Deletion of dop in Mycobacterium smegmatis abolishes pupylation of protein substrates in vivo
about
Bacterial ProteasomesThe pup-proteasome system of Mycobacterium tuberculosisThe Pup-Proteasome System of MycobacteriaProkaryotic ubiquitin-like protein modificationStructures of Pup ligase PafA and depupylase Dop from the prokaryotic ubiquitin-like modification pathwayBacterial Proteasomes: Mechanistic and Functional InsightsMolecular analysis of the prokaryotic ubiquitin-like protein (Pup) conjugation pathway in Mycobacterium tuberculosis"Depupylation" of prokaryotic ubiquitin-like protein from mycobacterial proteasome substratesDop functions as a depupylase in the prokaryotic ubiquitin-like modification pathwayThe mycobacterial Mpa-proteasome unfolds and degrades pupylated substrates by engaging Pup's N-terminusThe Mycobacterium tuberculosis proteasome active site threonine is essential for persistence yet dispensable for replication and resistance to nitric oxide.Deubiquitinating enzymes as promising drug targets for infectious diseases.Survival of mycobacteria depends on proteasome-mediated amino acid recycling under nutrient limitationThe pupylation pathway and its role in mycobacteria.Mycobacterial ubiquitin-like protein ligase PafA follows a two-step reaction pathway with a phosphorylated pup intermediate.Fate of pup inside the Mycobacterium proteasome studied by in-cell NMR.Reconstitution of the Mycobacterium tuberculosis pupylation pathway in Escherichia coliProteasomes and protein conjugation across domains of life.Activity of the mycobacterial proteasomal ATPase Mpa is reversibly regulated by pupylation.The Mechanism of Mycobacterium smegmatis PafA Self-PupylationPosttranslational modification of cellular proteins by a ubiquitin-like protein in bacteria.Mycobacterium tuberculosis prokaryotic ubiquitin-like protein-deconjugating enzyme is an unusual aspartate amidase.Game of 'Somes: Protein Destruction for Mycobacterium tuberculosis Pathogenesis.Allosteric transitions direct protein tagging by PafA, the prokaryotic ubiquitin-like protein (Pup) ligase.The pupylation machinery is involved in iron homeostasis by targeting the iron storage protein ferritin.Prokaryotic proteasomes: nanocompartments of degradation.The natural history of ubiquitin and ubiquitin-related domains.Proteases in Mycobacterium tuberculosis pathogenesis: potential as drug targets.Pupylation-dependent and -independent proteasomal degradation in mycobacteria.The regulatory significance of tag recycling in the mycobacterial Pup-proteasome system.AAA+ Machines of Protein Destruction in Mycobacteria.Mycobacterium tuberculosis Proteasome Accessory Factor A (PafA) Can Transfer Prokaryotic Ubiquitin-Like Protein (Pup) between SubstratesProfiling the Proteome of Mycobacterium tuberculosis during Dormancy and Reactivation.Mycobacterium smegmatis PafBC is involved in regulation of DNA damage responseCIPPN: computational identification of protein pupylation sites by using neural network.Pup recycling regulates the proteasome.Identification of Serine 119 as an Effective Inhibitor Binding Site of M. tuberculosis Ubiquitin-like Protein Ligase PafA Using Purified Proteins and M. smegmatis.
P2860
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P2860
Deletion of dop in Mycobacterium smegmatis abolishes pupylation of protein substrates in vivo
description
2010 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2010
@ast
im Dezember 2009 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2010/02/01)
@sk
vědecký článek publikovaný v roce 2010
@cs
wetenschappelijk artikel (gepubliceerd op 2010/02/01)
@nl
наукова стаття, опублікована в лютому 2010
@uk
مقالة علمية (نشرت في فبراير 2010)
@ar
name
Deletion of dop in Mycobacteri ...... of protein substrates in vivo
@ast
Deletion of dop in Mycobacteri ...... of protein substrates in vivo
@en
Deletion of dop in Mycobacteri ...... of protein substrates in vivo
@nl
type
label
Deletion of dop in Mycobacteri ...... of protein substrates in vivo
@ast
Deletion of dop in Mycobacteri ...... of protein substrates in vivo
@en
Deletion of dop in Mycobacteri ...... of protein substrates in vivo
@nl
prefLabel
Deletion of dop in Mycobacteri ...... of protein substrates in vivo
@ast
Deletion of dop in Mycobacteri ...... of protein substrates in vivo
@en
Deletion of dop in Mycobacteri ...... of protein substrates in vivo
@nl
P2093
P2860
P50
P1476
Deletion of dop in Mycobacteri ...... of protein substrates in vivo
@en
P2093
Beat Amstutz
Frank Imkamp
Frank Striebel
Tobias Rosenberger
P2860
P304
P356
10.1111/J.1365-2958.2009.07013.X
P407
P577
2009-12-16T00:00:00Z