A small molecule CXCR4 inhibitor that blocks T cell line-tropic HIV-1 infection - Wikidata - awgldk - TriplyDB

A small molecule CXCR4 inhibitor that blocks T cell line-tropic HIV-1 infection

A small molecule CXCR4 inhibitor that blocks T cell line-tropic HIV-1 infection

http://www.wikidata.org/entity/Q28379184

about

Viral entry through CXCR4 is a pathogenic factor and therapeutic target in human immunodeficiency virus type 1 disease CCR5, GPR15, and CXCR6 are major coreceptors of human immunodeficiency virus type 2 variants isolated from individuals with and without plasma viremia Studies on anticancer activities of antimicrobial peptides Selective CXCR4 antagonism by Tat: implications for in vivo expansion of coreceptor use by HIV-1 HIV type I envelope determinants for use of the CCR2b, CCR3, STRL33, and APJ coreceptors HIV entry inhibitors: mechanisms of action and resistance pathways Inhibitory mechanism of the CXCR4 antagonist T22 against human immunodeficiency virus type 1 infection.The CXCR4 antagonist AMD3100 efficiently inhibits cell-surface-expressed human immunodeficiency virus type 1 envelope-induced apoptosis A binding pocket for a small molecule inhibitor of HIV-1 entry within the transmembrane helices of CCR5 Role of human immunodeficiency virus (HIV) type 1 envelope in the anti-HIV activity of the betulinic acid derivative IC9564 T134, a small-molecule CXCR4 inhibitor, has no cross-drug resistance with AMD3100, a CXCR4 antagonist with a different structure.The anti-HIV pseudopeptide HB-19 forms a complex with the cell-surface-expressed nucleolin independent of heparan sulfate proteoglycans Inhibition of the human chemokine receptor CXCR4 by antisense phosphorothioate oligodeoxyribonucleotides.Small neutralizing molecules to inhibit actions of the chemokine CXCL12.Comparison of cell-based assays for the identification and evaluation of competitive CXCR4 inhibitors.HIV coreceptors, cell tropism and inhibition by chemokine receptor ligands.HIV-1 envelope determinants for cell tropism and chemokine receptor use.Animal antimicrobial peptides: an overview.Human immunodeficiency virus type 1 entry and chemokine receptors: a new therapeutic target.Identification of CXCR4 domains that support coreceptor and chemokine receptor functions The role of chemokine receptors in HIV infection.Preferential use of CXCR4 by R5X4 human immunodeficiency virus type 1 isolates for infection of primary lymphocytes Interference with the signaling capacity of CC chemokine receptor 5 can compromise its role as an HIV-1 entry coreceptor in primary T lymphocytes.HIV Nef-M1 Effects on Colorectal Cancer Growth in Tumor-induced Spleens and Hepatic Metastasis Genetic evidence for an interaction between human immunodeficiency virus type 1 matrix and alpha-helix 2 of the gp41 cytoplasmic tail.Identification of a key target sequence to block human immunodeficiency virus type 1 replication within the gag-pol transframe domain.Simian immunodeficiency viruses of diverse origin can use CXCR4 as a coreceptor for entry into human cells A cell line-based neutralization assay for primary human immunodeficiency virus type 1 isolates that use either the CCR5 or the CXCR4 coreceptor.Antigenically distinct conformations of CXCR4.Novel compounds in preclinical/early clinical development for the treatment of HIV infections.Current lead natural products for the chemotherapy of human immunodeficiency virus (HIV) infection.Retrocyclin: a primate peptide that protects cells from infection by T- and M-tropic strains of HIV-1.env chimeric virus technology for evaluating human immunodeficiency virus susceptibility to entry inhibitors.Nef-M1, a CXCR4 Peptide Antagonist, Enhances Apoptosis and Inhibits Primary Tumor Growth and Metastasis in Breast Cancer The role of chemoattraction in cancer metastases.A designed peptide targeting CXCR4 displays anti-acute myelocytic leukemia activity in vitro and in vivo.Low-molecular-weight CXCR4 ligands with variable spacers.Peptides trap the human immunodeficiency virus type 1 envelope glycoprotein fusion intermediate at two sites Fragment-based optimization of small molecule CXCL12 inhibitors for antagonizing the CXCL12/CXCR4 interaction.Cell-free assay of G-protein-coupled receptors using fluorescence polarization.

