A molecular mechanism for eflornithine resistance in African trypanosomes
about
Management of trypanosomiasis and leishmaniasisThe ever unfolding story of cAMP signaling in trypanosomatids: vive la difference!Drug repurposing and human parasitic protozoan diseasesRecent developments in drug discovery for leishmaniasis and human African trypanosomiasisNew Approaches to Overcome Transport Related Drug Resistance in Trypanosomatid ParasitesUntargeted metabolomics reveals a lack of synergy between nifurtimox and eflornithine against Trypanosoma bruceiAquaporin 2 mutations in Trypanosoma brucei gambiense field isolates correlate with decreased susceptibility to pentamidine and melarsoprolProline modulates the Trypanosoma cruzi resistance to reactive oxygen species and drugs through a novel D, L-proline transporterSpecific Cell Targeting Therapy Bypasses Drug Resistance Mechanisms in African TrypanosomiasisAn Atypical Mitochondrial Carrier That Mediates Drug Action in Trypanosoma bruceiGenomic and Proteomic Studies on the Mode of Action of Oxaboroles against the African TrypanosomeReduced Mitochondrial Membrane Potential Is a Late Adaptation of Trypanosoma brucei brucei to Isometamidium Preceded by Mutations in the γ Subunit of the F1Fo-ATPaseTransport proteins determine drug sensitivity and resistance in a protozoan parasite, Trypanosoma bruceiDrug resistance in eukaryotic microorganisms.Genome-wide RNAi screens in African trypanosomes identify the nifurtimox activator NTR and the eflornithine transporter AAT6.The threonine degradation pathway of the Trypanosoma brucei procyclic form: the main carbon source for lipid biosynthesis is under metabolic control.Whole-organism high-throughput screening against Trypanosoma brucei brucei.Genetic dissection of drug resistance in trypanosomesHigh-throughput decoding of drug targets and drug resistance mechanisms in African trypanosomes.Trypanocidal furamidine analogues: influence of pyridine nitrogens on trypanocidal activity, transport kinetics, and resistance patterns.Discovery of an ergosterol-signaling factor that regulates Trypanosoma brucei growthAntiparasitic chemotherapy: from genomes to mechanisms.The molecular dynamics of Trypanosoma brucei UDP-galactose 4'-epimerase: a drug target for African sleeping sicknessCell Surface Proteomics Provides Insight into Stage-Specific Remodeling of the Host-Parasite Interface in Trypanosoma bruceiThe Role of Folate Transport in Antifolate Drug Action in Trypanosoma brucei.Arginine and Lysine Transporters Are Essential for Trypanosoma bruceiMulticomponent reaction-based synthesis and biological evaluation of tricyclic heterofused quinolines with multi-trypanosomatid activityGlobal metabolic analyses identify key differences in metabolite levels between polymyxin-susceptible and polymyxin-resistant Acinetobacter baumannii.Induced resistance to methionyl-tRNA synthetase inhibitors in Trypanosoma brucei is due to overexpression of the target.Whole-genome sequencing of Trypanosoma brucei reveals introgression between subspecies that is associated with virulence.Comparative genomics of drug resistance in Trypanosoma brucei rhodesiense.Drug resistance in African trypanosomiasis: the melarsoprol and pentamidine story.Green fluorescent diamidines as diagnostic probes for trypanosomes.Development of novel drugs for human African trypanosomiasis.Drug resistance in human African trypanosomiasis.Update on field use of the available drugs for the chemotherapy of human African trypanosomiasis.Determination of antiprotozoal drug mechanisms by metabolomics approaches.Metabolomic-based strategies for anti-parasite drug discovery.Nitroheterocyclic drug resistance mechanisms in Trypanosoma brucei.Functional analysis of drug resistance-associated mutations in the Trypanosoma brucei adenosine transporter 1 (TbAT1) and the proposal of a structural model for the protein.
P2860
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P2860
A molecular mechanism for eflornithine resistance in African trypanosomes
description
2010 nî lūn-bûn
@nan
2010 թուականի Նոյեմբերին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի նոյեմբերին հրատարակված գիտական հոդված
@hy
2010年の論文
@ja
2010年論文
@yue
2010年論文
@zh-hant
2010年論文
@zh-hk
2010年論文
@zh-mo
2010年論文
@zh-tw
2010年论文
@wuu
name
A molecular mechanism for eflornithine resistance in African trypanosomes
@ast
A molecular mechanism for eflornithine resistance in African trypanosomes
@en
A molecular mechanism for eflornithine resistance in African trypanosomes
@nl
type
label
A molecular mechanism for eflornithine resistance in African trypanosomes
@ast
A molecular mechanism for eflornithine resistance in African trypanosomes
@en
A molecular mechanism for eflornithine resistance in African trypanosomes
@nl
prefLabel
A molecular mechanism for eflornithine resistance in African trypanosomes
@ast
A molecular mechanism for eflornithine resistance in African trypanosomes
@en
A molecular mechanism for eflornithine resistance in African trypanosomes
@nl
P2093
P2860
P50
P921
P3181
P1433
P1476
A molecular mechanism for eflornithine resistance in African trypanosomes
@en
P2093
David G Watson
Debra J Woods
Mohammed A Kamleh
Pui Ee Wong
P2860
P304
P3181
P356
10.1371/JOURNAL.PPAT.1001204
P407
P577
2010-11-24T00:00:00Z