Chronic Deletion and Acute Knockdown of Parkin Have Differential Responses to Acetaminophen-induced Mitophagy and Liver Injury in Mice - Wikidata - awgldk - TriplyDB

Chronic Deletion and Acute Knockdown of Parkin Have Differential Responses to Acetaminophen-induced Mitophagy and Liver Injury in Mice

Chronic Deletion and Acute Knockdown of Parkin Have Differential Responses to Acetaminophen-induced Mitophagy and Liver Injury in Mice

http://www.wikidata.org/entity/Q28392505

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A Mechanistic Review of Mitophagy and Its Role in Protection against Alcoholic Liver Disease Targeting Pink1-Parkin-mediated mitophagy for treating liver injury The Impact of Sterile Inflammation in Acute Liver Injury.Mechanisms of acetaminophen hepatotoxicity and their translation to the human pathophysiology.A cell-based quantitative high-throughput image screening identified novel autophagy modulators Parkin regulates mitophagy and mitochondrial function to protect against alcohol-induced liver injury and steatosis in mice Parkin-mediated mitophagy directs perinatal cardiac metabolic maturation in mice Increased hepatic receptor interacting protein kinase 3 expression due to impaired proteasomal functions contributes to alcohol-induced steatosis and liver injury.Self-renewal of a purified Tie2+ hematopoietic stem cell population relies on mitochondrial clearance.Inhibition of Drp1 protects against senecionine-induced mitochondria-mediated apoptosis in primary hepatocytes and in mice.Parkin-dependent mitophagy in the heart.Genetic compensation: A phenomenon in search of mechanisms.Central Parkin: The evolving role of Parkin in the heart.New methods for monitoring mitochondrial biogenesis and mitophagy in vitro and in vivo.Removal of acetaminophen protein adducts by autophagy protects against acetaminophen-induced liver injury in mice.Tethering Interleukin-22 to Apolipoprotein A-I Ameliorates Mice from Acetaminophen-induced Liver Injury.Dihydroquercetin ameliorated acetaminophen-induced hepatic cytotoxicity via activating JAK2/STAT3 pathway and autophagy.Mechanisms, pathophysiological roles and methods for analyzing mitophagy - recent insights.Does Genetic Loss of Immunoglobulin A Have No Impact on Alcoholic Liver Disease?Melatonin enhances mitophagy and mitochondrial biogenesis in rats with carbon tetrachloride-induced liver fibrosis.Dissecting the molecular pathophysiology of drug-induced liver injury.Resolvin D1 attenuates liver ischaemia/reperfusion injury through modulating thioredoxin 2-mediated mitochondrial quality control.Impaired TFEB-mediated Lysosome Biogenesis and Autophagy Promote Chronic Ethanol-induced Liver Injury and Steatosis in Mice.Mitochondrial-Lysosomal Axis in Acetaminophen Hepatotoxicity.Ethyl pyruvate attenuates acetaminophen-induced liver injury and prevents cellular injury induced by N-acetyl-p-benzoquinone imine.

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Chronic Deletion and Acute Knockdown of Parkin Have Differential Responses to Acetaminophen-induced Mitophagy and Liver Injury in Mice

http://www.wikidata.org/entity/Q28392505

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2015 nî lūn-bûn

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2015 թուականի Ապրիլին հրատարակուած գիտական յօդուած

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2015 թվականի ապրիլին հրատարակված գիտական հոդված

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2015年の論文

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2015年学术文章

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2015年学术文章

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2015年学术文章

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2015年学术文章

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2015年学术文章

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2015年学术文章

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Chronic Deletion and Acute Kno ...... phagy and Liver Injury in Mice

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Chronic Deletion and Acute Kno ...... phagy and Liver Injury in Mice

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Chronic Deletion and Acute Kno ...... phagy and Liver Injury in Mice

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Journal of Biological Chemistry

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Chronic Deletion and Acute Kno ...... phagy and Liver Injury in Mice

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Anna Haynes

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Hartmut Jaeschke

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Hong-Min Ni

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Jessica A Williams

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Wen-Xing Ding

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P2860

PINK1 is selectively stabilized on impaired mitochondria to activate Parkin

Guidelines for the use and interpretation of assays for monitoring autophagy

LC3 binds externalized cardiolipin on injured mitochondria to signal mitophagy in neurons: implications for Parkinson disease

Cardiolipin externalization to the outer mitochondrial membrane acts as an elimination signal for mitophagy in neuronal cells

PINK1/Parkin-mediated mitophagy is dependent on VDAC1 and p62/SQSTM1

Mitochondrial outer-membrane protein FUNDC1 mediates hypoxia-induced mitophagy in mammalian cells

Glycogen synthase kinase-3 regulates mitochondrial outer membrane permeabilization and apoptosis by destabilization of MCL-1

Parkin-dependent degradation of the F-box protein Fbw7β promotes neuronal survival in response to oxidative stress by stabilizing Mcl-1

Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism

Parkin is recruited selectively to impaired mitochondria and promotes their autophagy

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