New insights into fluoroquinolone resistance in Mycobacterium tuberculosis: functional genetic analysis of gyrA and gyrB mutations
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Clinical use of whole genome sequencing for Mycobacterium tuberculosisEvolution of drug resistance in tuberculosis: recent progress and implications for diagnosis and therapyFirst evaluation of drug-resistant Mycobacterium tuberculosis clinical isolates from Congo revealed misdetection of fluoroquinolone resistance by line probe assay due to a double substitution T80A-A90G in GyrAFrequency and geographic distribution of gyrA and gyrB mutations associated with fluoroquinolone resistance in clinical Mycobacterium tuberculosis isolates: a systematic reviewA Comparison of the Sensititre MycoTB Plate, the Bactec MGIT 960, and a Microarray-Based Molecular Assay for the Detection of Drug Resistance in Clinical Mycobacterium tuberculosis Isolates in Moscow, RussiaIntegrated microfluidic card with TaqMan probes and high-resolution melt analysis to detect tuberculosis drug resistance mutations across 10 genes.Four decades of transmission of a multidrug-resistant Mycobacterium tuberculosis outbreak strainAlignment of new tuberculosis drug regimens and drug susceptibility testing: a framework for actionEarly detection of multidrug- and pre-extensively drug-resistant tuberculosis from smear-positive sputum by direct sequencing.A Multinational Analysis of Mutations and Heterogeneity in PZase, RpsA, and PanD Associated with Pyrazinamide Resistance in M/XDR Mycobacterium tuberculosis.Moxifloxacin resistance in the F15/LAM4/KZN extensively drug-resistant strain of Mycobacterium tuberculosis.Detection of second-line drug resistance in Mycobacterium tuberculosis using oligonucleotide microarrays.GWAMAR: genome-wide assessment of mutations associated with drug resistance in bacteria.Industrial robustness: understanding the mechanism of tolerance for the Populus hydrolysate-tolerant mutant strain of Clostridium thermocellumMolecular diagnosis of fluoroquinolone resistance in Mycobacterium tuberculosis.Clinical application of whole-genome sequencing to inform treatment for multidrug-resistant tuberculosis cases.Rapid determination of anti-tuberculosis drug resistance from whole-genome sequencesDiagnostic Performance of the New Version (v2.0) of GenoType MTBDRsl Assay for Detection of Resistance to Fluoroquinolones and Second-Line Injectable Drugs: a Multicenter StudyCorrelation between GyrA substitutions and ofloxacin, levofloxacin, and moxifloxacin cross-resistance in Mycobacterium tuberculosis.Delamanid susceptibility testing of Mycobacterium tuberculosis using the resazurin microtitre assay and the BACTEC™ MGIT™ 960 system.Importance of the genetic diversity within the Mycobacterium tuberculosis complex for the development of novel antibiotics and diagnostic tests of drug resistanceGyrase Mutations Are Associated with Variable Levels of Fluoroquinolone Resistance in Mycobacterium tuberculosisCorrelation of different phenotypic drug susceptibility testing methods for four fluoroquinolones in Mycobacterium tuberculosis.Performance of the New Version (v2.0) of the GenoType MTBDRsl Test for Detection of Resistance to Second-Line Drugs in Multidrug-Resistant Mycobacterium tuberculosis Complex Strains.Impact of fluoroquinolone resistance on bactericidal and sterilizing activity of a moxifloxacin-containing regimen in murine tuberculosis.Evaluation of MTBDRplus and MTBDRsl in Detecting Drug-Resistant Tuberculosis in a Chinese Population.Fluoroquinolone susceptibility in Mycobacterium tuberculosis after pre-diagnosis exposure to older- versus newer-generation fluoroquinolones.Wild-Type and Non-Wild-Type Mycobacterium tuberculosis MIC Distributions for the Novel Fluoroquinolone Antofloxacin Compared with Those for Ofloxacin, Levofloxacin, and MoxifloxacinRole of gyrB Mutations in Pre-extensively and Extensively Drug-Resistant Tuberculosis in Thai Clinical IsolatesSequence Analysis of Fluoroquinolone Resistance-Associated Genes gyrA and gyrB in Clinical Mycobacterium tuberculosis Isolates from Patients Suspected of Having Multidrug-Resistant Tuberculosis in New Delhi, India.Genomic Analysis of the Evolution of Fluoroquinolone Resistance in Mycobacterium tuberculosis Prior to Tuberculosis Diagnosis.Systematic review of allelic exchange experiments aimed at identifying mutations that confer drug resistance in Mycobacterium tuberculosis.Prevalence and molecular characterization of fluoroquinolone-resistant Mycobacterium tuberculosis isolates in China.Evidence of Clonal Expansion in the Genome of a Multidrug-Resistant Mycobacterium tuberculosis Clinical Isolate from Peru.Association of gyrA/B mutations and resistance levels to fluoroquinolones in clinical isolates of Mycobacterium tuberculosis.Some Synonymous and Nonsynonymous gyrA Mutations in Mycobacterium tuberculosis Lead to Systematic False-Positive Fluoroquinolone Resistance Results with the Hain GenoType MTBDRsl Assays.Fighting an old disease with modern tools: characteristics and molecular detection methods of drug-resistant Mycobacterium tuberculosis.Plasmid-based controls to detect rpoB mutations in Mycobacterium tuberculosis by quantitative polymerase chain reaction-high-resolution melting.Impact of gyrB and eis Mutations in Improving Detection of Second-Line-Drug Resistance among Mycobacterium tuberculosis Isolates from Georgia.Double mutation in DNA gyrase confers moxifloxacin resistance and decreased fitness of Mycobacterium smegmatis.
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P2860
New insights into fluoroquinolone resistance in Mycobacterium tuberculosis: functional genetic analysis of gyrA and gyrB mutations
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2012 nî lūn-bûn
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2012 թուականին հրատարակուած գիտական յօդուած
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2012 թվականին հրատարակված գիտական հոդված
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2012年の論文
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2012年学术文章
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2012年学术文章
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2012年学术文章
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2012年学术文章
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2012年学术文章
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2012年學術文章
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name
New insights into fluoroquinol ...... sis of gyrA and gyrB mutations
@ast
New insights into fluoroquinol ...... sis of gyrA and gyrB mutations
@en
New insights into fluoroquinol ...... sis of gyrA and gyrB mutations
@nl
type
label
New insights into fluoroquinol ...... sis of gyrA and gyrB mutations
@ast
New insights into fluoroquinol ...... sis of gyrA and gyrB mutations
@en
New insights into fluoroquinol ...... sis of gyrA and gyrB mutations
@nl
prefLabel
New insights into fluoroquinol ...... sis of gyrA and gyrB mutations
@ast
New insights into fluoroquinol ...... sis of gyrA and gyrB mutations
@en
New insights into fluoroquinol ...... sis of gyrA and gyrB mutations
@nl
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New insights into fluoroquinol ...... sis of gyrA and gyrB mutations
@en
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David Sikes
James E Posey
Melisa Willby
Oleg V Tsodikov
Seidu Malik
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P304
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P356
10.1371/JOURNAL.PONE.0039754
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P577
2012-01-01T00:00:00Z