A small natural molecule promotes mitochondrial fusion through inhibition of the deubiquitinase USP30 - Wikidata - awgldk - TriplyDB

A small natural molecule promotes mitochondrial fusion through inhibition of the deubiquitinase USP30

A small natural molecule promotes mitochondrial fusion through inhibition of the deubiquitinase USP30

http://www.wikidata.org/entity/Q28504988

about

Autophagy-Related Deubiquitinating Enzymes Involved in Health and Disease Mitochondrial targets for pharmacological intervention in human disease Death-associated Protein 3 Regulates Mitochondrial-encoded Protein Synthesis and Mitochondrial Dynamics Invited review: Mechanisms of GTP hydrolysis and conformational transitions in the dynamin superfamily SAMM50 Affects Mitochondrial Morphology through the Association of Drp1 in Mammalian Cells Regulation of Mitoflash Biogenesis and Signaling by Mitochondrial Dynamics.Implications of mitochondrial dynamics on neurodegeneration and on hypothalamic dysfunction.Deubiquitinating enzymes regulate PARK2-mediated mitophagy.A novel fission-independent role of dynamin-related protein 1 in cardiac mitochondrial respiration.Novel targets for mitochondrial medicine.The emerging role of deubiquitinating enzymes in genomic integrity, diseases, and therapeutics Chlorpyrifos inhibits neural induction via Mfn1-mediated mitochondrial dysfunction in human induced pluripotent stem cells Ophthalmic manifestations of inherited neurodegenerative disorders.New roles for mitochondrial proteases in health, ageing and disease.Mitochondrial quality control pathways as determinants of metabolic health.Molecular insight and pharmacological approaches targeting mitochondrial dynamics in skeletal muscle during obesity.Mitofusins: ubiquitylation promotes fusion.Regulation of mitochondrial inner membrane fusion: divergent evolution with similar solutions?Age-related accumulation of phosphorylated mitofusin 2 protein in retinal ganglion cells correlates with glaucoma progression.Decision for cell fate: deubiquitinating enzymes in cell cycle checkpoint.Mitochondrial redox status as a target for cardiovascular disease.Chemical and semisynthetic approaches to study and target deubiquitinases.Tributyltin induces mitochondrial fission through NAD-IDH dependent mitofusin degradation in human embryonic carcinoma cells.The pharmacological regulation of cellular mitophagy.Mitochondrial dynamics in type 2 diabetes: Pathophysiological implications.Emerging role of DUBs in tumor metastasis and apoptosis: Therapeutic implication.Mitochondrial Membrane Dynamics and Inherited Optic Neuropathies.Mitofusin 1 and optic atrophy 1 shift metabolism to mitochondrial respiration during aging.Signalling mechanisms underlying doxorubicin and Nox2 NADPH oxidase-induced cardiomyopathy: involvement of mitofusin-2.Mitochondrial Fission in Human Diseases.Roles of mitochondrial dynamics modulators in cardiac ischaemia/reperfusion injury.Characterization of the deubiquitination activity and substrate specificity of the chicken ubiquitin-specific protease 1/USP associated factor 1 complex.Beyond Deubiquitylation: USP30-Mediated Regulation of Mitochondrial Homeostasis.Mechanism and regulation of the Lys6-selective deubiquitinase USP30.Regulation of mitochondrial bioenergetics by the non-canonical roles of mitochondrial dynamics proteins in the heart.Deubiquitylating enzymes and drug discovery: emerging opportunities.Mitochondrial Targeting in Neurodegeneration: A Heme Perspective Deubiquitinating Enzymes Related to Autophagy: New Therapeutic Opportunities?Human Dendritic Cell Subsets Undergo Distinct Metabolic Reprogramming for Immune Response

P2860

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P2860

A small natural molecule promotes mitochondrial fusion through inhibition of the deubiquitinase USP30

http://www.wikidata.org/entity/Q28504988

description

2014 թուականի Ապրիլին հրատարակուած գիտական յօդուած

@hyw

2014 թվականի ապրիլին հրատարակված գիտական հոդված

@hy

artículu científicu espublizáu en 2014

@ast

im April 2014 veröffentlichter wissenschaftlicher Artikel

@de

scientific journal article

@en

vedecký článok (publikovaný 2014/04/01)

@sk

vědecký článek publikovaný v roce 2014

@cs

wetenschappelijk artikel (gepubliceerd op 2014/04/01)

@nl

наукова стаття, опублікована у квітні 2014

@uk

مقالة علمية (نشرت في أبريل 2014)

@ar

name

A small natural molecule promo ...... on of the deubiquitinase USP30

@ast

A small natural molecule promo ...... on of the deubiquitinase USP30

@en

A small natural molecule promo ...... on of the deubiquitinase USP30

@nl

type

label

A small natural molecule promo ...... on of the deubiquitinase USP30

@ast

A small natural molecule promo ...... on of the deubiquitinase USP30

@en

A small natural molecule promo ...... on of the deubiquitinase USP30

@nl

prefLabel

A small natural molecule promo ...... on of the deubiquitinase USP30

@ast

A small natural molecule promo ...... on of the deubiquitinase USP30

@en

A small natural molecule promo ...... on of the deubiquitinase USP30

@nl

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P1476

A small natural molecule promo ...... on of the deubiquitinase USP30

@en

P2093

Chaojun Yan

http://www.w3.org/2001/XMLSchema#string

Chen Yan

http://www.w3.org/2001/XMLSchema#string

Haijing Jin

http://www.w3.org/2001/XMLSchema#string

Haiyang Liu

http://www.w3.org/2001/XMLSchema#string

Hao Wu

http://www.w3.org/2001/XMLSchema#string

Jinhua Liu

http://www.w3.org/2001/XMLSchema#string

Jun Wang

http://www.w3.org/2001/XMLSchema#string

Laixin Xia

http://www.w3.org/2001/XMLSchema#string

Lei Du

http://www.w3.org/2001/XMLSchema#string

Lei Liu

http://www.w3.org/2001/XMLSchema#string

P2860

OPA1, encoding a dynamin-related GTPase, is mutated in autosomal dominant optic atrophy linked to chromosome 3q28

Control of mitochondrial morphology by a human mitofusin

MiD49 and MiD51, new components of the mitochondrial fission machinery.

MARCH-V is a novel mitofusin 2- and Drp1-binding protein able to change mitochondrial morphology

Mitofusin 1 and mitofusin 2 are ubiquitinated in a PINK1/parkin-dependent manner upon induction of mitophagy

Quantitation of mitochondrial dynamics by photolabeling of individual organelles shows that mitochondrial fusion is blocked during the Bax activation phase of apoptosis

Mff is an essential factor for mitochondrial recruitment of Drp1 during mitochondrial fission in mammalian cells

Identification of a novel protein that regulates mitochondrial fusion by modulating mitofusin (Mfn) protein function

The mitochondrial E3 ubiquitin ligase MARCH5 is required for Drp1 dependent mitochondrial division

OPA1 requires mitofusin 1 to promote mitochondrial fusion

P2888

P304

482-496

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P31

scholarly article

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3550491

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P356

10.1038/CR.2014.20

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P433

4

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P478

24

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P577

2014-02-11T00:00:00Z

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260152525

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P698

24513856

http://www.w3.org/2001/XMLSchema#string

P921

Ubiquitin specific peptidase 30

P932

3975501

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