Rescue of hearing, auditory hair cells, and neurons by CEP-1347/KT7515, an inhibitor of c-Jun N-terminal kinase activation
about
Strategies for developing novel therapeutics for sensorineural hearing loss.Noise exposure immediately activates cochlear mitogen-activated protein kinase signalingThe MLK family mediates c-Jun N-terminal kinase activation in neuronal apoptosisNew developments in aminoglycoside therapy and ototoxicityAge-related hearing impairment and the triad of acquired hearing loss.The cochlea as an independent neuroendocrine organ: expression and possible roles of a local hypothalamic-pituitary-adrenal axis-equivalent signaling systemJNK Inhibition Inhibits Lateral Line Neuromast Hair Cell Development.Mechanisms of aminoglycoside ototoxicity and targets of hair cell protection.Role of somatostatin receptor-2 in gentamicin-induced auditory hair cell loss in the Mammalian inner earBag1-L is a phosphorylation-dependent coactivator of c-Jun during neuronal apoptosis.Antioxidants reduce cellular and functional changes induced by intense noise in the inner ear and cochlear nucleus.Intracochlear drug delivery in combination with cochlear implants : Current aspectsImmune defense is the primary function associated with the differentially expressed genes in the cochlea following acoustic traumaExtracellular divalent cations modulate aminoglycoside-induced hair cell death in the zebrafish lateral linec-Jun N-Terminal Phosphorylation: Biomarker for Cellular Stress Rather than Cell Death in the Injured Cochlea.Validation of Reference Genes for RT-qPCR Analysis in Noise-Induced Hearing Loss: A Study in Wistar RatMechanisms of sensorineural cell damage, death and survival in the cochlea.Molecular regulation of auditory hair cell death and approaches to protect sensory receptor cells and/or stimulate repair following acoustic trauma.A novel role of cytosolic protein synthesis inhibition in aminoglycoside ototoxicity.Supporting cells eliminate dying sensory hair cells to maintain epithelial integrity in the avian inner ear.Cisplatin and aminoglycoside antibiotics: hearing loss and its prevention.Efficacy of three drugs for protecting against gentamicin-induced hair cell and hearing losses.Intracellular mechanisms of aminoglycoside-induced cytotoxicity.The miR-183/Taok1 target pair is implicated in cochlear responses to acoustic trauma.The cochlear CRF signaling systems and their mechanisms of action in modulating cochlear sensitivity and protection against trauma.Protection from impulse noise-induced hearing loss with novel Src-protein tyrosine kinase inhibitors.Apoptosis in acquired and genetic hearing impairment: the programmed death of the hair cellThe design and screening of drugs to prevent acquired sensorineural hearing lossNoise-induced changes in gene expression in the cochleae of mice differing in their susceptibility to noise damageAblation of mixed lineage kinase 3 (Mlk3) does not inhibit ototoxicity induced by acoustic trauma or aminoglycoside exposure.Therapy of hearing disorders - conservative procedures.Current aspects of hearing loss from occupational and leisure noiseThe caspase pathway in noise-induced apoptosis of the chinchilla cochlea.Neomycin-induced hair cell death and rapid regeneration in the lateral line of zebrafish (Danio rerio).Celastrol inhibits aminoglycoside-induced ototoxicity via heat shock protein 32.Transcriptomic analysis of the zebrafish inner ear points to growth hormone mediated regeneration following acoustic traumaResponse of mechanosensory hair cells of the zebrafish lateral line to aminoglycosides reveals distinct cell death pathways.Future approaches for inner ear protection and repair.A corticotropin-releasing factor system expressed in the cochlea modulates hearing sensitivity and protects against noise-induced hearing lossPivotal role of Harakiri in the induction and prevention of gentamicin-induced hearing loss.
