Discovery of novel nitrobenzothiazole inhibitors for Mycobacterium tuberculosis ATP phosphoribosyl transferase (HisG) through virtual screening
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Automated docking screens: a feasibility studyA mapping of drug space from the viewpoint of small molecule metabolismMycobacterium tuberculosis phosphoribosylpyrophosphate synthetase: biochemical features of a crucial enzyme for mycobacterial cell wall biosynthesisComparative genomics analysis of Mycobacterium ulcerans for the identification of putative essential genes and therapeutic candidatesEnhancing hit identification in Mycobacterium tuberculosis drug discovery using validated dual-event Bayesian modelsSoftware and resources for computational medicinal chemistryDocking Screens for Novel Ligands Conferring New Biology.Analysis and hit filtering of a very large library of compounds screened against Mycobacterium tuberculosis.Validating new tuberculosis computational models with public whole cell screening aerobic activity datasets.Computational databases, pathway and cheminformatics tools for tuberculosis drug discovery.Essential metabolites of Mycobacterium tuberculosis and their mimics5-Chloro-benzothia-zole-2-spiro-3'-indolin-2'-one.Synthesis, biological evaluation and 2D-QSAR study of halophenyl bis-hydrazones as antimicrobial and antitubercular agents.Mycobacterium tuberculosis and Clostridium difficille interactomes: demonstration of rapid development of computational system for bacterial interactome prediction.Click with a boronic acid handle: a neighboring group-assisted click reaction that allows ready secondary functionalization.Mechanism of feedback allosteric inhibition of ATP phosphoribosyltransferase.Review of knowledge for rational design and identification of anti-tubercular compounds.The eradication of leprosy: molecular modeling techniques for novel drug discovery.Recently disclosed chemical entities as potential candidates for management of tuberculosis.Uncoupling conformational states from activity in an allosteric enzyme.N-(4-Chloro-1,3-benzothia-zol-2-yl)-2-(3-methyl-phen-yl)acetamide monohydrate.Campylobacter jejuni adenosine triphosphate phosphoribosyltransferase is an active hexamer that is allosterically controlled by the twisting of a regulatory tail.Green synthesis and crystal structure of 3-(benzo-thia-zol-2-yl)thio-phene.Synthesis of N-(6-Arylbenzo[d]thiazole-2-acetamide Derivatives and Their Biological Activities: An Experimental and Computational Approach.A Novel Comparative Genomics Analysis for Common Drug and Vaccine Targets in Corynebacterium pseudotuberculosis and other CMN Group of Human PathogensSynthesis of carboxyimidamide-substituted benzo[c][1,2,5]oxadiazoles and their analogs, and evaluation of biological activity against Leishmania donovaniBiological Aspects of Emerging Benzothiazoles: A Short Review
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P2860
Discovery of novel nitrobenzothiazole inhibitors for Mycobacterium tuberculosis ATP phosphoribosyl transferase (HisG) through virtual screening
description
2008 թուականի Հոկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի հոտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2008
@ast
im Oktober 2008 veröffentlichter wissenschaftlicher Artikel
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scientific journal article
@en
vedecký článok (publikovaný 2008/10/09)
@sk
vědecký článek publikovaný v roce 2008
@cs
wetenschappelijk artikel (gepubliceerd op 2008/10/09)
@nl
наукова стаття, опублікована в жовтні 2008
@uk
مقالة علمية (نشرت في 9-10-2008)
@ar
name
Discovery of novel nitrobenzot ...... isG) through virtual screening
@ast
Discovery of novel nitrobenzot ...... isG) through virtual screening
@en
Discovery of novel nitrobenzot ...... isG) through virtual screening
@nl
type
label
Discovery of novel nitrobenzot ...... isG) through virtual screening
@ast
Discovery of novel nitrobenzot ...... isG) through virtual screening
@en
Discovery of novel nitrobenzot ...... isG) through virtual screening
@nl
prefLabel
Discovery of novel nitrobenzot ...... isG) through virtual screening
@ast
Discovery of novel nitrobenzot ...... isG) through virtual screening
@en
Discovery of novel nitrobenzot ...... isG) through virtual screening
@nl
P2093
P2860
P356
P1476
Discovery of novel nitrobenzot ...... isG) through virtual screening
@en
P2093
James C. Sacchettini
Thomas R. Ioerger
Yoonsang Cho
P2860
P304
P356
10.1021/JM800328V
P407
P577
2008-10-09T00:00:00Z