Anthrax lethal factor cleavage of Nlrp1 is required for activation of the inflammasome
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Tumor Targeting and Drug Delivery by Anthrax ToxinHow Mouse Macrophages Sense What Is Going On.Bacterial Toxins as Pathogen Weapons Against PhagocytesBacterial Exotoxins and the InflammasomeCrossing of the epithelial barriers by Bacillus anthracis: the Known and the UnknownA Nod to disease vectors: mitigation of pathogen sensing by arthropod salivaAnthrax lethal and edema toxins in anthrax pathogenesisOf inflammasomes and pathogens--sensing of microbes by the inflammasomeAn Update on PYRIN Domain-Containing Pattern Recognition Receptors: From Immunity to PathologyPolicing the cytosol--bacterial-sensing inflammasome receptors and pathwaysBeyond pattern recognition: NOD-like receptors in dendritic cells.Integrating Inflammasome Signaling in Sexually Transmitted InfectionsInternational Union of Basic and Clinical Pharmacology. XCVI. Pattern recognition receptors in health and diseaseCCT chaperonin complex is required for efficient delivery of anthrax toxin into the cytosol of host cellsActivation of the Nlrp1b inflammasome by reduction of cytosolic ATPNLRP1-dependent pyroptosis leads to acute lung injury and morbidity in miceActivation and regulation of the inflammasomesToxin inhibition of antimicrobial factors induced by Bacillus anthracis peptidoglycan in human blood.Key tissue targets responsible for anthrax-toxin-induced lethality.Channel-forming bacterial toxins in biosensing and macromolecule deliveryDistinct regions of NLRP1B are required to respond to anthrax lethal toxin and metabolic inhibition.Both lethal and edema toxins of Bacillus anthracis disrupt the human dendritic cell chemokine network.Small molecule inhibitors of Bacillus anthracis protective antigen proteolytic activation and oligomerization.Anthrax lethal factor cleaves mouse nlrp1b in both toxin-sensitive and toxin-resistant macrophages.Engineering anthrax toxin variants that exclusively form octamers and their application to targeting tumorsTranscriptional analysis of the three Nlrp1 paralogs in mice.NLRP1 inflammasome activation induces pyroptosis of hematopoietic progenitor cells.Direct proteolytic cleavage of NLRP1B is necessary and sufficient for inflammasome activation by anthrax lethal factor.Inflammasomes.Molecular determinants for a cardiovascular collapse in anthraxAnthrax edema factor toxicity is strongly mediated by the N-end ruleB. anthracis associated cardiovascular dysfunction and shock: the potential contribution of both non-toxin and toxin componentsDesigning inhibitors of anthrax toxinSelective inhibitor of endosomal trafficking pathways exploited by multiple toxins and viruses.Inflammasome sensor NLRP1 controls rat macrophage susceptibility to Toxoplasma gondii.Anthrax lethal factor as an immune target in humans and transgenic mice and the impact of HLA polymorphism on CD4+ T cell immunityThe cyclopentenone prostaglandin 15d-PGJ2 inhibits the NLRP1 and NLRP3 inflammasomesRegulation of inflammasome activation.Raxibacumab augments hemodynamic support and improves outcomes during shock with B. anthracis edema toxin alone or together with lethal toxin in canines.Profiling lethal factor interacting proteins from human stomach using T7 phage display screening.
P2860
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P2860
Anthrax lethal factor cleavage of Nlrp1 is required for activation of the inflammasome
description
2012 nî lūn-bûn
@nan
2012 թուականին հրատարակուած գիտական յօդուած
@hyw
2012 թվականին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Anthrax lethal factor cleavage of Nlrp1 is required for activation of the inflammasome
@ast
Anthrax lethal factor cleavage of Nlrp1 is required for activation of the inflammasome
@en
Anthrax lethal factor cleavage of Nlrp1 is required for activation of the inflammasome
@nl
type
label
Anthrax lethal factor cleavage of Nlrp1 is required for activation of the inflammasome
@ast
Anthrax lethal factor cleavage of Nlrp1 is required for activation of the inflammasome
@en
Anthrax lethal factor cleavage of Nlrp1 is required for activation of the inflammasome
@nl
prefLabel
Anthrax lethal factor cleavage of Nlrp1 is required for activation of the inflammasome
@ast
Anthrax lethal factor cleavage of Nlrp1 is required for activation of the inflammasome
@en
Anthrax lethal factor cleavage of Nlrp1 is required for activation of the inflammasome
@nl
P2093
P2860
P50
P3181
P1433
P1476
Anthrax lethal factor cleavage of Nlrp1 is required for activation of the inflammasome
@en
P2093
Inka Sastalla
Jonathan L Levinsohn
Kristina A Hellmich
Matthew A Getz
Rasem Fattah
Zachary L Newman
P2860
P304
P3181
P356
10.1371/JOURNAL.PPAT.1002638
P407
P577
2012-01-01T00:00:00Z