Analysis of genetic variants in never-smokers with lung cancer facilitated by an Internet-based blood collection protocol: a preliminary report - Wikidata - awgldk - TriplyDB

Analysis of genetic variants in never-smokers with lung cancer facilitated by an Internet-based blood collection protocol: a preliminary report

Analysis of genetic variants in never-smokers with lung cancer facilitated by an Internet-based blood collection protocol: a preliminary report

http://www.wikidata.org/entity/Q28393099

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From men to mice: CHRNA5/CHRNA3, smoking behavior and disease Hereditary lung cancer syndrome targets never smokers with germline EGFR gene T790M mutations Strong association between two polymorphisms on 15q25.1 and lung cancer risk: a meta-analysis Contribution of Variants in CHRNA5/A3/B4 Gene Cluster on Chromosome 15 to Tobacco Smoking: From Genetic Association to Mechanism.Clinical outcome according to the level of preexisting epidermal growth factor receptor T790M mutation in patients with lung cancer harboring sensitive epidermal growth factor receptor mutations.CHRNA3 polymorphism modifies lung adenocarcinoma risk in the Chinese Han population Relationship of p73 gene polymorphism and additional gene-smoking and gene-obesity interaction with non-small cell lung cancer risk Lung cancer trends: smoking, obesity, and sex assessed in the Staten Island University's lung cancer patients.Germ-line mutations in epidermal growth factor receptor (EGFR) are rare but may contribute to oncogenesis: a novel germ-line mutation in EGFR detected in a patient with lung adenocarcinoma.A patient with metastatic lung adenocarcinoma harboring concurrent EGFR L858R, EGFR germline T790M, and PIK3CA mutations: the challenge of interpreting results of comprehensive mutational testing in lung cancer Lung adenocarcinoma from East Asian never-smokers is a disease largely defined by targetable oncogenic mutant kinases.Acquired resistance to EGFR tyrosine kinase inhibitors in EGFR-mutant lung cancer: distinct natural history of patients with tumors harboring the T790M mutation.Rational, biologically based treatment of EGFR-mutant non-small-cell lung cancer.Germline EGFR T790M mutation found in multiple members of a familial cohort.Screening for germline EGFR T790M mutations through lung cancer genotyping.Analyzing large-scale samples confirms the association between the rs1051730 polymorphism and lung cancer susceptibility.Association Between COX-2 Polymorphisms and Lung Cancer Risk Polymorphisms in intron 1 of the EGFR gene in non-small cell lung cancer patients.Family history of lung cancer in never smokers with non-small-cell lung cancer and its association with tumors harboring EGFR mutations.Epidermal growth factor receptor tyrosine kinase inhibitor-resistant disease.Mechanisms of resistance to EGFR targeted therapies.Concurrent molecular alterations in tumors with germ line epidermal growth factor receptor T790M mutations.Germline Mutation of T790M and Dual/Multiple EGFR Mutations in Patients With Lung Adenocarcinoma.Epidermal growth factor receptor mutations in lung adenocarcinoma.Molecular pathways: resistance to kinase inhibitors and implications for therapeutic strategies.Tumor heterogeneity: evolution through space and time in EGFR mutant non small cell lung cancer patients.Known and putative mechanisms of resistance to EGFR targeted therapies in NSCLC patients with EGFR mutations-a review.Germline mutations predisposing to non-small cell lung cancer.Lung Adenocarcinoma with Pulmonary Miliary Metastases and Complex Somatic Heterozygous EGFR Mutation Mechanisms of Resistance to Epidermal Growth Factor Receptor Inhibitors and Novel Therapeutic Strategies to Overcome Resistance in NSCLC Patients.[Effects of EGFR gene polymorphisms on efficacy and prognosis in advanced non-small cell lung cancer treated with EGFR-TKIs].Racial and regional disparities in lung cancer incidence.Non-small cell lung cancer harboring a rare EGFR L747P mutation showing intrinsic resistance to both gefitinib and osimertinib (AZD9291): A case report.Genetic association between AGPHD1 variant and lung cancer risk.Quantitative assessment of the influence of common variations (rs8034191 and rs1051730) at 15q25 and lung cancer risk.Inherited lung cancer syndromes targeting never smokers

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Analysis of genetic variants in never-smokers with lung cancer facilitated by an Internet-based blood collection protocol: a preliminary report

http://www.wikidata.org/entity/Q28393099

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2010 nî lūn-bûn

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2010 թուականի Յունուարին հրատարակուած գիտական յօդուած

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2010 թվականի հունվարին հրատարակված գիտական հոդված

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2010年の論文

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P2860

Lung cancer incidence in never smokers

Radon in homes and risk of lung cancer: collaborative analysis of individual data from 13 European case-control studies

EGF receptor gene mutations are common in lung cancers from "never smokers" and are associated with sensitivity of tumors to gefitinib and erlotinib

PLINK: a tool set for whole-genome association and population-based linkage analyses

Acquired resistance of lung adenocarcinomas to gefitinib or erlotinib is associated with a second mutation in the EGFR kinase domain

Development of new mouse lung tumor models expressing EGFR T790M mutants associated with clinical resistance to kinase inhibitors

Principal components analysis corrects for stratification in genome-wide association studies

Genome-wide association scan of tag SNPs identifies a susceptibility locus for lung cancer at 15q25.1

Activating mutation in the tyrosine kinase JAK2 in polycythemia vera, essential thrombocythemia, and myeloid metaplasia with myelofibrosis

A variant associated with nicotine dependence, lung cancer and peripheral arterial disease

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