H2-M mutant mice are defective in the peptide loading of class II molecules, antigen presentation, and T cell repertoire selection
about
Human leukocyte Antigen-DM polymorphisms in autoimmune diseasesTransport of Streptococcus pneumoniae capsular polysaccharide in MHC Class II tubulesAn MHC class II restriction bias in CD4 T cell responses toward I-A is altered to I-E in DM-deficient miceCrossreactive T Cells Spotlight the Germline Rules for αβ T Cell-Receptor Interactions with MHC MoleculesCrystal Structure of the HLA-DM–HLA-DR1 Complex Defines Mechanisms for Rapid Peptide SelectionAchieving stability through editing and chaperoning: regulation of MHC class II peptide binding and expressionAltered major histocompatibility complex class II peptide loading in H2-O-deficient miceInvariant chain-independent function of H-2M in the formation of endogenous peptide-major histocompatibility complex class II complexes in vivoH2-Mbeta 1 and H2-Mbeta 2 heterodimers equally promote clip removal in I-A(q) molecules from autoimmune-prone DBA/1 miceProteases involved in MHC class II antigen presentationThe impact of the non-classical MHC proteins HLA-DM and HLA-DO on loading of MHC class II moleculesCLIP-derived self peptides bound to MHC class II molecules of medullary thymic epithelial cells differ from those of cortical thymic epithelial cells in their diversity, length, and C-terminal processing.Upregulation of the CLIP self peptide on mature dendritic cells antagonizes T helper type 1 polarization.Toward development and production of human T cells in swine for potential use in adoptive T cell immunotherapy.Pathways of antigen processing.Intracellular transport and peptide loading of MHC class II molecules: regulation by chaperones and motors.Peptide exchange in MHC molecules.The role of H2-O and HLA-DO in major histocompatibility complex class II-restricted antigen processing and presentation.Paradoxical intrathymic positive selection in mice with only a covalently presented agonist peptideTwo distinct gamma interferon-inducible promoters of the major histocompatibility complex class II transactivator gene are differentially regulated by STAT1, interferon regulatory factor 1, and transforming growth factor betaHomeostatic T cell proliferation: how far can T cells be activated to self-ligands?Negative selection of thymocytes expressing the D10 TCRPositive selection of self-MHC-reactive T cells by individual peptide-MHC class II complexes.Spontaneous proliferation of H2M-/- CD4 T cells results in unusual acute hepatocellular necrosisHLA-DM targets the hydrogen bond between the histidine at position beta81 and peptide to dissociate HLA-DR-peptide complexes.Diversity in MHC class II antigen presentation.The nonconventional MHC class II molecule DM governs diabetes susceptibility in NOD miceEarly endosomal maturation of MHC class II molecules independently of cysteine proteases and H-2DM.Functional HLA-DM on the surface of B cells and immature dendritic cells.The melting pot of the MHC II peptidomeIgE-mediated enhancement of antibody responses: the beneficial function of IgE?The activation threshold of CD4+ T cells is defined by TCR/peptide-MHC class II interactions in the thymic medullaAntigen presentation by keratinocytes directs autoimmune skin disease.HLA-DO as the optimizer of epitope selection for MHC class II antigen presentation.On the issue of peptide recognition in T cell development.Altered positive selection due to corecognition of floppy peptide/MHC II conformers supports an integrative model of thymic selection.T cell receptor specificity for major histocompatibility complex proteins.Diversity of T cell repertoire shaped by a single peptide ligand is critically affected by its amino acid residue at a T cell receptor contact.Evaluating the Role of HLA-DM in MHC Class II-Peptide Association Reactions.A T cell receptor-specific blockade of positive selection.
P2860
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P248
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P2860
H2-M mutant mice are defective in the peptide loading of class II molecules, antigen presentation, and T cell repertoire selection
description
1996 թուականի Փետրուարին հրատարակուած գիտական յօդուած
@hyw
1996 թվականի փետրվարին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 1996
@ast
im Februar 1996 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1996/02/23)
@sk
vědecký článek publikovaný v roce 1996
@cs
wetenschappelijk artikel (gepubliceerd op 1996/02/23)
@nl
наукова стаття, опублікована в лютому 1996
@uk
научни чланак (објављен 1996/02/23)
@sr
name
H2-M mutant mice are defective ...... nd T cell repertoire selection
@ast
H2-M mutant mice are defective ...... nd T cell repertoire selection
@en
H2-M mutant mice are defective ...... nd T cell repertoire selection
@nl
type
label
H2-M mutant mice are defective ...... nd T cell repertoire selection
@ast
H2-M mutant mice are defective ...... nd T cell repertoire selection
@en
H2-M mutant mice are defective ...... nd T cell repertoire selection
@nl
prefLabel
H2-M mutant mice are defective ...... nd T cell repertoire selection
@ast
H2-M mutant mice are defective ...... nd T cell repertoire selection
@en
H2-M mutant mice are defective ...... nd T cell repertoire selection
@nl
P2093
P921
P3181
P1433
P1476
H2-M mutant mice are defective ...... nd T cell repertoire selection
@en
P2093
S K Mendiratta
W D Martin
P304
P3181
P356
10.1016/S0092-8674(00)81030-2
P407
P50
P577
1996-02-01T00:00:00Z