Regulation of PERK signaling and leukemic cell survival by a novel cytosolic isoform of the UPR regulator GRP78/BiP
about
Regulation of AKT phosphorylation at Ser473 and Thr308 by endoplasmic reticulum stress modulates substrate specificity in a severity dependent mannerp58IPK is an inhibitor of the eIF2α kinase GCN2 and its localization and expression underpin protein synthesis and ER processing capacityIdentification of a potential tumor differentiation factor receptor candidate in prostate cancer cellsCap-Independent Translation in Hematological MalignanciesGRP94: An HSP90-like protein specialized for protein folding and quality control in the endoplasmic reticulumModulation of the Akt pathway reveals a novel link with PERK/eIF2α, which is relevant during hypoxiaHeat shock proteins: cellular and molecular mechanisms in the central nervous system.Protective unfolded protein response in human pancreatic beta cells transplanted into mice.The Par-4-GRP78 TRAIL, more twists and turns.Cell surface relocalization of the endoplasmic reticulum chaperone and unfolded protein response regulator GRP78/BiP.In search of the identity of the XAP-1 antigen: a protein localized to cone outer segments.The endoplasmic reticulum chaperone protein GRP94 is required for maintaining hematopoietic stem cell interactions with the adult bone marrow niche.Acute inducible ablation of GRP78 reveals its role in hematopoietic stem cell survival, lymphogenesis and regulation of stress signaling.Characterization of tumor differentiation factor (TDF) and its receptor (TDF-R).The 3' UTR variants in the GRP78 are not associated with overall survival in resectable hepatocellular carcinoma.Identification of an intrinsic determinant critical for maspin subcellular localization and function.Novel mechanism of anti-apoptotic function of 78-kDa glucose-regulated protein (GRP78): endocrine resistance factor in breast cancer, through release of B-cell lymphoma 2 (BCL-2) from BCL-2-interacting killer (BIK).E6^E7, a novel splice isoform protein of human papillomavirus 16, stabilizes viral E6 and E7 oncoproteins via HSP90 and GRP78.GRP78-directed immunotherapy in relapsed or refractory multiple myeloma - results from a phase 1 trial with the monoclonal immunoglobulin M antibody PAT-SM6.Characterization and mechanism of stress-induced translocation of 78-kilodalton glucose-regulated protein (GRP78) to the cell surface.A review of the mammalian unfolded protein response.The expression of the endoplasmic reticulum stress sensor BiP/GRP78 predicts response to chemotherapy and determines the efficacy of proteasome inhibitors in diffuse large b-cell lymphomaPML-RARα enhances constitutive autophagic activity through inhibiting the Akt/mTOR pathway.Inducible knockout of GRP78/BiP in the hematopoietic system suppresses Pten-null leukemogenesis and AKT oncogenic signalingIdentification of potential tumor differentiation factor (TDF) receptor from steroid-responsive and steroid-resistant breast cancer cells.Beyond the endoplasmic reticulum: atypical GRP78 in cell viability, signalling and therapeutic targetingClass I histone deacetylases localize to the endoplasmic reticulum and modulate the unfolded protein response.Selective loss of RPGRIP1-dependent ciliary targeting of NPHP4, RPGR and SDCCAG8 underlies the degeneration of photoreceptor neuronsGRP78 plays an essential role in adipogenesis and postnatal growth in mice.Probing novel roles of the mitochondrial uniporter in ovarian cancer cells using nanoparticlesThe critical roles of endoplasmic reticulum chaperones and unfolded protein response in tumorigenesis and anticancer therapiesEndoplasmic reticulum stress: its role in disease and novel prospects for therapy.Discovery of a novel target for the dysglycemic chromogranin A fragment pancreastatin: interaction with the chaperone GRP78 to influence metabolism.Plumbagin sensitizes breast cancer cells to tamoxifen-induced cell death through GRP78 inhibition and Bik upregulation.Role of Glycosylation/Deglycolysation Processes in Francisella tularensis Pathogenesis.GRP78 as a regulator of liver steatosis and cancer progression mediated by loss of the tumor suppressor PTEN.Ca2+-signaling, alternative splicing and endoplasmic reticulum stress responses.The Molecular Chaperone GRP78/BiP in the Development of Chemoresistance: Mechanism and Possible Treatment.Regulatory crosstalk within the mammalian unfolded protein response.Glucose-regulated proteins in cancer: molecular mechanisms and therapeutic potential
P2860
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P2860
Regulation of PERK signaling and leukemic cell survival by a novel cytosolic isoform of the UPR regulator GRP78/BiP
description
2009 nî lūn-bûn
@nan
2009 թուականի Օգոստոսին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի օգոստոսին հրատարակված գիտական հոդված
@hy
2009年の論文
@ja
2009年論文
@yue
2009年論文
@zh-hant
2009年論文
@zh-hk
2009年論文
@zh-mo
2009年論文
@zh-tw
2009年论文
@wuu
name
Regulation of PERK signaling a ...... of the UPR regulator GRP78/BiP
@ast
Regulation of PERK signaling a ...... of the UPR regulator GRP78/BiP
@en
Regulation of PERK signaling a ...... of the UPR regulator GRP78/BiP
@nl
type
label
Regulation of PERK signaling a ...... of the UPR regulator GRP78/BiP
@ast
Regulation of PERK signaling a ...... of the UPR regulator GRP78/BiP
@en
Regulation of PERK signaling a ...... of the UPR regulator GRP78/BiP
@nl
prefLabel
Regulation of PERK signaling a ...... of the UPR regulator GRP78/BiP
@ast
Regulation of PERK signaling a ...... of the UPR regulator GRP78/BiP
@en
Regulation of PERK signaling a ...... of the UPR regulator GRP78/BiP
@nl
P2093
P2860
P3181
P1433
P1476
Regulation of PERK signaling a ...... of the UPR regulator GRP78/BiP
@en
P2093
Peter Baumeister
Shiuan Wey
P2860
P3181
P356
10.1371/JOURNAL.PONE.0006868
P407
P50
P577
2009-08-31T00:00:00Z