Cloning, expression, and characterization of Mycobacterium tuberculosis dihydrofolate reductase

Cloning, expression, and characterization of Mycobacterium tuberculosis dihydrofolate reductase

Item
http://www.wikidata.org/entity/Q28487175
The combination of sulfamethoxazole, trimethoprim, and isoniazid or rifampin is bactericidal and prevents the emergence of drug resistance in Mycobacterium tuberculosisStrategies for potentiation of ethionamide and folate antagonists against Mycobacterium tuberculosisMycobacterium tuberculosis folate metabolism and the mechanistic basis for para-aminosalicylic acid susceptibility and resistanceHigh-throughput screening and sensitized bacteria identify an M. tuberculosis dihydrofolate reductase inhibitor with whole cell activityTrypanosoma brucei DHFR-TS Revisited: Characterisation of a Bifunctional and Highly Unstable Recombinant Dihydrofolate Reductase-Thymidylate SynthaseNew small-molecule inhibitors of dihydrofolate reductase inhibit Streptococcus mutans.Design and Synthesis of a Focused Library of Diamino Triazines as Potential Mycobacterium tuberculosis DHFR InhibitorsThe identification of novel Mycobacterium tuberculosis DHFR inhibitors and the investigation of their binding preferences by using molecular modelling.Investigating essential gene function in Mycobacterium tuberculosis using an efficient CRISPR interference system.Recent advances in antituberculous drug development and novel drug targets.Rational drug design, synthesis and biological evaluation of dihydrofolate reductase inhibitors as antituberculosis agents.Development of new antituberculous agents based on new drug targets and structure-activity relationship.Programmable transcriptional repression in mycobacteria using an orthogonal CRISPR interference platform.A novel high-throughput B1H-ChIP method for efficiently validating and screening specific regulator-target promoter interactions.Binding mode analysis of 2,4-diamino-5-methyl-5-deaza-6-substituted pteridines with Mycobacterium tuberculosis and human dihydrofolate reductases.
P2860

Cloning, expression, and characterization of Mycobacterium tuberculosis dihydrofolate reductase

Item
http://www.wikidata.org/entity/Q28487175
description
2004 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի մարտին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2004
@ast
scientific journal article
@en
vedecký článok (publikovaný 2004/03/12)
@sk
vědecký článek publikovaný v roce 2004
@cs
wetenschappelijk artikel (gepubliceerd op 2004/03/12)
@nl
наукова стаття, опублікована в березні 2004
@uk
مقالة علمية (نشرت في 12-3-2004)
@ar
name
Cloning, expression, and chara ...... ulosis dihydrofolate reductase
@ast
Cloning, expression, and chara ...... ulosis dihydrofolate reductase
@en
Cloning, expression, and chara ...... ulosis dihydrofolate reductase
@nl
type
label
Cloning, expression, and chara ...... ulosis dihydrofolate reductase
@ast
Cloning, expression, and chara ...... ulosis dihydrofolate reductase
@en
Cloning, expression, and chara ...... ulosis dihydrofolate reductase
@nl
prefLabel
Cloning, expression, and chara ...... ulosis dihydrofolate reductase
@ast
Cloning, expression, and chara ...... ulosis dihydrofolate reductase
@en
Cloning, expression, and chara ...... ulosis dihydrofolate reductase
@nl
P1433
P1476
P2093
P304
P31
P3181
P356
P433
P478
P577
P5875
P698
P921
P3181
P356
P1433
P1476
Cloning, expression, and chara ...... ulosis dihydrofolate reductase
@en
P2093
P304
P31
P3181
P356
10.1016/S0378-1097(04)00038-2
P433
P478
P577
P5875
P698
P921