Tissue-specific splicing of an Ndufs6 gene-trap insertion generates a mitochondrial complex I deficiency-specific cardiomyopathy
about
Heart failure and mitochondrial dysfunction: the role of mitochondrial fission/fusion abnormalities and new therapeutic strategiesMTO1-deficient mouse model mirrors the human phenotype showing complex I defect and cardiomyopathy.Complex I deficiency due to selective loss of Ndufs4 in the mouse heart results in severe hypertrophic cardiomyopathyPartial complex I deficiency due to the CNS conditional ablation of Ndufa5 results in a mild chronic encephalopathy but no increase in oxidative damage.Discovery of a strongly-interrelated gene network in corals under constant darkness by correlation analysis after wavelet transform on complex network modelMitochondrial Diseases Part I: mouse models of OXPHOS deficiencies caused by defects in respiratory complex subunits or assembly factors.Accessory NUMM (NDUFS6) subunit harbors a Zn-binding site and is essential for biogenesis of mitochondrial complex I.Cell-permeable protein therapy for complex I dysfunctionDevelopment of pharmacological strategies for mitochondrial disorders.No evidence of a role for mitochondrial complex I in Helicobacter pylori pathogenesis.Increased COUP-TFII expression in adult hearts induces mitochondrial dysfunction resulting in heart failure.Iron-regulatory proteins secure iron availability in cardiomyocytes to prevent heart failure.Mitochondrial Cardiomyopathy Caused by Elevated Reactive Oxygen Species and Impaired Cardiomyocyte Proliferation.
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P2860
Tissue-specific splicing of an Ndufs6 gene-trap insertion generates a mitochondrial complex I deficiency-specific cardiomyopathy
description
2012 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
article publié dans les Procee ...... f the United States of America
@fr
artículu científicu espublizáu en 2012
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im April 2012 veröffentlichter wissenschaftlicher Artikel
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scientific journal article
@en
vedecký článok (publikovaný 2012/04/17)
@sk
vědecký článek publikovaný v roce 2012
@cs
wetenschappelijk artikel (gepubliceerd op 2012/04/17)
@nl
наукова стаття, опублікована у квітні 2012
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name
Tissue-specific splicing of an ...... ciency-specific cardiomyopathy
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Tissue-specific splicing of an ...... ciency-specific cardiomyopathy
@en
Tissue-specific splicing of an ...... ciency-specific cardiomyopathy
@nl
type
label
Tissue-specific splicing of an ...... ciency-specific cardiomyopathy
@ast
Tissue-specific splicing of an ...... ciency-specific cardiomyopathy
@en
Tissue-specific splicing of an ...... ciency-specific cardiomyopathy
@nl
prefLabel
Tissue-specific splicing of an ...... ciency-specific cardiomyopathy
@ast
Tissue-specific splicing of an ...... ciency-specific cardiomyopathy
@en
Tissue-specific splicing of an ...... ciency-specific cardiomyopathy
@nl
P2093
P2860
P50
P921
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P1476
Tissue-specific splicing of an ...... ciency-specific cardiomyopathy
@en
P2093
Adrienne Laskowski
Belinda M Hardman
David R Grubb
Felicity A Rodda
James J Pitt
Jane Koleff
Jasper C Komen
Joseph J Smolich
Michael M H Cheung
P2860
P304
P356
10.1073/PNAS.1113987109
P407
P577
2012-04-02T00:00:00Z