Anti-inflammatory Effect of a Cell-Penetrating Peptide Targeting the Nrf2/Keap1 Interaction - Wikidata - awgldk - TriplyDB

Anti-inflammatory Effect of a Cell-Penetrating Peptide Targeting the Nrf2/Keap1 Interaction

Anti-inflammatory Effect of a Cell-Penetrating Peptide Targeting the Nrf2/Keap1 Interaction

http://www.wikidata.org/entity/Q28384313

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Discovery of direct inhibitors of Keap1-Nrf2 protein-protein interaction as potential therapeutic and preventive agents Targeting the Nrf2 Signaling Pathway in the Retina With a Gene-Delivered Secretable and Cell-Penetrating Peptide Repression of the Antioxidant NRF2 Pathway in Premature Aging The status of Nrf2-based therapeutics: current perspectives and future prospects Mycobacterium tuberculosis Induction of Heme Oxygenase-1 Expression Is Dependent on Oxidative Stress and Reflects Treatment Outcomes.Discovery of a small-molecule inhibitor and cellular probe of Keap1-Nrf2 protein-protein interaction Non-electrophilic modulators of the canonical Keap1/Nrf2 pathway Mechanisms underlying the perifocal neuroprotective effect of the Nrf2-ARE signaling pathway after intracranial hemorrhage.Engineering a genetically encoded competitive inhibitor of the KEAP1-NRF2 interaction via structure-based design and phage display.Flavonoid metabolites reduce tumor necrosis factor-α secretion to a greater extent than their precursor compounds in human THP-1 monocytes NAD(P)H:quinone oxidoreductase 1 inducer activity of some novel anilinoquinazoline derivatives Therapeutic potential of cell-penetrating peptides.Overview of Recent Progress in Protein-Expression Technologies for Small-Molecule Screening.Synthesis, molecular modeling and NAD(P)H:quinone oxidoreductase 1 inducer activity of novel 2-phenylquinazolin-4-amine derivatives.The Keap1-Nrf2-ARE Pathway As a Potential Preventive and Therapeutic Target: An Update.Antiapoptotic effect of a novel synthetic peptide from bovine muscle and MPG peptide on H2O2-induced C2C12 cells.A systematic molecular dynamics approach to the study of peptide Keap1-Nrf2 protein-protein interaction inhibitors and its application to p62 peptides.Peptide inhibitors of the Keap1-Nrf2 protein-protein interaction with improved binding and cellular activity.Recent advances in understanding NRF2 as a druggable target: development of pro-electrophilic and non-covalent NRF2 activators to overcome systemic side effects of electrophilic drugs like dimethyl fumarate.Identification of Non-Electrophilic Nrf2 Activators from Approved Drugs.Design and development of Nrf2 modulators for cancer chemoprevention and therapy: a review

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P2860

Anti-inflammatory Effect of a Cell-Penetrating Peptide Targeting the Nrf2/Keap1 Interaction

http://www.wikidata.org/entity/Q28384313

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2012 nî lūn-bûn

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2012 թուականի Մայիսին հրատարակուած գիտական յօդուած

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2012年の論文

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2012年論文

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2012年論文

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2012年論文

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Anti-inflammatory Effect of a ...... ing the Nrf2/Keap1 Interaction

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Anti-inflammatory Effect of a ...... ing the Nrf2/Keap1 Interaction

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Estelle Payerne

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Jonathan Cowan

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Maria A O'Connell

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Mark Searcey

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Richard Steel

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P2860

Multiorgan autoimmune inflammation, enhanced lymphoproliferation, and impaired homeostasis of reactive oxygen species in mice lacking the antioxidant-activated transcription factor Nrf2

Structure of the Keap1:Nrf2 interface provides mechanistic insight into Nrf2 signaling

Isolation of NF-E2-related factor 2 (Nrf2), a NF-E2-like basic leucine zipper transcriptional activator that binds to the tandem NF-E2/AP1 repeat of the beta-globin locus control region

Keap1 represses nuclear activation of antioxidant responsive elements by Nrf2 through binding to the amino-terminal Neh2 domain

Nrf1 and Nrf2 positively and c-Fos and Fra1 negatively regulate the human antioxidant response element-mediated expression of NAD(P)H:quinone oxidoreductase1 gene

An Nrf2/small Maf heterodimer mediates the induction of phase II detoxifying enzyme genes through antioxidant response elements

Nrf2, a Cap'n'Collar transcription factor, regulates induction of the heme oxygenase-1 gene

In vivo protein transduction: delivery of a biologically active protein into the mouse

Peptide inhibitors of the Keap1-Nrf2 protein-protein interaction.

Bardoxolone methyl and kidney function in CKD with type 2 diabetes.

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407-410

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4202024

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10.1021/ML300041G

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5

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22582137

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Aagianik kimischri

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