Hemin causes mitochondrial dysfunction in endothelial cells through promoting lipid peroxidation: the protective role of autophagy - Wikidata - awgldk - TriplyDB

Hemin causes mitochondrial dysfunction in endothelial cells through promoting lipid peroxidation: the protective role of autophagy

Hemin causes mitochondrial dysfunction in endothelial cells through promoting lipid peroxidation: the protective role of autophagy

http://www.wikidata.org/entity/Q28383654

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The Role of Autophagy, Mitophagy and Lysosomal Functions in Modulating Bioenergetics and Survival in the Context of Redox and Proteotoxic Damage: Implications for Neurodegenerative Diseases Oxidative stress-induced autophagy: role in pulmonary toxicity Cytosolic peroxidases protect the lysosome of bloodstream African trypanosomes from iron-mediated membrane damage The electrophile responsive proteome: integrating proteomics and lipidomics with cellular function Teaching the basics of autophagy and mitophagy to redox biologists--mechanisms and experimental approaches Mitophagy mechanisms and role in human diseases Redox biology and the interface between bioenergetics, autophagy and circadian control of metabolism Bioenergetic adaptation in response to autophagy regulators during rotenone exposure Mitochondria, endothelial cell function, and vascular diseases.PDGF-mediated autophagy regulates vascular smooth muscle cell phenotype and resistance to oxidative stress Redox regulation of antioxidants, autophagy, and the response to stress: implications for electrophile therapeutics.Role of heme in cardiovascular physiology and disease.Proteasome inhibition and oxidative reactions disrupt cellular homeostasis during heme stress Autophagy: an emerging therapeutic target in vascular diseases Fructose Mediated Non-Alcoholic Fatty Liver Is Attenuated by HO-1-SIRT1 Module in Murine Hepatocytes and Mice Fed a High Fructose Diet.Decreased Bioenergetic Health Index in monocytes isolated from the pericardial fluid and blood of post-operative cardiac surgery patients.Mutations in the Heme Exporter FLVCR1 Cause Sensory Neurodegeneration with Loss of Pain Perception Sickle Cell Hemoglobin in the Ferryl State Promotes βCys-93 Oxidation and Mitochondrial Dysfunction in Epithelial Lung Cells (E10)Shear stress regulates endothelial cell autophagy via redox regulation and Sirt1 expression.Neuroprotective role of prostaglandin PGE2 EP2 receptor in hemin-mediated toxicity.Integration of cellular bioenergetics with mitochondrial quality control and autophagy.Apolipoprotein E-/- Mice Lacking Hemopexin Develop Increased Atherosclerosis via Mechanisms That Include Oxidative Stress and Altered Macrophage Function.Mitochondria and endothelial function Restoration of autophagy in endothelial cells from patients with diabetes mellitus improves nitric oxide signaling.Mitochondria-targeted heme oxygenase-1 decreases oxidative stress in renal epithelial cells Oxidized lipids activate autophagy in a JNK-dependent manner by stimulating the endoplasmic reticulum stress response Detection of electrophile-sensitive proteins.Assessing Cardiac Metabolism: A Scientific Statement From the American Heart Association.Plasma heme-induced renal toxicity is related to a capillary rarefaction.Therapeutic targeting of oxygen-sensing prolyl hydroxylases abrogates ATF4-dependent neuronal death and improves outcomes after brain hemorrhage in several rodent models.Cellular metabolic and autophagic pathways: traffic control by redox signaling.Mitochondria: a pathogenic paradigm in hypertensive renal disease.Oxidized Ferric and Ferryl Forms of Hemoglobin Trigger Mitochondrial Dysfunction and Injury in Alveolar Type I Cells.Upregulation of autophagy decreases chlorine-induced mitochondrial injury and lung inflammation.Mitochondria in endothelial cells: Sensors and integrators of environmental cues.The Bioenergetic Health Index is a sensitive measure of oxidative stress in human monocytes.Mitochondrially targeted compounds and their impact on cellular bioenergetics.Inhibition of autophagy and glycolysis by nitric oxide during hypoxia-reoxygenation impairs cellular bioenergetics and promotes cell death in primary neurons Mitochondria-targeted heme oxygenase-1 induces oxidative stress and mitochondrial dysfunction in macrophages, kidney fibroblasts and in chronic alcohol hepatotoxicity Utilization of fluorescent probes for the quantification and identification of subcellular proteomes and biological processes regulated by lipid peroxidation products.

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P2860

Hemin causes mitochondrial dysfunction in endothelial cells through promoting lipid peroxidation: the protective role of autophagy

http://www.wikidata.org/entity/Q28383654

description

2012 nî lūn-bûn

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2012 թուականի Ապրիլին հրատարակուած գիտական յօդուած

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2012 թվականի ապրիլին հրատարակված գիտական հոդված

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2012年の論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年論文

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2012年论文

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name

Hemin causes mitochondrial dys ...... e protective role of autophagy

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Hemin causes mitochondrial dys ...... e protective role of autophagy

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Hemin causes mitochondrial dys ...... e protective role of autophagy

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type

label

Hemin causes mitochondrial dys ...... e protective role of autophagy

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Hemin causes mitochondrial dys ...... e protective role of autophagy

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Hemin causes mitochondrial dys ...... e protective role of autophagy

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prefLabel

Hemin causes mitochondrial dys ...... e protective role of autophagy

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Hemin causes mitochondrial dys ...... e protective role of autophagy

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Hemin causes mitochondrial dys ...... e protective role of autophagy

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American Journal of Physiology - Heart and Circulatory Physiology

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Hemin causes mitochondrial dys ...... e protective role of autophagy

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Ashlee N Higdon

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Balu K Chacko

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Gloria A Benavides

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Jianhua Zhang

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Michelle S Johnson

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Victor M Darley-Usmar

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Xiaosen Ouyang

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P2860

Cytochrome c/cardiolipin relations in mitochondria: a kiss of death

LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing

Mechanisms of mitophagy

Crystal structure of hemopexin reveals a novel high-affinity heme site formed between two beta-propeller domains

Heme binding by hemopexin: evidence for multiple modes of binding and functional implications

Interactions of mitochondria-targeted and untargeted ubiquinones with the mitochondrial respiratory chain and reactive oxygen species. Implications for the use of exogenous ubiquinones as therapies and experimental tools

LC3 conjugation system in mammalian autophagy

Role of hemopexin in protection of low-density lipoprotein against hemoglobin-induced oxidation

Decreased complex II respiration and HNE-modified SDH subunit in diabetic heart

Kinetics of hemin distribution in plasma reveals its role in lipoprotein oxidation

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