Apolipoprotein E: isoform specific differences in tertiary structure and interaction with amyloid-β in human Alzheimer brain
about
Interactions of metals and Apolipoprotein E in Alzheimer's diseaseImpact of apolipoprotein E on Alzheimer's diseaseApolipoprotein E: from cardiovascular disease to neurodegenerative disordersApolipoprotein E isoforms and regulation of the innate immune response in brain of patients with Alzheimer's diseaseFörster resonance energy transfer microscopy and spectroscopy for localizing protein-protein interactions in living cells.Molecular basis for increased risk for late-onset Alzheimer disease due to the naturally occurring L28P mutation in apolipoprotein E4.Apolipoprotein E: structure and function in lipid metabolism, neurobiology, and Alzheimer's diseases.Extracellular proteolysis of apolipoprotein E (apoE) by secreted serine neuronal proteaseAn apolipoprotein E4 fragment affects matrix metalloproteinase 9, tissue inhibitor of metalloproteinase 1 and cytokine levels in brain cell lines.Apolipoprotein E4 effects in Alzheimer's disease are mediated by synaptotoxic oligomeric amyloid-βReducing human apolipoprotein E levels attenuates age-dependent Aβ accumulation in mutant human amyloid precursor protein transgenic mice.Apolipoprotein E, especially apolipoprotein E4, increases the oligomerization of amyloid β peptide.Apolipoprotein E, amyloid-ß clearance and therapeutic opportunities in Alzheimer's diseaseAPOE4-specific changes in Aβ accumulation in a new transgenic mouse model of Alzheimer disease.Levels of soluble apolipoprotein E/amyloid-β (Aβ) complex are reduced and oligomeric Aβ increased with APOE4 and Alzheimer disease in a transgenic mouse model and human samplesApolipoprotein e sets the stage: response to injury triggers neuropathology.Association of plasma and cortical amyloid beta is modulated by APOE ε4 statusThe ability of apolipoprotein E fragments to promote intraneuronal accumulation of amyloid beta peptide 42 is both isoform and size-specific.Lipid Processing in the Brain: A Key Regulator of Systemic Metabolism.Actin dynamics and cofilin-actin rods in alzheimer disease.HtrA1 Proteolysis of ApoE In Vitro Is Allele Selective.IL-10 alters immunoproteostasis in APP mice, increasing plaque burden and worsening cognitive behavior.Apolipoprotein e: essential catalyst of the Alzheimer amyloid cascade.Iron Regulates Apolipoprotein E Expression and Secretion in Neurons and Astrocytes.Flow Cytometry Analysis and Quantitative Characterization of Tau in Synaptosomes from Alzheimer's Disease Brains.APOE2 enhances neuroprotection against Alzheimer's disease through multiple molecular mechanisms.Isoform- and cell type-specific structure of apolipoprotein E lipoparticles as revealed by a novel Forster resonance energy transfer assay.Endogenous Apolipoprotein E (ApoE) Fragmentation Is Linked to Amyloid Pathology in Transgenic Mouse Models of Alzheimer's Disease.
P2860
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P2860
Apolipoprotein E: isoform specific differences in tertiary structure and interaction with amyloid-β in human Alzheimer brain
description
2011 nî lūn-bûn
@nan
2011 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հունվարին հրատարակված գիտական հոդված
@hy
2011年の論文
@ja
2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
@wuu
name
Apolipoprotein E: isoform spec ...... oid-β in human Alzheimer brain
@ast
Apolipoprotein E: isoform spec ...... oid-β in human Alzheimer brain
@en
Apolipoprotein E: isoform spec ...... oid-β in human Alzheimer brain
@nl
type
label
Apolipoprotein E: isoform spec ...... oid-β in human Alzheimer brain
@ast
Apolipoprotein E: isoform spec ...... oid-β in human Alzheimer brain
@en
Apolipoprotein E: isoform spec ...... oid-β in human Alzheimer brain
@nl
prefLabel
Apolipoprotein E: isoform spec ...... oid-β in human Alzheimer brain
@ast
Apolipoprotein E: isoform spec ...... oid-β in human Alzheimer brain
@en
Apolipoprotein E: isoform spec ...... oid-β in human Alzheimer brain
@nl
P2093
P2860
P3181
P1433
P1476
Apolipoprotein E: isoform spec ...... oid-β in human Alzheimer brain
@en
P2093
Anete Rozkalne
Brian J Bacskai
Christine A F von Armin
Kenneth W Adams
Mathew Mielke
Phillip B Jones
Tadafumi Hashimoto
Tammy T Hshieh
P2860
P304
P3181
P356
10.1371/JOURNAL.PONE.0014586
P407
P577
2011-01-31T00:00:00Z