Network-based elucidation of human disease similarities reveals common functional modules enriched for pluripotent drug targets
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Gene-disease network analysis reveals functional modules in mendelian, complex and environmental diseasesLinked vaccine adverse event data from VAERS for biomedical data analysis and longitudinal studiesNetwork-based analysis of comorbidities risk during an infection: SARS and HIV case studiesNCBI GEO: archive for functional genomics data sets--10 years onEstablishing an analytic pipeline for genome-wide DNA methylationUnderstanding Genotype-Phenotype Effects in Cancer via Network ApproachesSystems Pharmacology in Small Molecular Drug DiscoveryComputational Models for Transplant Biomarker DiscoveryTranslational bioinformatics: linking the molecular world to the clinical worldStructure and dynamics of molecular networks: a novel paradigm of drug discovery: a comprehensive reviewThe emerging paradigm of network medicine in the study of human diseaseApplications of systems approaches in the study of rheumatic diseases.Using gene expression signatures to identify novel treatment strategies in gulf war illnessExploring off-targets and off-systems for adverse drug reactions via chemical-protein interactome--clozapine-induced agranulocytosis as a case studyDrug discovery using chemical systems biology: weak inhibition of multiple kinases may contribute to the anti-cancer effect of nelfinavirSystematic drug repositioning based on clinical side-effectsNetwork neighbors of drug targets contribute to drug side-effect similarityDrug target prediction and repositioning using an integrated network-based approachThe landscape of host transcriptional response programs commonly perturbed by bacterial pathogens: towards host-oriented broad-spectrum drug targetsSemFunSim: a new method for measuring disease similarity by integrating semantic and gene functional associationA network-based classification model for deriving novel drug-disease associations and assessing their molecular actionsThe human disease network in terms of dysfunctional regulatory mechanismsInferring drug-disease associations based on known protein complexesEvolutionary signatures amongst disease genes permit novel methods for gene prioritization and construction of informative gene-based networksA miRNA-driven inference model to construct potential drug-disease associations for drug repositioningApplications of translational bioinformatics in transplantationA physarum-inspired prize-collecting steiner tree approach to identify subnetworks for drug repositioningExplore Small Molecule-induced Genome-wide Transcriptional Profiles for Novel Inflammatory Bowel Disease DrugNetwork medicine: a network-based approach to human diseaseReconciling differential gene expression data with molecular interaction networksComputational drug repositioning: from data to therapeutics.Bioregulatory systems medicine: an innovative approach to integrating the science of molecular networks, inflammation, and systems biology with the patient's autoregulatory capacity?Inferring drug-disease associations from integration of chemical, genomic and phenotype data using network propagation.Refining gold from existing dataFusing literature and full network data improves disease similarity computation.Using Big Data to Discover Diagnostics and Therapeutics for Gastrointestinal and Liver Diseases.Integrating Clinical Phenotype and Gene Expression Data to Prioritize Novel Drug UsesUnraveling human protein interaction networks underlying co-occurrences of diseases and pathological conditions.Network mirroring for drug repositioningRIDDLE: reflective diffusion and local extension reveal functional associations for unannotated gene sets via proximity in a gene network.
P2860
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P2860
Network-based elucidation of human disease similarities reveals common functional modules enriched for pluripotent drug targets
description
2010 nî lūn-bûn
@nan
2010 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
Network-based elucidation of h ...... d for pluripotent drug targets
@ast
Network-based elucidation of h ...... d for pluripotent drug targets
@en
Network-based elucidation of h ...... d for pluripotent drug targets
@nl
type
label
Network-based elucidation of h ...... d for pluripotent drug targets
@ast
Network-based elucidation of h ...... d for pluripotent drug targets
@en
Network-based elucidation of h ...... d for pluripotent drug targets
@nl
prefLabel
Network-based elucidation of h ...... d for pluripotent drug targets
@ast
Network-based elucidation of h ...... d for pluripotent drug targets
@en
Network-based elucidation of h ...... d for pluripotent drug targets
@nl
P2093
P2860
P3181
P1476
Network-based elucidation of h ...... d for pluripotent drug targets
@en
P2093
Annie P Chiang
Joel T Dudley
Silpa Suthram
P2860
P304
P3181
P356
10.1371/JOURNAL.PCBI.1000662
P407
P577
2010-02-05T00:00:00Z