Functional consequences of reduction in NMDA receptor glycine affinity in mice carrying targeted point mutations in the glycine binding site

Functional consequences of reduction in NMDA receptor glycine affinity in mice carrying targeted point mutations in the glycine binding site

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http://www.wikidata.org/entity/Q28505199
The N-methyl-D-aspartate receptor modulator GLYX-13 enhances learning and memory, in young adult and learning impaired aging ratsGLYX-13, an NMDA receptor glycine site functional partial agonist enhances cognition and produces antidepressant effects without the psychotomimetic side effects of NMDA receptor antagonistsEvaluation of Pax6 mutant rat as a model for autism.The involvement of N-methyl-D-aspartate receptor (NMDAR) subunit NR1 in the pathophysiology of schizophrenia.Discordant behavioral effects of psychotomimetic drugs in mice with altered NMDA receptor functionENU-mutagenesis mice with a non-synonymous mutation in Grin1 exhibit abnormal anxiety-like behaviors, impaired fear memory, and decreased acoustic startle response.Modeling the positive symptoms of schizophrenia in genetically modified mice: pharmacology and methodology aspectsGenetic loss of D-amino acid oxidase activity reverses schizophrenia-like phenotypes in mice.Effects of individual segmental trisomies of human chromosome 21 syntenic regions on hippocampal long-term potentiation and cognitive behaviors in mice.The N-methyl D-aspartate receptor glycine site and D-serine metabolism: an evolutionary perspectiveNMDA Neurotransmission Dysfunction in Behavioral and Psychological Symptoms of Alzheimer's Disease.d-amino acid oxidase knockout (Dao(-/-) ) mice show enhanced short-term memory performance and heightened anxiety, but no sleep or circadian rhythm disruption.Glycine site of NMDA receptor serves as a spatiotemporal detector of synaptic activity patternsThe glutamatergic aspects of schizophrenia molecular pathophysiology: role of the postsynaptic density, and implications for treatmentD-cycloserine facilitates synaptic plasticity but impairs glutamatergic neurotransmission in rat hippocampal slices.Glycine transporter type 1 blockade changes NMDA receptor-mediated responses and LTP in hippocampal CA1 pyramidal cells by altering extracellular glycine levels.Repeated maternal glucocorticoid treatment affects activity and hippocampal NMDA receptor expression in juvenile guinea pigs.
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Functional consequences of reduction in NMDA receptor glycine affinity in mice carrying targeted point mutations in the glycine binding site

Item
http://www.wikidata.org/entity/Q28505199
description
2000 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
2000 թվականի հունիսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2000
@ast
im Juni 2000 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2000/06/01)
@sk
vědecký článek publikovaný v roce 2000
@cs
wetenschappelijk artikel (gepubliceerd op 2000/06/01)
@nl
наукова стаття, опублікована в червні 2000
@uk
مقالة علمية (نشرت في يونيو 2000)
@ar
name
Functional consequences of red ...... ns in the glycine binding site
@ast
Functional consequences of red ...... ns in the glycine binding site
@en
Functional consequences of red ...... ns in the glycine binding site
@nl
type
label
Functional consequences of red ...... ns in the glycine binding site
@ast
Functional consequences of red ...... ns in the glycine binding site
@en
Functional consequences of red ...... ns in the glycine binding site
@nl
prefLabel
Functional consequences of red ...... ns in the glycine binding site
@ast
Functional consequences of red ...... ns in the glycine binding site
@en
Functional consequences of red ...... ns in the glycine binding site
@nl
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Functional consequences of red ...... ns in the glycine binding site
@en
P2093
P304
P31
P356
10.1523/JNEUROSCI.20-11-04037.2000
P407
P433
P478
P577
P698
P921
P932