators
@en
New role for epoxyeicosatrienoic acids as anti-inflammatory mediators
@nl
type
label
New role for epoxyeicosatrienoic acids as anti-inflammatory mediators
@ast
New role for epoxyeicosatrienoic acids as anti-inflammatory mediators
@en
New role for epoxyeicosatrienoic acids as anti-inflammatory mediators
@nl
prefLabel
New role for epoxyeicosatrienoic acids as anti-inflammatory mediators
@ast
New role for epoxyeicosatrienoic acids as anti-inflammatory mediators
@en
New role for epoxyeicosatrienoic acids as anti-inflammatory mediators
@nl
P1476
New role for epoxyeicosatrienoic acids as anti-inflammatory mediators
@en
P2093
W B Campbell
P356
10.1016/S0165-6147(00)01472-3
P407
P577
2000-04-01T00:00:00Z