GABAB Receptor Agonist R-Baclofen Reverses Social Deficits and Reduces Repetitive Behavior in Two Mouse Models of Autism - Wikidata - awgldk - TriplyDB

GABAB Receptor Agonist R-Baclofen Reverses Social Deficits and Reduces Repetitive Behavior in Two Mouse Models of Autism

GABAB Receptor Agonist R-Baclofen Reverses Social Deficits and Reduces Repetitive Behavior in Two Mouse Models of Autism

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Behavioral phenotypes of genetic mouse models of autism.Neuronal mechanisms and circuits underlying repetitive behaviors in mouse models of autism spectrum disorder Neurobiology of social behavior abnormalities in autism and Williams syndrome Evaluation of the neuroactive steroid ganaxolone on social and repetitive behaviors in the BTBR mouse model of autism Translational Mouse Models of Autism: Advancing Toward Pharmacological Therapeutics.The Neurobiological Basis for Social Affiliation in Autism Spectrum Disorder and Schizophrenia.Targeting Glia with N-Acetylcysteine Modulates Brain Glutamate and Behaviors Relevant to Neurodevelopmental Disorders in C57BL/6J Mice.Epilepsy and intellectual disability linked protein Shrm4 interaction with GABABRs shapes inhibitory neurotransmission GABA-B Agonist Baclofen Normalizes Auditory-Evoked Neural Oscillations and Behavioral Deficits in the Fmr1 Knockout Mouse Model of Fragile X Syndrome.Autism Spectrum Disorders and Schizophrenia Spectrum Disorders: Excitation/Inhibition Imbalance and Developmental Trajectories.Replicable in vivo physiological and behavioral phenotypes of the Shank3B null mutant mouse model of autism.Using Animal Models to Study the Role of the Gut-Brain Axis in Autism.Young Women do it Better: Sexual Dimorphism in Temporal Discrimination.Hippocampal Transcriptomic and Proteomic Alterations in the BTBR Mouse Model of Autism Spectrum Disorder.Differential surface density and modulatory effects of presynaptic GABAB receptors in hippocampal cholecystokinin and parvalbumin basket cells.Challenges in the development of therapeutics for narcolepsy.Searching for Cross-Diagnostic Convergence: Neural Mechanisms Governing Excitation and Inhibition Balance in Schizophrenia and Autism Spectrum Disorders.Touchscreen learning deficits and normal social approach behavior in the Shank3B model of Phelan-McDermid Syndrome and autism The BTBR mouse model of idiopathic autism - Current view on mechanisms.Neurobiological bases of autism-epilepsy comorbidity: a focus on excitation/inhibition imbalance.Arbaclofen in Children and Adolescents with Autism Spectrum Disorder: A Randomized, Controlled, Phase 2 Trial.Decreased anxiety- and depression-like behaviors and hyperactivity in a type 3 deiodinase-deficient mouse showing brain thyrotoxicosis and peripheral hypothyroidism.Prefrontal cortical GABAergic signaling and impaired behavioral flexibility in aged F344 rats.Autism gene Ube3a and seizures impair sociability by repressing VTA Cbln1.Developmental Disruption of GABAAR-Meditated Inhibition in Cntnap2 KO Mice.Effects of acute administration of the GABA(B) receptor agonist baclofen on behavioral flexibility in rats.Neuronal overexpression of Ube3a isoform 2 causes behavioral impairments and neuroanatomical pathology relevant to 15q11.2-q13.3 duplication syndrome.R-Baclofen Reverses Cognitive Deficits and Improves Social Interactions in Two Lines of 16p11.2 Deletion Mice.Advances in nonhuman primate models of autism: Integrating neuroscience and behavior.Early motor phenotype detection in a female mouse model of Rett syndrome is improved by cross-fostering.Germline Chd8 haploinsufficiency alters brain development in mouse.Altered nocifensive behavior in animal models of autism spectrum disorder: The role of the nicotinic cholinergic system.Animal models for autism in 2017 and the consequential implications to drug discovery.GABBR2 mutations determine phenotype in rett syndrome and epileptic encephalopathy.Behavioral Phenotyping for Autism Spectrum Disorders in Mice.CRF2 receptor-deficiency eliminates social behaviour deficits and vulnerability induced by cocaine.Monosodium glutamate-associated alterations in open field, anxiety-related and conditioned place preference behaviours in mice.Resveratrol Ameliorates Dysregulation of Th1, Th2, Th17, and T Regulatory Cell-Related Transcription Factor Signaling in a BTBR T + tf/J Mouse Model of Autism.Exploring the relationship between cortical GABA concentrations, auditory gamma-band responses and development in ASD: Evidence for an altered maturational trajectory in ASD.Modulation of social deficits and repetitive behaviors in a mouse model of autism: the role of the nicotinic cholinergic system.

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GABAB Receptor Agonist R-Baclofen Reverses Social Deficits and Reduces Repetitive Behavior in Two Mouse Models of Autism

http://www.wikidata.org/entity/Q28391720

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2015 nî lūn-bûn

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2015 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

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2015 թվականի օգոստոսին հրատարակված գիտական հոդված

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2015年の論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年論文

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2015年论文

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GABAB Receptor Agonist R-Baclo ...... in Two Mouse Models of Autism

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Density and function of central serotonin (5-HT) transporters, 5-HT1A and 5-HT2A receptors, and effects of their targeting on BTBR T+tf/J mouse social behavior

Identification of significant association and gene-gene interaction of GABA receptor subunit genes in autism

Marble burying reflects a repetitive and perseverative behavior more than novelty-induced anxiety

GABAB-mediated rescue of altered excitatory-inhibitory balance, gamma synchrony and behavioral deficits following constitutive NMDAR-hypofunction.

Gabrb3 gene deficient mice exhibit impaired social and exploratory behaviors, deficits in non-selective attention and hypoplasia of cerebellar vermal lobules: a potential model of autism spectrum disorder

Common circuit defect of excitatory-inhibitory balance in mouse models of autism.

Behavioral assessment of NIH Swiss mice acutely intoxicated with tetramethylenedisulfotetramine

Negative allosteric modulation of the mGluR5 receptor reduces repetitive behaviors and rescues social deficits in mouse models of autism.

Absence of deficits in social behaviors and ultrasonic vocalizations in later generations of mice lacking neuroligin4.

Bicuculline-insensitive GABA receptors: studies on the binding of (-)-baclofen to rat cerebellar membranes

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