A novel mycothiol-dependent detoxification pathway in mycobacteria involving mycothiol S-conjugate amidase
about
The metabolism of nitrosothiols in the Mycobacteria: identification and characterization of S-nitrosomycothiol reductaseBiosynthesis and functions of bacillithiol, a major low-molecular-weight thiol in BacilliBiosynthesis and functions of mycothiol, the unique protective thiol of ActinobacteriaDissecting the essentiality of the bifunctional trypanothione synthetase-amidase in Trypanosoma brucei using chemical and genetic methodsBacillithiol: a key protective thiol in Staphylococcus aureusCrystal structure of the conserved protein TT1542 fromThermus thermophilusHB8The crystal structure of 1-D-myo-inosityl 2-acetamido-2-deoxy-alpha-D-glucopyranoside deacetylase (MshB) from Mycobacterium tuberculosis reveals a zinc hydrolase with a lactate dehydrogenase foldThe 1.6 Å Crystal Structure of Mycobacterium smegmatis MshC: The Penultimate Enzyme in the Mycothiol Biosynthetic Pathway †A new crystal form of MshB from Mycobacterium tuberculosis with glycerol and acetate in the active site suggests the catalytic mechanismGlutathione disulfide and S-nitrosoglutathione detoxification by Mycobacterium tuberculosis thioredoxin systemFunctional genomics reveals the sole sulphate transporter of the Mycobacterium tuberculosis complex and its relevance to the acquisition of sulphur in vivoFunctional demonstration of reverse transsulfuration in the Mycobacterium tuberculosis complex reveals that methionine is the preferred sulfur source for pathogenic MycobacteriaN-Acetyl-1-D-myo-inosityl-2-amino-2-deoxy-alpha-D-glucopyranoside deacetylase (MshB) is a key enzyme in mycothiol biosynthesisMycothiol biosynthesis is essential for ethionamide susceptibility in Mycobacterium tuberculosisBiochemistry of the initial steps of mycothiol biosynthesisMycothiol regulates and is regulated by a thiol-specific antisigma factor RsrA and sigma(R) in Streptomyces coelicolorFunctional characterization of Corynebacterium glutamicum mycothiol S-conjugate amidaseAn N-acyl homolog of mycothiol is produced in marine actinomycetesEvaluation of NTF1836 as an inhibitor of the mycothiol biosynthetic enzyme MshC in growing and non-replicating Mycobacterium tuberculosis.Mycothiol-deficient Mycobacterium smegmatis mutants are hypersensitive to alkylating agents, free radicals, and antibiotics.Steady-state and pre-steady-state kinetic analysis of Mycobacterium smegmatis cysteine ligase (MshC).Arsenate reductase, mycothiol, and mycoredoxin concert thiol/disulfide exchangeDrug targets in mycobacterial sulfur metabolism.New targets and inhibitors of mycobacterial sulfur metabolism.The DinB superfamily includes novel mycothiol, bacillithiol, and glutathione S-transferases.Thiols in nitric oxide synthase-containing Nocardia sp. strain NRRL 5646.Examination of bacterial resistance to exogenous nitric oxide.Mycothiol import by Mycobacterium smegmatis and function as a resource for metabolic precursors and energy productionOxidative activation of thiacetazone by the Mycobacterium tuberculosis flavin monooxygenase EtaA and human FMO1 and FMO3.Ergothioneine is a secreted antioxidant in Mycobacterium smegmatisOverexpression of Mycothiol Disulfide Reductase Enhances Corynebacterium glutamicum Robustness by Modulating Cellular Redox Homeostasis and Antioxidant Proteins under Oxidative Stress.Toward the catalytic mechanism of a cysteine ligase (MshC) from Mycobacterium smegmatis: an enzyme involved in the biosynthetic pathway of mycothiol.Structures and mechanisms of the mycothiol biosynthetic enzymes.Targeted mutagenesis of the Mycobacterium smegmatis mca gene, encoding a mycothiol-dependent detoxification protein.Detoxification of toxins by bacillithiol in Staphylococcus aureus.The interaction topology of Mycobacterium tuberculosis genes response to capreomycin and novel clues for more drug targets.Mycobacterium sulfur metabolism and implications for novel drug targets.Mycothiol: a target for potentiation of rifampin and other antibiotics against Mycobacterium tuberculosis.Protein kinase C inhibitors: a patent review (2008 - 2009).Structure and function of the LmbE-like superfamily.
P2860
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P2860
A novel mycothiol-dependent detoxification pathway in mycobacteria involving mycothiol S-conjugate amidase
description
2000 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2000
@ast
im September 2000 veröffentlicher wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2000/09/05)
@sk
vědecký článek publikovaný v roce 2000
@cs
wetenschappelijk artikel (gepubliceerd op 2000/09/05)
@nl
наукова стаття, опублікована у вересні 2000
@uk
مقالة علمية (نشرت في 5-9-2000)
@ar
name
A novel mycothiol-dependent de ...... mycothiol S-conjugate amidase
@ast
A novel mycothiol-dependent de ...... mycothiol S-conjugate amidase
@en
A novel mycothiol-dependent de ...... mycothiol S-conjugate amidase
@nl
type
label
A novel mycothiol-dependent de ...... mycothiol S-conjugate amidase
@ast
A novel mycothiol-dependent de ...... mycothiol S-conjugate amidase
@en
A novel mycothiol-dependent de ...... mycothiol S-conjugate amidase
@nl
prefLabel
A novel mycothiol-dependent de ...... mycothiol S-conjugate amidase
@ast
A novel mycothiol-dependent de ...... mycothiol S-conjugate amidase
@en
A novel mycothiol-dependent de ...... mycothiol S-conjugate amidase
@nl
P2093
P3181
P356
P1433
P1476
A novel mycothiol-dependent de ...... mycothiol S-conjugate amidase
@en
P2093
G. L. Newton
R. C. Fahey
P304
10739–10746
P3181
P356
10.1021/BI000356N
P407
P577
2000-09-05T00:00:00Z