Identification of three classes of heteroaromatic compounds with activity against intracellular Trypanosoma cruzi by chemical library screening
about
Next-generation antimicrobials: from chemical biology to first-in-class drugsAntitrypanosomal Lead Discovery: Identification of a Ligand-Efficient Inhibitor of Trypanosoma cruzi CYP51 and Parasite GrowthIn vitro and in vivo high-throughput assays for the testing of anti-Trypanosoma cruzi compoundsSoulamarin isolated from Calophyllum brasiliense (Clusiaceae) induces plasma membrane permeabilization of Trypanosoma cruzi and mytochondrial dysfunctionHigh throughput screening for anti-Trypanosoma cruzi drug discoveryAutomated high-content assay for compounds selectively toxic to Trypanosoma cruzi in a myoblastic cell lineMachine Learning Models and Pathway Genome Data Base for Trypanosoma cruzi Drug DiscoveryIdentification of Trypanocidal Activity for Known Clinical Compounds Using a New Trypanosoma cruzi Hit-Discovery Screening Cascade.Bigger data, collaborative tools and the future of predictive drug discoveryNew compound sets identified from high throughput phenotypic screening against three kinetoplastid parasites: an open resource.Image-based high-throughput drug screening targeting the intracellular stage of Trypanosoma cruzi, the agent of Chagas' disease.Diversity-oriented synthesis yields a new drug lead for treatment of chagas diseaseErgosterol isolated from the basidiomycete Pleurotus salmoneostramineus affects Trypanosoma cruzi plasma membrane and mitochondria.Methodological advances in drug discovery for Chagas disease.Arylimidamide DB766, a potential chemotherapeutic candidate for Chagas' disease treatmentDrug strategies targeting CYP51 in neglected tropical diseasesHigh-throughput screening platform for natural product-based drug discovery against 3 neglected tropical diseases: human African trypanosomiasis, leishmaniasis, and Chagas disease.Advances in Chagas disease drug development: 2009-2010Chagas disease drug discovery: toward a new era.Report of the 2nd Chagas Drug Discovery Consortium meeting, held on 3 November 2010; Atlanta GA, USA.Selection and optimization of hits from a high-throughput phenotypic screen against Trypanosoma cruzi.Design, development, and validation of a high-throughput drug-screening assay for targeting of human leukemia3-Hydroxykynurenine, a Tryptophan Metabolite Generated during the Infection, Is Active Against Trypanosoma cruzi.In vitro and in vivo experimental models for drug screening and development for Chagas disease.Computational models for neglected diseases: gaps and opportunities.Phenotypic screening approaches for Chagas disease drug discovery.Synthesis and Biological Activity of Sterol 14α-Demethylase and Sterol C24-Methyltransferase Inhibitors
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P2860
Identification of three classes of heteroaromatic compounds with activity against intracellular Trypanosoma cruzi by chemical library screening
description
2009 nî lūn-bûn
@nan
2009 թուականին հրատարակուած գիտական յօդուած
@hyw
2009 թվականին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Identification of three classe ...... by chemical library screening
@ast
Identification of three classe ...... by chemical library screening
@en
Identification of three classe ...... by chemical library screening
@nl
type
label
Identification of three classe ...... by chemical library screening
@ast
Identification of three classe ...... by chemical library screening
@en
Identification of three classe ...... by chemical library screening
@nl
prefLabel
Identification of three classe ...... by chemical library screening
@ast
Identification of three classe ...... by chemical library screening
@en
Identification of three classe ...... by chemical library screening
@nl
P2093
P2860
P3181
P1476
Identification of three classe ...... by chemical library screening
@en
P2093
Esther Bettiol
Frederick Buckner
Jayne Raper
Marie Samanovic
P2860
P3181
P356
10.1371/JOURNAL.PNTD.0000384
P407
P577
2009-01-01T00:00:00Z