A novel manganese-dependent ATM-p53 signaling pathway is selectively impaired in patient-based neuroprogenitor and murine striatal models of Huntington's disease
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"Manganese-induced neurotoxicity: a review of its behavioral consequences and neuroprotective strategies"Genomic Instability Associated with p53 Knockdown in the Generation of Huntington's Disease Human Induced Pluripotent Stem CellsMethyl-Arginine Profile of Brain from Aged PINK1-KO+A53T-SNCA Mice Suggests Altered Mitochondrial Biogenesis.iPSC-based drug screening for Huntington's disease.Phosphatidylinositol 3 kinase (PI3K) modulates manganese homeostasis and manganese-induced cell signaling in a murine striatal cell line.Huntington Disease as a Neurodevelopmental Disorder and Early Signs of the Disease in Stem Cells.Induced Pluripotent Stem Cells in Huntington's Disease Research: Progress and Opportunity.Reduced bioavailable manganese causes striatal urea cycle pathology in Huntington's disease mouse model.The Generation of Mouse and Human Huntington Disease iPS Cells Suitable for In vitro Studies on Huntingtin FunctionRecreating blood-brain barrier physiology and structure on chip: A novel neurovascular microfluidic bioreactor.p73 gene in dopaminergic neurons is highly susceptible to manganese neurotoxicity.Huntingtin is a scaffolding protein in the ATM oxidative DNA damage response complex.From the Cover: Manganese and Rotenone-Induced Oxidative Stress Signatures Differ in iPSC-Derived Human Dopamine Neurons.Manganese and the Insulin-IGF Signaling Network in Huntington's Disease and Other Neurodegenerative Disorders.The effect of postnatal manganese exposure on the NMDA receptor signaling pathway in rat hippocampus.
P2860
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P2860
A novel manganese-dependent ATM-p53 signaling pathway is selectively impaired in patient-based neuroprogenitor and murine striatal models of Huntington's disease
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2015 nî lūn-bûn
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2015 թուականի Ապրիլին հրատարակուած գիտական յօդուած
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2015 թվականի ապրիլին հրատարակված գիտական հոդված
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2015年の論文
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2015年論文
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2015年論文
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2015年論文
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2015年論文
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2015年論文
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2015年论文
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name
A novel manganese-dependent AT ...... models of Huntington's disease
@ast
A novel manganese-dependent AT ...... models of Huntington's disease
@en
A novel manganese-dependent AT ...... models of Huntington's disease
@nl
type
label
A novel manganese-dependent AT ...... models of Huntington's disease
@ast
A novel manganese-dependent AT ...... models of Huntington's disease
@en
A novel manganese-dependent AT ...... models of Huntington's disease
@nl
prefLabel
A novel manganese-dependent AT ...... models of Huntington's disease
@ast
A novel manganese-dependent AT ...... models of Huntington's disease
@en
A novel manganese-dependent AT ...... models of Huntington's disease
@nl
P2093
P2860
P50
P921
P3181
P356
P1476
A novel manganese-dependent AT ...... models of Huntington's disease
@en
P2093
Asad A Aboud
Jack E Feist
Kevin C Ess
Kevin K Kumar
M Diana Neely
Michael A Uhouse
Miles R Bryan
P2860
P304
P3181
P356
10.1093/HMG/DDU609
P407
P577
2014-12-08T00:00:00Z