3'-azido-3'-deoxythimidine (AZT) is glucuronidated by human UDP-glucuronosyltransferase 2B7 (UGT2B7)
about
Molecular cloning of the baboon UDP-glucuronosyltransferase 2B gene family and their activity in conjugating morphineInterindividual variability in pharmacokinetics of generic nucleoside reverse transcriptase inhibitors in TB/HIV-coinfected Ghanaian patients: UGT2B7*1c is associated with faster zidovudine clearance and glucuronidationStructure and Protein-Protein Interactions of Human UDP-GlucuronosyltransferasesImproved Safety, Bioavailability and Pharmacokinetics of Zidovudine through Lactoferrin Nanoparticles during Oral Administration in RatsA genome-wide association study identifies UGT1A1 as a regulator of serum cell-free DNA in young adults: The Cardiovascular Risk in Young Finns Study.Diabetes mellitus reduces activity of human UDP-glucuronosyltransferase 2B7 in liver and kidney leading to decreased formation of mycophenolic acid acyl-glucuronide metabolite.Contribution of N-glucuronidation to efavirenz elimination in vivo in the basal and rifampin-induced metabolism of efavirenz.Impact of UGT2B7 His268Tyr polymorphism on the outcome of adjuvant epirubicin treatment in breast cancer.In vitro evidence for endocrine-disrupting chemical (EDC)'s inhibition of drug metabolism.S-Naproxen and desmethylnaproxen glucuronidation by human liver microsomes and recombinant human UDP-glucuronosyltransferases (UGT): role of UGT2B7 in the elimination of naproxen.Worldwide variation in human drug-metabolism enzyme genes CYP2B6 and UGT2B7: implications for HIV/AIDS treatment.From pediatric covariate model to semiphysiological function for maturation: part I-extrapolation of a covariate model from morphine to Zidovudine.From Pediatric Covariate Model to Semiphysiological Function for Maturation: Part II-Sensitivity to Physiological and Physicochemical PropertiesPrevalence of UGT1A9 and UGT2B7 nonsynonymous single nucleotide polymorphisms in West African, Papua New Guinean, and North American populations.In vitro glucuronidation of fenofibric acid by human UDP-glucuronosyltransferases and liver microsomes.Prevalence of UDP-glucuronosyltransferase polymorphisms (UGT1A6∗2, 1A7∗12, 1A8∗3, 1A9∗3, 2B7∗2, and 2B15∗2) in a Saudi population.The sonic hedgehog factor GLI1 imparts drug resistance through inducible glucuronidation.Oral drug absorption in pediatrics: the intestinal wall, its developmental changes and current tools for predictions.Differential gene expression in human hepatocyte cell lines exposed to the antiretroviral agent zidovudine.Acute liver failure enhances oral plasma exposure of zidovudine in rats by downregulation of hepatic UGT2B7 and intestinal P-gp.In vitro glucuronidation of aprepitant: a moderate inhibitor of UGT2B7.Glucuronidation of the antiretroviral drug efavirenz by UGT2B7 and an in vitro investigation of drug-drug interaction with zidovudine.Mechanisms and the clinical relevance of complex drug-drug interactions
P2860
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P2860
3'-azido-3'-deoxythimidine (AZT) is glucuronidated by human UDP-glucuronosyltransferase 2B7 (UGT2B7)
description
2000 nî lūn-bûn
@nan
2000 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
3'-azido-3'-deoxythimidine (AZ ...... onosyltransferase 2B7 (UGT2B7)
@ast
3'-azido-3'-deoxythimidine (AZ ...... onosyltransferase 2B7 (UGT2B7)
@en
3'-azido-3'-deoxythimidine (AZ ...... onosyltransferase 2B7 (UGT2B7)
@nl
type
label
3'-azido-3'-deoxythimidine (AZ ...... onosyltransferase 2B7 (UGT2B7)
@ast
3'-azido-3'-deoxythimidine (AZ ...... onosyltransferase 2B7 (UGT2B7)
@en
3'-azido-3'-deoxythimidine (AZ ...... onosyltransferase 2B7 (UGT2B7)
@nl
prefLabel
3'-azido-3'-deoxythimidine (AZ ...... onosyltransferase 2B7 (UGT2B7)
@ast
3'-azido-3'-deoxythimidine (AZ ...... onosyltransferase 2B7 (UGT2B7)
@en
3'-azido-3'-deoxythimidine (AZ ...... onosyltransferase 2B7 (UGT2B7)
@nl
P2093
P3181
P1476
3'-azido-3'-deoxythimidine (AZ ...... onosyltransferase 2B7 (UGT2B7)
@en
P2093
A Bélanger
T R Tephly
P304
P3181
P407
P577
2000-05-01T00:00:00Z