Toward the discovery of vaccine adjuvants: coupling in silico screening and in vitro analysis of antagonist binding to human and mouse CCR4 receptors
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Immunosuppressive Mechanisms of Malignant Gliomas: Parallels at Non-CNS SitesSrc homology 3-interacting domain of Rv1917c of Mycobacterium tuberculosis induces selective maturation of human dendritic cells by regulating PI3K-MAPK-NF-kappaB signaling and drives Th2 immune responsesStructural Analysis of Chemokine Receptor-Ligand Interactions.Current progress in Structure-Based Rational Drug Design marks a new mindset in drug discoveryEffect of Different Adjuvants on Protection and Side-Effects Induced by Helicobacter suis Whole-Cell Lysate Vaccination.Post-HTS case report and structural alert: Promiscuous 4-aroyl-1,5-disubstituted-3-hydroxy-2H-pyrrol-2-one actives verified by ALARM NMR.Comprehensive analysis of current approaches to inhibit regulatory T cells in cancer.Shifting the equilibrium in cancer immunoediting: from tumor tolerance to eradication.Regulatory T cells as adjuvant target for enhancing the viral disease vaccine efficacy.Pharmacological modulation of chemokine receptor function.Systematic identification of small molecule adjuvants.Targeting Tregs in Malignant Brain Cancer: Overcoming IDO.Harnessing the regulators to enhance viral vaccine efficacy.Chimeric antigen receptor modified T cells that target chemokine receptor CCR4 as a therapeutic modality for T-cell malignancies.The Yin and Yang of regulatory T cells in infectious diseases and avenues to target them.Diphtheria-toxin based anti-human CCR4 immunotoxin for targeting human CCR4(+) cells in vivo.Safety, tolerability, pharmacokinetics and pharmacodynamics of GSK2239633, a CC-chemokine receptor 4 antagonist, in healthy male subjects: results from an open-label and from a randomised study.Insights into the binding modes of CC chemokine receptor 4 (CCR4) inhibitors: a combined approach involving homology modelling, docking, and molecular dynamics simulation studies.The use of databases, data mining and immunoinformatics in vaccinology: where are we?A novel adjuvant, the mixture of alum and naltrexone, augments vaccine-induced immunity against Plasmodium berghei.In Silico Adjuvant Design and Validation.Maximal Unbiased Benchmarking Data Sets for Human Chemokine Receptors and Comparative Analysis.Chemokine axis as a therapeutic target to enhance the recruitment of Tregs and treat organ-specific autoimmune and inflammatory diseases
P2860
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P2860
Toward the discovery of vaccine adjuvants: coupling in silico screening and in vitro analysis of antagonist binding to human and mouse CCR4 receptors
description
2009 nî lūn-bûn
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2009 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Toward the discovery of vaccin ...... human and mouse CCR4 receptors
@ast
Toward the discovery of vaccin ...... human and mouse CCR4 receptors
@en
Toward the discovery of vaccin ...... human and mouse CCR4 receptors
@nl
type
label
Toward the discovery of vaccin ...... human and mouse CCR4 receptors
@ast
Toward the discovery of vaccin ...... human and mouse CCR4 receptors
@en
Toward the discovery of vaccin ...... human and mouse CCR4 receptors
@nl
prefLabel
Toward the discovery of vaccin ...... human and mouse CCR4 receptors
@ast
Toward the discovery of vaccin ...... human and mouse CCR4 receptors
@en
Toward the discovery of vaccin ...... human and mouse CCR4 receptors
@nl
P2093
P2860
P50
P1433
P1476
Toward the discovery of vaccin ...... human and mouse CCR4 receptors
@en
P2093
Darren R Flower
David F Tough
Emily K Forbes
Janakiraman Vani
Matthew N Davies
Melkote S Shaila
Peter C L Beverley
P2860
P356
10.1371/JOURNAL.PONE.0008084
P407
P577
2009-11-30T00:00:00Z