Consensus HIV-1 FSU-A integrase gene variants electroporated into mice induce polyfunctional antigen-specific CD4+ and CD8+ T cells
about
A multi-head intradermal electroporation device allows for tailored and increased dose DNA vaccine delivery to the skinInfluence of Drug Resistance Mutations on the Activity of HIV-1 Subtypes A and B Integrases: a Comparative Study.Fusion to Flaviviral Leader Peptide Targets HIV-1 Reverse Transcriptase for Secretion and Reduces Its Enzymatic Activity and Ability to Induce Oxidative Stress but Has No Major Effects on Its Immunogenic Performance in DNA-Immunized Mice.A multi-head intradermal electroporation device allows for tailored and increased dose DNA vaccine delivery to the skin.Codon optimization and improved delivery/immunization regimen enhance the immune response against wild-type and drug-resistant HIV-1 reverse transcriptase, preserving its Th2-polarity.DNA immunization site determines the level of gene expression and the magnitude, but not the type of the induced immune response.
P2860
Consensus HIV-1 FSU-A integrase gene variants electroporated into mice induce polyfunctional antigen-specific CD4+ and CD8+ T cells
description
2013 nî lūn-bûn
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2013 թուականին հրատարակուած գիտական յօդուած
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2013 թվականին հրատարակված գիտական հոդված
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2013年の論文
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2013年論文
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2013年論文
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2013年論文
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2013年論文
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2013年論文
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2013年论文
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Consensus HIV-1 FSU-A integras ...... specific CD4+ and CD8+ T cells
@ast
Consensus HIV-1 FSU-A integras ...... specific CD4+ and CD8+ T cells
@en
Consensus HIV-1 FSU-A integras ...... specific CD4+ and CD8+ T cells
@nl
type
label
Consensus HIV-1 FSU-A integras ...... specific CD4+ and CD8+ T cells
@ast
Consensus HIV-1 FSU-A integras ...... specific CD4+ and CD8+ T cells
@en
Consensus HIV-1 FSU-A integras ...... specific CD4+ and CD8+ T cells
@nl
prefLabel
Consensus HIV-1 FSU-A integras ...... specific CD4+ and CD8+ T cells
@ast
Consensus HIV-1 FSU-A integras ...... specific CD4+ and CD8+ T cells
@en
Consensus HIV-1 FSU-A integras ...... specific CD4+ and CD8+ T cells
@nl
P2093
P2860
P1433
P1476
Consensus HIV-1 FSU-A integras ...... specific CD4+ and CD8+ T cells
@en
P2093
Alecia Viklund
Elizaveta Starodubova
Eva Gelius
Igor M Belyakov
Julia Agapkina
Linda Kostic
Maria G Isaguliants
Marina Gottikh
Oleg Latyshev
Olga Krotova
P2860
P304
P356
10.1371/JOURNAL.PONE.0062720
P407
P577
2013-01-01T00:00:00Z