Screening for increased plasma urea levels in a large-scale ENU mouse mutagenesis project reveals kidney disease models
about
Genome-wide ENU mutagenesis in combination with high density SNP analysis and exome sequencing provides rapid identification of novel mouse models of developmental diseaseGeneration and Standardized, Systemic Phenotypic Analysis of Pou3f3L423P Mutant MiceAngiotensin II overcomes strain-dependent resistance of rapid CKD progression in a new remnant kidney mouse modelStandardized, systemic phenotypic analysis of Slc12a1I299F mutant mice.Multi-omics approaches to disease.Standardized, systemic phenotypic analysis of Umod(C93F) and Umod(A227T) mutant mice.Loss of function mutation of the Slc38a3 glutamine transporter reveals its critical role for amino acid metabolism in the liver, brain, and kidney.Missense Mutation of POU Domain Class 3 Transcription Factor 3 in Pou3f3L423P Mice Causes Reduced Nephron Number and Impaired Development of the Thick Ascending Limb of the Loop of Henle.A new Otogelin ENU mouse model for autosomal-recessive nonsyndromic moderate hearing impairmentDiabetes models by screen for hyperglycemia in phenotype-driven ENU mouse mutagenesis projects.N-ethyl-N-nitrosourea mutagenesis produced a small number of mice with altered plasma electrolyte levelsStandardized, systemic phenotypic analysis reveals kidney dysfunction as main alteration of Kctd1 I27N mutant mice.Mutation of the Na(+)-K(+)-2Cl(-) cotransporter NKCC2 in mice is associated with severe polyuria and a urea-selective concentrating defect without hyperreninemia.Novel missense mutation of uromodulin in mice causes renal dysfunction with alterations in urea handling, energy, and bone metabolism.Generation of N-ethyl-N-nitrosourea-induced mouse mutants with deviations in plasma enzyme activities as novel organ-specific disease models.Type of uromodulin mutation and allelic status influence onset and severity of uromodulin-associated kidney disease in mice.
P2860
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P2860
Screening for increased plasma urea levels in a large-scale ENU mouse mutagenesis project reveals kidney disease models
description
2007 թուականի Մայիսին հրատարակուած գիտական յօդուած
@hyw
2007 թվականի մայիսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2007
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im Mai 2007 veröffentlichter wissenschaftlicher Artikel
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scientific journal article
@en
vedecký článok (publikovaný 2007/05/01)
@sk
vědecký článek publikovaný v roce 2007
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wetenschappelijk artikel (gepubliceerd op 2007/05/01)
@nl
наукова стаття, опублікована в травні 2007
@uk
مقالة علمية (نشرت في مايو 2007)
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name
Screening for increased plasma ...... reveals kidney disease models
@ast
Screening for increased plasma ...... reveals kidney disease models
@en
Screening for increased plasma ...... reveals kidney disease models
@nl
type
label
Screening for increased plasma ...... reveals kidney disease models
@ast
Screening for increased plasma ...... reveals kidney disease models
@en
Screening for increased plasma ...... reveals kidney disease models
@nl
prefLabel
Screening for increased plasma ...... reveals kidney disease models
@ast
Screening for increased plasma ...... reveals kidney disease models
@en
Screening for increased plasma ...... reveals kidney disease models
@nl
P2093
P2860
P50
P921
P3181
P1476
Screening for increased plasma ...... reveals kidney disease models
@en
P2093
Christina Schessl
Martina Klempt
Matthias Klaften
P2860
P304
F1560–1567
P3181
P356
10.1152/AJPRENAL.00213.2006
P50
P577
2007-05-01T00:00:00Z