The cold and menthol receptor TRPM8 contains a functionally important double cysteine motif
about
Roles of TRPM8 Ion Channels in Cancer: Proliferation, Survival, and InvasionNear-membrane dynamics and capture of TRPM8 channels within transient confinement domainsCysteine-rich secretory protein 4 is an inhibitor of transient receptor potential M8 with a role in establishing sperm functionExpression of temperature-sensitive ion channel TRPM8 in sperm cells correlates with vertebrate evolutionN-glycosylation determines the abundance of the transient receptor potential channel TRPP2Extracellular hydrophobic regions in scavenger receptor BI play a key role in mediating HDL-cholesterol transport.SR-BI/CD36 chimeric receptors define extracellular subdomains of SR-BI critical for cholesterol transport.Importance of a conserved sequence motif in transmembrane segment S3 for the gating of human TRPM8 and TRPM2N-glycosylation determines ionic permeability and desensitization of the TRPV1 capsaicin receptor.Functional and Modeling Studies of the Transmembrane Region of the TRPM8 ChannelProtease-activated receptor 2 (PAR2) protein and transient receptor potential vanilloid 4 (TRPV4) protein coupling is required for sustained inflammatory signaling.ThermoTRP channels in nociceptors: taking a lead from capsaicin receptor TRPV1Complex N-glycosylation stabilizes surface expression of transient receptor potential melastatin 4b protein.Post-Translational Modifications of TRP Channels.Trafficking of ThermoTRP Channels.Role of the transient receptor potential vanilloid 5 (TRPV5) protein N terminus in channel activity, tetramerization, and trafficking.N-glycosylation of the transient receptor potential melastatin 8 channel is altered in pancreatic cancer cells.Genetic variants affecting human TRPA1 or TRPM8 structure can be classified in vitro as 'well expressed', 'poorly expressed' or 'salvageable'.Human TRPM8 and TRPA1 pain channels, including a gene variant with increased sensitivity to agonists (TRPA1 R797T), exhibit differential regulation by SRC-tyrosine kinase inhibitor.N-glycosylation of TRPM8 ion channels modulates temperature sensitivity of cold thermoreceptor neurons.Regulation of activity of transient receptor potential melastatin 8 (TRPM8) channel by its short isoforms.Human lung epithelial cells express a functional cold-sensing TRPM8 variant.Effects of N-Glycosylation of the human cation channel TRPA1 on agonist-sensitivity.Bidirectional modulation of thermal and chemical sensitivity of TRPM8 channels by the initial region of the N-terminal domain.Surface expression and channel function of TRPM8 are cooperatively controlled by transmembrane segments S3 and S4.Activation of Human Transient Receptor Potential Melastatin-8 (TRPM8) by Calcium-Rich Particulate Materials and Effects on Human Lung Cells.Ion channel drug potency assay with an artificial bilayer chip.
P2860
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P2860
The cold and menthol receptor TRPM8 contains a functionally important double cysteine motif
description
2006 թուականի Դեկտեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի դեկտեմբերին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 2006
@ast
im Dezember 2006 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2006/12/08)
@sk
vědecký článek publikovaný v roce 2006
@cs
wetenschappelijk artikel (gepubliceerd op 2006/12/08)
@nl
наукова стаття, опублікована в грудні 2006
@uk
name
The cold and menthol receptor ...... mportant double cysteine motif
@ast
The cold and menthol receptor ...... mportant double cysteine motif
@en
The cold and menthol receptor ...... mportant double cysteine motif
@nl
type
label
The cold and menthol receptor ...... mportant double cysteine motif
@ast
The cold and menthol receptor ...... mportant double cysteine motif
@en
The cold and menthol receptor ...... mportant double cysteine motif
@nl
prefLabel
The cold and menthol receptor ...... mportant double cysteine motif
@ast
The cold and menthol receptor ...... mportant double cysteine motif
@en
The cold and menthol receptor ...... mportant double cysteine motif
@nl
P2093
P2860
P3181
P356
P1476
The cold and menthol receptor ...... mportant double cysteine motif
@en
P2093
Elizabeth Guida
Ilaria Dragoni
Peter McIntyre
P2860
P304
37353–37360
P3181
P356
10.1074/JBC.M607227200
P407
P577
2006-12-08T00:00:00Z