Lestaurtinib inhibits histone phosphorylation and androgen-dependent gene expression in prostate cancer cells
about
Tofacitinib and analogs as inhibitors of the histone kinase PRK1 (PKN1).Exploiting Epigenetic Alterations in Prostate Cancer.Crystal structures of PRK1 in complex with the clinical compounds lestaurtinib and tofacitinib reveal ligand induced conformational changes.Drug repurposing screen identifies lestaurtinib amplifies the ability of the poly (ADP-ribose) polymerase 1 inhibitor AG14361 to kill breast cancer associated gene-1 mutant and wild type breast cancer cells.Development and thermodynamic evaluation of novel lipid raft stationary phase chromatography for screening potential antitumor agents.Identification of Highly Potent Protein Kinase C-Related Kinase 1 Inhibitors by Virtual Screening, Binding Free Energy Rescoring, and in vitro Testing.Current trends in epigenetic drug discovery.The Multifaceted Roles of STAT3 Signaling in the Progression of Prostate Cancer.Protein kinase C-related kinase 1 and 2 play an essential role in thromboxane-mediated neoplastic responses in prostate cancer.PRK1/PKN1 controls migration and metastasis of androgen-independent prostate cancer cells.Signaling coupled epigenomic regulation of gene expression.Impaired lymphocyte trafficking in mice deficient in the kinase activity of PKN1.PKN2 is essential for mouse embryonic development and proliferation of mouse fibroblasts.Exome-wide analysis identifies three low-frequency missense variants associated with pancreatic cancer risk in Chinese populations
P2860
Q30313903-C34FE48F-F329-4BDD-96E4-B53345279AF2Q33755160-B2A20A50-556E-442E-A75A-1C25517E4DA6Q34028255-ACBD2702-2126-479D-9886-1F84CAE8903FQ34501206-F4BDC4F3-B02A-4A87-9951-99E9AFCAF35CQ35140616-D225755F-11C2-4F25-8CA4-5452EFD1549DQ36089876-34D87673-D4EF-4BDE-86B6-51D10C43CE06Q38060183-81AA156E-1B7A-405C-B053-3B3903479709Q38203779-E1B7871E-1B27-47E7-8ACE-A9FC8486A291Q38841874-F24D0D60-79AB-4FF7-AB8A-34C5D37ACA68Q38928703-A67E87D6-89E9-4ED8-8D35-0AE5BEFED5DEQ39398333-D61196AF-28E5-4A8B-B81C-9D77D74F58C1Q41331822-FD2BA79C-F150-4E7E-960A-6F6DDA298433Q48350071-25553B56-FD75-41C8-A871-064C30DE73B6Q58751735-7839625E-A4CE-4843-9D34-42468B1BAAB0
P2860
Lestaurtinib inhibits histone phosphorylation and androgen-dependent gene expression in prostate cancer cells
description
2012 nî lūn-bûn
@nan
2012 թուականին հրատարակուած գիտական յօդուած
@hyw
2012 թվականին հրատարակված գիտական հոդված
@hy
2012年の論文
@ja
2012年論文
@yue
2012年論文
@zh-hant
2012年論文
@zh-hk
2012年論文
@zh-mo
2012年論文
@zh-tw
2012年论文
@wuu
name
Lestaurtinib inhibits histone ...... ssion in prostate cancer cells
@ast
Lestaurtinib inhibits histone ...... ssion in prostate cancer cells
@en
Lestaurtinib inhibits histone ...... ssion in prostate cancer cells
@nl
type
label
Lestaurtinib inhibits histone ...... ssion in prostate cancer cells
@ast
Lestaurtinib inhibits histone ...... ssion in prostate cancer cells
@en
Lestaurtinib inhibits histone ...... ssion in prostate cancer cells
@nl
prefLabel
Lestaurtinib inhibits histone ...... ssion in prostate cancer cells
@ast
Lestaurtinib inhibits histone ...... ssion in prostate cancer cells
@en
Lestaurtinib inhibits histone ...... ssion in prostate cancer cells
@nl
P2093
P2860
P1433
P1476
Lestaurtinib inhibits histone ...... ssion in prostate cancer cells
@en
P2093
Adrien Eberlin
Eric Metzger
German Erlenkamp
Inna Slynko
Jens Köhler
Roland Schüle
Tobias Rumpf
P2860
P304
P356
10.1371/JOURNAL.PONE.0034973
P407
P577
2012-01-01T00:00:00Z