A sterol-regulatory element binding protein is required for cell polarity, hypoxia adaptation, azole drug resistance, and virulence in Aspergillus fumigatus - Wikidata - awgldk - TriplyDB

A sterol-regulatory element binding protein is required for cell polarity, hypoxia adaptation, azole drug resistance, and virulence in Aspergillus fumigatus

A sterol-regulatory element binding protein is required for cell polarity, hypoxia adaptation, azole drug resistance, and virulence in Aspergillus fumigatus

http://www.wikidata.org/entity/Q28473962

about

Pathogenesis of Aspergillus fumigatus in Invasive Aspergillosis Modulation of Host Angiogenesis as a Microbial Survival Strategy and Therapeutic Target Host pathogen relations: exploring animal models for fungal pathogens Hypoxia and fungal pathogenesis: to air or not to air?Sterol Biosynthesis and Azole Tolerance Is Governed by the Opposing Actions of SrbA and the CCAAT Binding Complex Transcriptional Control of Drug Resistance, Virulence and Immune System Evasion in Pathogenic Fungi: A Cross-Species Comparison The immune interplay between the host and the pathogen in Aspergillus fumigatus lung infection A Novel Zn2-Cys6 Transcription Factor AtrR Plays a Key Role in an Azole Resistance Mechanism of Aspergillus fumigatus by Co-regulating cyp51A and cdr1B Expressions SREBP coordinates iron and ergosterol homeostasis to mediate triazole drug and hypoxia responses in the human fungal pathogen Aspergillus fumigatus In vivo hypoxia and a fungal alcohol dehydrogenase influence the pathogenesis of invasive pulmonary aspergillosis Discovery of a HapE mutation that causes azole resistance in Aspergillus fumigatus through whole genome sequencing and sexual crossing Zinc finger transcription factors displaced SREBP proteins as the major Sterol regulators during Saccharomycotina evolution A novel sterol regulatory element-binding protein gene (sreA) identified in penicillium digitatum is required for prochloraz resistance, full virulence and erg11 (cyp51) regulation ChIP-seq and in vivo transcriptome analyses of the Aspergillus fumigatus SREBP SrbA reveals a new regulator of the fungal hypoxia response and virulence Alginate oligosaccharides inhibit fungal cell growth and potentiate the activity of antifungals against Candida and Aspergillus spp Characterization of the Paracoccidioides Hypoxia Response Reveals New Insights into Pathogenesis Mechanisms of This Important Human Pathogenic Fungus Mitochondrial Complex I Is a Global Regulator of Secondary Metabolism, Virulence and Azole Sensitivity in Fungi Sterol Regulatory Element Binding Protein (Srb1) Is Required for Hypoxic Adaptation and Virulence in the Dimorphic Fungus Histoplasma capsulatum Triazole Resistance in Aspergillus Species: An Emerging Problem.Regulation of hypoxia adaptation: an overlooked virulence attribute of pathogenic fungi?Microtubules are reversibly depolymerized in response to changing gaseous microenvironments within Aspergillus nidulans biofilms.Deciphering the Regulatory Network between the SREBP Pathway and Protein Secretion in Neurospora crassa.Aspergillus fumigatus Trehalose-Regulatory Subunit Homolog Moonlights To Mediate Cell Wall Homeostasis through Modulation of Chitin Synthase Activity.Genetic diversity and antifungal susceptibility profiles in causative agents of sporotrichosis.Filamentous fungal carbon catabolite repression supports metabolic plasticity and stress responses essential for disease progression.Functional analysis of two sterol regulatory element binding proteins in Penicillium digitatum Sterol regulatory element binding proteins in fungi: hypoxic transcription factors linked to pathogenesis Synergistic regulation of hyphal elongation by hypoxia, CO(2), and nutrient conditions controls the virulence of Candida albicans Comparative proteomic profiles of Aspergillus fumigatus and Aspergillus lentulus strains by surface-enhanced laser desorption ionization time-of-flight mass spectrometry (SELDI-TOF-MS)Cryptococcus neoformans Site-2 protease is required for virulence and survival in the presence of azole drugs HacA-independent functions of the ER stress sensor IreA synergize with the canonical UPR to influence virulence traits in Aspergillus fumigatus.Aspergillus fumigatus: contours of an opportunistic human pathogen.Regulatory interactions for iron homeostasis in Aspergillus fumigatus inferred by a Systems Biology approach Transcriptomic and proteomic analyses of the Aspergillus fumigatus hypoxia response using an oxygen-controlled fermenter.Fungal siderophore metabolism with a focus on Aspergillus fumigatus.Regulatory circuitry governing fungal development, drug resistance, and disease.Trehalose 6-phosphate phosphatase is required for cell wall integrity and fungal virulence but not trehalose biosynthesis in the human fungal pathogen Aspergillus fumigatus.Transcriptional and proteomic analysis of the Aspergillus fumigatus ΔprtT protease-deficient mutant.Myeloid derived hypoxia inducible factor 1-alpha is required for protection against pulmonary Aspergillus fumigatus infection The two-component sensor kinase TcsC and its role in stress resistance of the human-pathogenic mold Aspergillus fumigatus.

