Characterization of the interaction of full-length HIV-1 Vif protein with its key regulator CBFβ and CRL5 E3 ubiquitin ligase components
about
Structural insight into dGTP-dependent activation of tetrameric SAMHD1 deoxynucleoside triphosphate triphosphohydrolaseMultiple APOBEC3 restriction factors for HIV-1 and one Vif to rule them allSuppression of APOBEC3-mediated restriction of HIV-1 by VifThe Road Less Traveled: HIV's Use of Alternative Routes through Cellular PathwaysInsight into the HIV-1 Vif SOCS-box-ElonginBC interactionStructural analysis of viral infectivity factor of HIV type 1 and its interaction with A3G, EloC and EloBCytidine deaminase efficiency of the lentiviral viral restriction factor APOBEC3C correlates with dimerization.Identification of HIV-1 Vif regions required for CBF-β interaction and APOBEC3 suppressionCore-binding factor β increases the affinity between human Cullin 5 and HIV-1 Vif within an E3 ligase complexCore binding factor beta plays a critical role by facilitating the assembly of the Vif-cullin 5 E3 ubiquitin ligase.Evolutionarily conserved requirement for core binding factor beta in the assembly of the human immunodeficiency virus/simian immunodeficiency virus Vif-cullin 5-RING E3 ubiquitin ligase.Core-binding factor subunit beta is not required for non-primate lentiviral Vif-mediated APOBEC3 degradation.Insights into the dual activity of SIVmac239 Vif against human and African green monkey APOBEC3G.Requirement of HIV-1 Vif C-terminus for Vif-CBF-β interaction and assembly of CUL5-containing E3 ligaseEvolutionarily conserved pressure for the existence of distinct G2/M cell cycle arrest and A3H inactivation functions in HIV-1 VifInteractions between HIV-1 Vif and human ElonginB-ElonginC are important for CBF-β binding to Vif.HIV-1 Vif N-terminal motif is required for recruitment of Cul5 to suppress APOBEC3.Dispersed and conserved hydrophobic residues of HIV-1 Vif are essential for CBFβ recruitment and A3G suppression.Identification of a tripartite interaction between the N-terminus of HIV-1 Vif and CBFβ that is critical for Vif functionCBFβ enhances de novo protein biosynthesis of its binding partners HIV-1 Vif and RUNX1 and potentiates the Vif-induced degradation of APOBEC3G.Clues for two-step virion infectivity factor regulation by core binding factor beta.Conserved Interaction of Lentiviral Vif Molecules with HIV-1 Gag and Differential Effects of Species-Specific Vif on Virus Production.Determinants of efficient degradation of APOBEC3 restriction factors by HIV-1 Vif.Differential requirements for HIV-1 Vif-mediated APOBEC3G degradation and RUNX1-mediated transcription by core binding factor beta.Structural basis for hijacking CBF-β and CUL5 E3 ligase complex by HIV-1 Vif.HIV type 1 viral infectivity factor and the RUNX transcription factors interact with core binding factor β on genetically distinct surfaces.CBFβ stabilizes HIV Vif to counteract APOBEC3 at the expense of RUNX1 target gene expression.Moloney leukemia virus 10 (MOV10) inhibits the degradation of APOBEC3G through interference with the Vif-mediated ubiquitin-proteasome pathway.
P2860
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P2860
Characterization of the interaction of full-length HIV-1 Vif protein with its key regulator CBFβ and CRL5 E3 ubiquitin ligase components
description
2012 nî lūn-bûn
@nan
2012 թուականին հրատարակուած գիտական յօդուած
@hyw
2012 թվականին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Characterization of the intera ...... E3 ubiquitin ligase components
@ast
Characterization of the intera ...... E3 ubiquitin ligase components
@en
Characterization of the intera ...... E3 ubiquitin ligase components
@nl
type
label
Characterization of the intera ...... E3 ubiquitin ligase components
@ast
Characterization of the intera ...... E3 ubiquitin ligase components
@en
Characterization of the intera ...... E3 ubiquitin ligase components
@nl
prefLabel
Characterization of the intera ...... E3 ubiquitin ligase components
@ast
Characterization of the intera ...... E3 ubiquitin ligase components
@en
Characterization of the intera ...... E3 ubiquitin ligase components
@nl
P2093
P2860
P1433
P1476
Characterization of the intera ...... E3 ubiquitin ligase components
@en
P2093
Sean L Evans
Xiao-Fang Yu
P2860
P304
P356
10.1371/JOURNAL.PONE.0033495
P407
P577
2012-01-01T00:00:00Z