Targeted deletion of a single Sca8 ataxia locus allele in mice causes abnormal gait, progressive loss of motor coordination, and Purkinje cell dendritic deficits
about
Identification of Dlk1, Ptpru and Klhl1 as novel Nurr1 target genes in meso-diencephalic dopamine neuronsKelch proteins: emerging roles in skeletal muscle development and diseases.Spinocerebellar ataxia type 8 larger triplet expansion alters histone modification and induces RNA foci.RNA gain-of-function in spinocerebellar ataxia type 8.COP9 limits dendritic branching via Cullin3-dependent degradation of the actin-crosslinking BTB-domain protein Kelch.Mice overexpressing corticotropin-releasing factor show brain atrophy and motor dysfunctions.Loss of beta-III spectrin leads to Purkinje cell dysfunction recapitulating the behavior and neuropathology of spinocerebellar ataxia type 5 in humans.Calcium current homeostasis and synaptic deficits in hippocampal neurons from Kelch-like 1 knockout mice.Internal ribosome entry segment activity of ATXN8 opposite strand RNA.Long non-coding RNAs: versatile master regulators of gene expression and crucial players in cancer.Elimination of the actin-binding domain in kelch-like 1 protein induces T-type calcium channel modulation only in the presence of action potential waveforms.Bidirectional transcription of trinucleotide repeats: roles for excision repair.Chicken Ovalbumin Upstream Promoter-Transcription Factor II (COUP-TFII) regulates growth and patterning of the postnatal mouse cerebellum.Genetically engineered mouse models of the trinucleotide-repeat spinocerebellar ataxias.T-type current modulation by the actin-binding protein Kelch-like 1.Phosphorylation of ATXN1 at Ser776 in the cerebellum.Non-Ataxic Phenotypes of SCA8 Mimicking Amyotrophic Lateral Sclerosis and Parkinson Disease.Climbing Fiber Development Is Impaired in Postnatal Car8 (wdl) Mice.Heterozygous Deletion of KLHL1/ATX8OS at the SCA8 Locus Is Unlikely Associated With Cerebellar Impairment in Humans.Process elongation of oligodendrocytes is promoted by the Kelch-related protein MRP2/KLHL1.
P2860
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P2860
Targeted deletion of a single Sca8 ataxia locus allele in mice causes abnormal gait, progressive loss of motor coordination, and Purkinje cell dendritic deficits
description
2006 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2006 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2006
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im September 2006 veröffentlichter wissenschaftlicher Artikel
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scientific journal article
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vedecký článok (publikovaný 2006/09/27)
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vědecký článek publikovaný v roce 2006
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wetenschappelijk artikel (gepubliceerd op 2006/09/27)
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наукова стаття, опублікована у вересні 2006
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مقالة علمية (نشرت في 27-9-2006)
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name
Targeted deletion of a single ...... rkinje cell dendritic deficits
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Targeted deletion of a single ...... rkinje cell dendritic deficits
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Targeted deletion of a single ...... rkinje cell dendritic deficits
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type
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Targeted deletion of a single ...... rkinje cell dendritic deficits
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Targeted deletion of a single ...... rkinje cell dendritic deficits
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Targeted deletion of a single ...... rkinje cell dendritic deficits
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prefLabel
Targeted deletion of a single ...... rkinje cell dendritic deficits
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Targeted deletion of a single ...... rkinje cell dendritic deficits
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Targeted deletion of a single ...... rkinje cell dendritic deficits
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P2093
P1476
Targeted deletion of a single ...... rkinje cell dendritic deficits
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P2093
H Brent Clark
Kellie A Benzow
Michael D Koob
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P356
10.1523/JNEUROSCI.2595-06.2006
P407
P50
P577
2006-09-27T00:00:00Z