P2860

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P2860

A sterol-regulatory element binding protein is required for cell polarity, hypoxia adaptation, azole drug resistance, and virulence in Aspergillus fumigatus

http://www.wikidata.org/entity/Q28473962

description

2008 nî lūn-bûn

@nan

2008 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած

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2008 թվականի նոյեմբերին հրատարակված գիտական հոդված

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2008年の論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年論文

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2008年论文

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name

A sterol-regulatory element bi ...... lence in Aspergillus fumigatus

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A sterol-regulatory element bi ...... lence in Aspergillus fumigatus

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A sterol-regulatory element bi ...... lence in Aspergillus fumigatus

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A sterol-regulatory element bi ...... lence in Aspergillus fumigatus

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A sterol-regulatory element bi ...... lence in Aspergillus fumigatus

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JOURNAL.PPAT.1000200

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A sterol-regulatory element bi ...... lence in Aspergillus fumigatus

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Christopher B Lawrence

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James B Burritt

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Kwang-Hyung Kim

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Laurel J Metzler

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Martin Bard

http://www.w3.org/2001/XMLSchema#string

Nora Grahl

http://www.w3.org/2001/XMLSchema#string

Robert A Cramer

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Robert Barbuch

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Srisombat Puttikamonkul

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P2860

Genomic sequence of the pathogenic and allergenic filamentous fungus Aspergillus fumigatus

Crucial step in cholesterol homeostasis: sterols promote binding of SCAP to INSIG-1, a membrane protein that facilitates retention of SREBPs in ER

Significance analysis of microarrays applied to the ionizing radiation response

LaeA, a regulator of secondary metabolism in Aspergillus spp

Aspergillus fumigatus: principles of pathogenesis and host defense

Oxygenation inhibits the physiological tissue-protecting mechanism and thereby exacerbates acute inflammatory lung injury.

The use of lead citrate at high pH as an electron-opaque stain in electron microscopy

Identification of a UPC2 homolog in Saccharomyces cerevisiae and its involvement in aerobic sterol uptake

Characterization of the Saccharomyces cerevisiae ERG27 gene encoding the 3-keto reductase involved in C-4 sterol demethylation.

A role for sterol levels in oxygen sensing in Saccharomyces cerevisiae.

P304

e1000200

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scholarly article

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693737

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10.1371/JOURNAL.PPAT.1000200

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11

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4

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2008-11-01T00:00:00Z

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23456672

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18989462

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P921

Aspergillus fumigatus

protein of unknown function

Putative c-14 sterol reductase with a predicted role in ergosterol biosynthesis

Putative oxidoreductase, short chain dehydrogenase/reductase family member

Putative GPI-anchored protein

Non-ribosomal peptide synthetase (NRPS)

Putative ABC multidrug transporter

Putative transporter protein

P932

2572145

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