P2860

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P2860

A small molecule CXCR4 inhibitor that blocks T cell line-tropic HIV-1 infection

http://www.wikidata.org/entity/Q28379184

description

1997 nî lūn-bûn

@nan

1997 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած

@hyw

1997 թվականի հոտեմբերին հրատարակված գիտական հոդված

@hy

1997年の論文

@ja

1997年論文

@yue

1997年論文

@zh-hant

1997年論文

@zh-hk

1997年論文

@zh-mo

1997年論文

@zh-tw

1997年论文

@wuu

name

A small molecule CXCR4 inhibitor that blocks T cell line-tropic HIV-1 infection

@ast

A small molecule CXCR4 inhibitor that blocks T cell line-tropic HIV-1 infection

@en

A small molecule CXCR4 inhibitor that blocks T cell line-tropic HIV-1 infection

@nl

type

label

A small molecule CXCR4 inhibitor that blocks T cell line-tropic HIV-1 infection

@ast

A small molecule CXCR4 inhibitor that blocks T cell line-tropic HIV-1 infection

@en

A small molecule CXCR4 inhibitor that blocks T cell line-tropic HIV-1 infection

@nl

prefLabel

A small molecule CXCR4 inhibitor that blocks T cell line-tropic HIV-1 infection

@ast

A small molecule CXCR4 inhibitor that blocks T cell line-tropic HIV-1 infection

@en

A small molecule CXCR4 inhibitor that blocks T cell line-tropic HIV-1 infection

@nl

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P1433

Journal of Experimental Medicine

P1476

A small molecule CXCR4 inhibitor that blocks T cell line-tropic HIV-1 infection

@en

P2093

A Matsumoto

http://www.w3.org/2001/XMLSchema#string

H Tamamura

http://www.w3.org/2001/XMLSchema#string

K Tachibana

http://www.w3.org/2001/XMLSchema#string

M Waki

http://www.w3.org/2001/XMLSchema#string

N Fujii

http://www.w3.org/2001/XMLSchema#string

N Yamamoto

http://www.w3.org/2001/XMLSchema#string

N Yoshida

http://www.w3.org/2001/XMLSchema#string

O Yoshie

http://www.w3.org/2001/XMLSchema#string

T Kishimoto

http://www.w3.org/2001/XMLSchema#string

T Murakami

http://www.w3.org/2001/XMLSchema#string

P2860

HIV-1 Entry Cofactor: Functional cDNA Cloning of a Seven-Transmembrane, G Protein-Coupled Receptor

Identification of a major co-receptor for primary isolates of HIV-1

The lymphocyte chemoattractant SDF-1 is a ligand for LESTR/fusin and blocks HIV-1 entry

A dual-tropic primary HIV-1 isolate that uses fusin and the beta-chemokine receptors CKR-5, CKR-3, and CKR-2b as fusion cofactors

Identification of RANTES, MIP-1 alpha, and MIP-1 beta as the major HIV-suppressive factors produced by CD8+ T cells

The beta-chemokine receptors CCR3 and CCR5 facilitate infection by primary HIV-1 isolates

Anti-human immunodeficiency virus activity of a novel synthetic peptide, T22 ([Tyr-5,12, Lys-7]polyphemusin II): a possible inhibitor of virus-cell fusion

Molecular cloning and characterization of a murine pre-B-cell growth-stimulating factor/stromal cell-derived factor 1 receptor, a murine homolog of the human immunodeficiency virus 1 entry coreceptor fusin

CC CKR5: a RANTES, MIP-1alpha, MIP-1beta receptor as a fusion cofactor for macrophage-tropic HIV-1

Production of acquired immunodeficiency syndrome-associated retrovirus in human and nonhuman cells transfected with an infectious molecular clone

P304

1389-93

http://www.w3.org/2001/XMLSchema#string

P31

scholarly article

P356

10.1084/JEM.186.8.1389

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P407

P433

8

http://www.w3.org/2001/XMLSchema#string

P478

186

http://www.w3.org/2001/XMLSchema#string

P577

1997-10-20T00:00:00Z

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P5875

13893759

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P698

9334379

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P932

2199089

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