A mycothiol synthase mutant of Mycobacterium tuberculosis has an altered thiol-disulfide content and limited tolerance to stress
about
Structural and enzymatic analysis of MshA from Corynebacterium glutamicum: substrate-assisted catalysisBiosynthesis and functions of mycothiol, the unique protective thiol of ActinobacteriaThe emerging role of gasotransmitters in the pathogenesis of tuberculosisRedox homeostasis in mycobacteria: the key to tuberculosis control?Crystal structures and site-directed mutagenesis of a mycothiol-dependent enzyme reveal a novel folding and molecular basis for mycothiol-mediated maleylpyruvate isomerizationThe Oxidation-sensing Regulator (MosR) Is a New Redox-dependent Transcription Factor in Mycobacterium tuberculosisMycoredoxin-1 is one of the missing links in the oxidative stress defence mechanism of MycobacteriaRedox regulation by reversible protein S-thiolation in bacteriaThe regulation of sulfur metabolism in Mycobacterium tuberculosisMycothiol biosynthesis is essential for ethionamide susceptibility in Mycobacterium tuberculosisBiochemistry of the initial steps of mycothiol biosynthesisThe multifunctional histone-like protein Lsr2 protects mycobacteria against reactive oxygen intermediatesMycobacterium tuberculosis Thioredoxin Reductase Is Essential for Thiol Redox Homeostasis but Plays a Minor Role in Antioxidant DefenseAn N-acyl homolog of mycothiol is produced in marine actinomycetesEvaluation of NTF1836 as an inhibitor of the mycothiol biosynthetic enzyme MshC in growing and non-replicating Mycobacterium tuberculosis.Drug targets in mycobacterial sulfur metabolism.New targets and inhibitors of mycobacterial sulfur metabolism.Mycobacterial survival strategies in the phagosome: defence against host stresses.The Mycobacterium tuberculosis CysQ phosphatase modulates the biosynthesis of sulfated glycolipids and bacterial growth.The DinB superfamily includes novel mycothiol, bacillithiol, and glutathione S-transferases.Mycothiol import by Mycobacterium smegmatis and function as a resource for metabolic precursors and energy productionNonsteroidal anti-inflammatory drug sensitizes Mycobacterium tuberculosis to endogenous and exogenous antimicrobialsStructures and mechanisms of the mycothiol biosynthetic enzymes.Chapter 2: Biogenesis of the cell wall and other glycoconjugates of Mycobacterium tuberculosis.Mycothiol: a target for potentiation of rifampin and other antibiotics against Mycobacterium tuberculosis.Mycobacterium tuberculosis WhiB3 Responds to Vacuolar pH-induced Changes in Mycothiol Redox Potential to Modulate Phagosomal Maturation and Virulence.OsmC proteins of Mycobacterium tuberculosis and Mycobacterium smegmatis protect against organic hydroperoxide stress.Development of new antituberculous agents based on new drug targets and structure-activity relationship.Comparative Proteomic Analysis of Mycobacterium tuberculosis Lineage 7 and Lineage 4 Strains Reveals Differentially Abundant Proteins Linked to Slow Growth and Virulence.Fumarase Deficiency Causes Protein and Metabolite Succination and Intoxicates Mycobacterium tuberculosis.Monitoring global protein thiol-oxidation and protein S-mycothiolation in Mycobacterium smegmatis under hypochlorite stress.Precise null deletion mutations of the mycothiol synthesis genes reveal their role in isoniazid and ethionamide resistance in Mycobacterium smegmatis.Organic hydroperoxide resistance protein and ergothioneine compensate for loss of mycothiol in Mycobacterium smegmatis mutants.The response of mycobacterium tuberculosis to reactive oxygen and nitrogen speciesTargeting Mycobacterium tuberculosis Sensitivity to Thiol Stress at Acidic pH Kills the Bacterium and Potentiates Antibiotics.Thiol Redox and pKa Properties of Mycothiol, the Predominant Low-Molecular-Weight Thiol Cofactor in the Actinomycetes.HpoR, a novel c-di-GMP effective transcription factor, links the second messenger's regulatory function to the mycobacterial antioxidant defense.PknE, a serine/threonine protein kinase from Mycobacterium tuberculosis has a role in adaptive responses.Host-pathogen redox dynamics modulate Mycobacterium tuberculosis pathogenesis.
P2860
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P2860
A mycothiol synthase mutant of Mycobacterium tuberculosis has an altered thiol-disulfide content and limited tolerance to stress
description
2006 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2006
@ast
im September 2006 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2006/09/01)
@sk
vědecký článek publikovaný v roce 2006
@cs
wetenschappelijk artikel (gepubliceerd op 2006/09/01)
@nl
наукова стаття, опублікована у вересні 2006
@uk
مقالة علمية (نشرت في سبتمبر 2006)
@ar
name
A mycothiol synthase mutant of ...... nd limited tolerance to stress
@ast
A mycothiol synthase mutant of ...... nd limited tolerance to stress
@en
A mycothiol synthase mutant of ...... nd limited tolerance to stress
@nl
type
label
A mycothiol synthase mutant of ...... nd limited tolerance to stress
@ast
A mycothiol synthase mutant of ...... nd limited tolerance to stress
@en
A mycothiol synthase mutant of ...... nd limited tolerance to stress
@nl
prefLabel
A mycothiol synthase mutant of ...... nd limited tolerance to stress
@ast
A mycothiol synthase mutant of ...... nd limited tolerance to stress
@en
A mycothiol synthase mutant of ...... nd limited tolerance to stress
@nl
P2093
P2860
P3181
P356
P1476
A mycothiol synthase mutant of ...... nd limited tolerance to stress
@en
P2093
Gerald L. Newton
Nancy A. Buchmeier
Robert C. Fahey
P2860
P304
P3181
P356
10.1128/JB.00393-06
P407
P577
2006-09-01T00:00:00Z