P2860
Q21129270-C5F49136-8E3E-445B-8E99-020402AB793BQ23916444-F9759C2A-ADC3-49B3-8C59-CC2ED907BB64Q24550921-95249455-D5DB-4B91-A883-FD9923E7328CQ24599985-2978ABE1-370E-45AF-963F-75E997AC99FCQ26797403-DAC57FCE-BF82-444A-A024-81276BF032FCQ26996598-D7F63A8A-8527-421E-A305-52C151E6FC51Q27320018-44C8B1FA-A1E1-41A0-92E9-F1268F9FE399Q28393038-1CC2ABF0-688E-4326-A2D0-04525AD2EDB7Q28543409-7C16BA4A-9C84-4CA8-A370-3F5ED2B8C3DEQ28589005-4BAD0FFC-4C47-45AE-9C5E-7F9491E6660AQ28917051-E1B95F05-5BBC-4083-B913-3B7B839DE460Q30313632-3EE2830E-E6D3-472B-BFE3-B246D1EF2ADCQ30362202-7850E869-3B11-4EAD-9EC7-349649C617F3Q30368370-FAA1A2CD-5617-4BE8-816C-20DAC92AFEADQ30382124-459A0DAF-38B5-42B7-9697-20F4FCF50F8BQ30402745-B550CF29-84A1-4606-A0EB-95B1D5B816C4Q30412447-E626C4E6-5C6C-4B4F-92E5-98433D48EE80Q30414386-0A69F694-AF62-4D66-BD37-58ED15AEDC3EQ30417680-BB2E31E5-C49E-410D-B5A6-ABF3514CAF4AQ30433076-FBBC5DED-DC51-423A-9820-195610A1C1E0Q30447637-E82B9BBB-A50F-41FC-8C9E-A65C034247CCQ30452815-E8BFB8CD-1801-41DE-9937-7F3DF2243719Q30454411-3356E541-A247-4226-AEAF-F89276A1C2A9Q30457564-90818BB4-30A5-4E09-9455-E3C1B86F63AAQ30460358-2DDDE1D4-A10B-43CD-B781-6F0C5F5F38D5Q30460365-CF391371-854E-4633-B696-E3A6504E78E6Q30461482-3BAEC16E-BAEA-43AB-A4AC-46B3D9C3D6A9Q30465748-B44B7E3F-E977-4BD6-9582-333B2BCAE520Q30466128-3D04AA88-A34C-45E7-918B-1EA69154F506Q30472512-C662200F-AEFD-49F2-B497-D6E8C8010AEFQ30473039-1E9EFFA7-79BF-481A-833D-1ED7AAA4ED7FQ30473044-685790F4-E11A-4E2E-A4C5-D0F3C895CD34Q30473436-12763377-8DAE-4EFE-AD8A-F56F2B459189Q30473445-C31505E9-0195-454E-BB81-A30E31F82DF8Q30473659-F8F24521-C388-43FA-B535-0461B17778A2Q30474115-B3ECC4AD-FF1A-4F24-B7BC-0F03F76903F0Q30474223-153447CD-591A-4279-9F88-0990225F6767Q30474951-1C319D7A-FB34-4CFF-B5DE-C0DF51877B96Q30475696-68542B9D-101F-4D59-BDE9-A555698B25ABQ30476336-613CDC48-DDB2-4479-9A6C-79065D76B85E
P2860
Rescue of hearing, auditory hair cells, and neurons by CEP-1347/KT7515, an inhibitor of c-Jun N-terminal kinase activation
description
2000 nî lūn-bûn
@nan
2000 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2000年の論文
@ja
2000年論文
@yue
2000年論文
@zh-hant
2000年論文
@zh-hk
2000年論文
@zh-mo
2000年論文
@zh-tw
2000年论文
@wuu
name
Rescue of hearing, auditory ha ...... n N-terminal kinase activation
@ast
Rescue of hearing, auditory ha ...... n N-terminal kinase activation
@en
Rescue of hearing, auditory ha ...... n N-terminal kinase activation
@nl
type
label
Rescue of hearing, auditory ha ...... n N-terminal kinase activation
@ast
Rescue of hearing, auditory ha ...... n N-terminal kinase activation
@en
Rescue of hearing, auditory ha ...... n N-terminal kinase activation
@nl
prefLabel
Rescue of hearing, auditory ha ...... n N-terminal kinase activation
@ast
Rescue of hearing, auditory ha ...... n N-terminal kinase activation
@en
Rescue of hearing, auditory ha ...... n N-terminal kinase activation
@nl
P2093
P1476
Rescue of hearing, auditory ha ...... n N-terminal kinase activation
@en
P2093
A M Camoratto
C Murakata
J Virkkala
J Ylikoski
K M Walton
L Xing-Qun
P356
10.1523/JNEUROSCI.20-01-00043.2000
P407
P577
2000-01-01T00:00:00Z