F-box protein FBXL2 exerts human lung tumor suppressor-like activity by ubiquitin-mediated degradation of cyclin D3 resulting in cell cycle arrest
about
Kras(G12D) and Nkx2-1 haploinsufficiency induce mucinous adenocarcinoma of the lungF-box protein FBXL2 targets cyclin D2 for ubiquitination and degradation to inhibit leukemic cell proliferationSkp-cullin-F box E3 ligase component FBXL2 ubiquitinates Aurora B to inhibit tumorigenesisTargeting F box protein Fbxo3 to control cytokine-driven inflammationCalmodulin protects Aurora B on the midbody to regulate the fidelity of cytokinesis.Deregulation of F-box proteins and its consequence on cancer development, progression and metastasis.Regulation of TGF-β signaling, exit from the cell cycle, and cellular migration through cullin cross-regulation: SCF-FBXO11 turns off CRL4-Cdt2.Protein homeostasis of a metastable subproteome associated with Alzheimer's disease.F-box protein FBXO31 is down-regulated in gastric cancer and negatively regulated by miR-17 and miR-20a.FBX8 Acts as an Invasion and Metastasis Suppressor and Correlates with Poor Survival in Hepatocellular Carcinoma.Roles of F-box proteins in cancerThe ubiquitin E3 ligase SCF-FBXO24 recognizes deacetylated nucleoside diphosphate kinase A to enhance its degradation.Small molecule therapeutics targeting F-box proteins in cancer.Ubiquitination-mediated degradation of cell cycle-related proteins by F-box proteinsA combinatorial F box protein directed pathway controls TRAF adaptor stability to regulate inflammation.New insights on the function of SCF ubiquitin E3 ligases in the lung.The emerging role of the ubiquitin proteasome in pulmonary biology and disease.Emerging therapies targeting the ubiquitin proteasome system in cancerFbxl12 triggers G1 arrest by mediating degradation of calmodulin kinase I.Low-intensity pulsed ultrasound (LIPUS) prevents periprosthetic inflammatory loosening through FBXL2-TRAF6 ubiquitination pathway.SCF ubiquitin ligase-targeted therapies.The ginsenoside metabolite compound K inhibits growth, migration and stemness of glioblastoma cells.Recent advances in SCF ubiquitin ligase complex: Clinical implicationsmiRNA-346 promotes proliferation, migration and invasion in liver cancer.F-box protein substrate recognition: a new insight.Chromatin-Bound Cullin-Ring Ligases: Regulatory Roles in DNA Replication and Potential Targeting for Cancer Therapy.
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P2860
F-box protein FBXL2 exerts human lung tumor suppressor-like activity by ubiquitin-mediated degradation of cyclin D3 resulting in cell cycle arrest
description
2012 nî lūn-bûn
@nan
2012 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի մայիսին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
F-box protein FBXL2 exerts hum ...... resulting in cell cycle arrest
@ast
F-box protein FBXL2 exerts hum ...... resulting in cell cycle arrest
@en
F-box protein FBXL2 exerts hum ...... resulting in cell cycle arrest
@nl
type
label
F-box protein FBXL2 exerts hum ...... resulting in cell cycle arrest
@ast
F-box protein FBXL2 exerts hum ...... resulting in cell cycle arrest
@en
F-box protein FBXL2 exerts hum ...... resulting in cell cycle arrest
@nl
prefLabel
F-box protein FBXL2 exerts hum ...... resulting in cell cycle arrest
@ast
F-box protein FBXL2 exerts hum ...... resulting in cell cycle arrest
@en
F-box protein FBXL2 exerts hum ...... resulting in cell cycle arrest
@nl
P2093
P2860
P356
P1433
P1476
F-box protein FBXL2 exerts hum ...... resulting in cell cycle arrest
@en
P2093
J R Glasser
R K Mallampalli
P2860
P2888
P304
P356
10.1038/ONC.2011.432
P407
P577
2012-05-17T00:00:00Z
P5875
P6179
1021190740