A screen against Leishmania intracellular amastigotes: comparison to a promastigote screen and identification of a host cell-specific hit
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Kinases as druggable targets in trypanosomatid protozoan parasitesRecent developments in drug discovery for leishmaniasis and human African trypanosomiasisAn image-based high-content screening assay for compounds targeting intracellular Leishmania donovani amastigotes in human macrophagesNaloxonazine, an Amastigote-Specific Compound, Affects Leishmania Parasites through Modulation of Host-Encoded FunctionsIdentification of new antileishmanial leads from hits obtained by high-throughput screeningIn vitro and in vivo activity of an organic tellurium compound on Leishmania (Leishmania) chagasiAppraisal of a Leishmania major strain stably expressing mCherry fluorescent protein for both in vitro and in vivo studies of potential drugs and vaccine against cutaneous leishmaniasisHigh content analysis of primary macrophages hosting proliferating Leishmania amastigotes: application to anti-leishmanial drug discoveryExploring anti-bacterial compounds against intracellular LegionellaMiltefosine and antimonial drug susceptibility of Leishmania Viannia species and populations in regions of high transmission in ColombiaAn image-based algorithm for precise and accurate high throughput assessment of drug activity against the human parasite Trypanosoma cruziHigh throughput screening for anti-Trypanosoma cruzi drug discoveryUsing a non-image-based medium-throughput assay for screening compounds targeting N-myristoylation in intracellular Leishmania amastigotesDevelopment and Validation of a Novel Leishmania donovani Screening Cascade for High-Throughput Screening Using a Novel Axenic Assay with High Predictivity of Leishmanicidal Intracellular Activity.Drug discovery algorithm for cutaneous leishmaniasis.Antileishmanial Activity of Compounds Derived from the Medicines for Malaria Venture Open Access Box Against Intracellular Leishmania major AmastigotesThe establishment of in vitro culture and drug screening systems for a newly isolated strain of Trypanosoma equiperdum.A novel Leishmania major amastigote assay in 96-well format for rapid drug screening and its use for discovery and evaluation of a new class of leishmanicidal quinolinium salts.Design and synthesis of novel antileishmanial compounds.EVALUATION OF AROMATIC 6-SUBSTITUTED THIENOPYRIMIDINES AS SCAFFOLDS AGAINST PARASITES THAT CAUSE TRYPANOSOMIASIS, LEISHMANIASIS, AND MALARIA.Protozoan Parasite Growth Inhibitors Discovered by Cross-Screening Yield Potent Scaffolds for Lead Discovery.Coxiella burnetii and Leishmania mexicana residing within similar parasitophorous vacuoles elicit disparate host responsesImaging flow cytometry analysis of intracellular pathogens.Cytotoxicity and In Vitro Antileishmanial Activity of Antimony (V), Bismuth (V), and Tin (IV) Complexes of Lapachol.A Replicative In Vitro Assay for Drug Discovery against Leishmania donovaniAn alternative in vitro drug screening test using Leishmania amazonensis transfected with red fluorescent protein.Pharmacological assessment defines Leishmania donovani casein kinase 1 as a drug target and reveals important functions in parasite viability and intracellular infection.Automated imaging and other developments in whole-organism anthelmintic screening.Imaging host-Leishmania interactions: significance in visceral leishmaniasis.Visceral leishmaniasis treatment: What do we have, what do we need and how to deliver it?Antileishmanial activity of some Brazilian plants, with particular reference to Casearia sylvestris.Repurposing as a strategy for the discovery of new anti-leishmanials: the-state-of-the-art.Comparison of a high-throughput high-content intracellular Leishmania donovani assay with an axenic amastigote assay.Simple colorimetric trypanothione reductase-based assay for high-throughput screening of drugs against Leishmania intracellular amastigotes.Antileishmanial activity and evaluation of the mechanism of action of strychnobiflavone flavonoid isolated from Strychnos pseudoquina against Leishmania infantum.Synthesis of 16 New Hybrids from Tetrahydropyrans Derivatives and Morita-Baylis-Hillman Adducts: In Vitro Screening against Leishmania donovani.Repurposing human Aurora kinase inhibitors as leads for anti-protozoan drug discovery.Insights into the structural patterns of the antileishmanial activity of bi- and tricyclic N-heterocycles.Development of a semi-automated image-based high-throughput drug screening system.Marine Algae as Source of Novel Antileishmanial Drugs: A Review.
P2860
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P2860
A screen against Leishmania intracellular amastigotes: comparison to a promastigote screen and identification of a host cell-specific hit
description
2011 nî lūn-bûn
@nan
2011 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2011 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
2011年の論文
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2011年論文
@yue
2011年論文
@zh-hant
2011年論文
@zh-hk
2011年論文
@zh-mo
2011年論文
@zh-tw
2011年论文
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name
A screen against Leishmania in ...... on of a host cell-specific hit
@ast
A screen against Leishmania in ...... on of a host cell-specific hit
@en
A screen against Leishmania in ...... on of a host cell-specific hit
@nl
type
label
A screen against Leishmania in ...... on of a host cell-specific hit
@ast
A screen against Leishmania in ...... on of a host cell-specific hit
@en
A screen against Leishmania in ...... on of a host cell-specific hit
@nl
prefLabel
A screen against Leishmania in ...... on of a host cell-specific hit
@ast
A screen against Leishmania in ...... on of a host cell-specific hit
@en
A screen against Leishmania in ...... on of a host cell-specific hit
@nl
P2093
P2860
P1476
A screen against Leishmania in ...... on of a host cell-specific hit
@en
P2093
Geraldine De Muylder
Juan C Engel
Kenny K H Ang
Michelle R Arkin
Steven Chen
P2860
P356
10.1371/JOURNAL.PNTD.0001253
P407
P5008
P577
2011-07-01T00:00:00Z