THM1 negatively modulates mouse sonic hedgehog signal transduction and affects retrograde intraflagellar transport in cilia
about
A novel protein LZTFL1 regulates ciliary trafficking of the BBSome and SmoothenedBardet-Biedl syndrome 3 (Bbs3) knockout mouse model reveals common BBS-associated phenotypes and Bbs3 unique phenotypesBBS proteins interact genetically with the IFT pathway to influence SHH-related phenotypesTULP3 bridges the IFT-A complex and membrane phosphoinositides to promote trafficking of G protein-coupled receptors into primary ciliaC2orf62 and TTC17 are involved in actin organization and ciliogenesis in zebrafish and humanNovel Jbts17 mutant mouse model of Joubert syndrome with cilia transition zone defects and cerebellar and other ciliopathy related anomaliesSubunit interactions and organization of the Chlamydomonas reinhardtii intraflagellar transport complex A proteinsDisruption of Mks1 localization to the mother centriole causes cilia defects and developmental malformations in Meckel-Gruber syndromeCiliary abnormalities due to defects in the retrograde transport protein DYNC2H1 in short-rib polydactyly syndromeA polycystin-centric view of cyst formation and disease: the polycystins revisitedCilia functions in developmentCilia/Ift protein and motor -related bone diseases and mouse modelsPrimary cilium and sonic hedgehog signaling during neural tube patterning: role of GPCRs and second messengersThe nephronophthisis-related gene ift-139 is required for ciliogenesis in Caenorhabditis elegansSingle-molecule imaging of Hedgehog pathway protein Smoothened in primary cilia reveals binding events regulated by Patched1Mouse models of ciliopathies: the state of the art.Retrograde intraflagellar transport mutants identify complex A proteins with multiple genetic interactions in Chlamydomonas reinhardtii.A septin diffusion barrier at the base of the primary cilium maintains ciliary membrane protein distribution.Architecture and function of IFT complex proteins in ciliogenesisThe BBSome controls IFT assembly and turnaround in cilia.Trafficking in and to the primary cilium.Prostaglandin signalling regulates ciliogenesis by modulating intraflagellar transportDisruption of a ciliary B9 protein complex causes Meckel syndromeCranioectodermal Dysplasia, Sensenbrenner syndrome, is a ciliopathy caused by mutations in the IFT122 geneMotile cilia harbor serum response factor as a mechanism of environment sensing and injury response in the airwayIntraflagellar transport protein 122 antagonizes Sonic Hedgehog signaling and controls ciliary localization of pathway componentsTtc21b is required to restrict sonic hedgehog activity in the developing mouse forebrainThe IFT-A complex regulates Shh signaling through cilia structure and membrane protein traffickingMouse hitchhiker mutants have spina bifida, dorso-ventral patterning defects and polydactyly: identification of Tulp3 as a novel negative regulator of the Sonic hedgehog pathwayATMIN is a transcriptional regulator of both lung morphogenesis and ciliogenesis.Functional characterization of putative cilia genes by high-content analysisBroad-minded links cell cycle-related kinase to cilia assembly and hedgehog signal transductionTemporal deletion of Arl13b reveals that a mispatterned neural tube corrects cell fate over timeIFT25 links the signal-dependent movement of Hedgehog components to intraflagellar transportComplex interactions between genes controlling trafficking in primary ciliaTubby-like protein 3 (TULP3) regulates patterning in the mouse embryo through inhibition of Hedgehog signalingTTC26/DYF13 is an intraflagellar transport protein required for transport of motility-related proteins into flagellaMutations in mouse Ift144 model the craniofacial, limb and rib defects in skeletal ciliopathiesArl13b regulates ciliogenesis and the dynamic localization of Shh signaling proteinsDefective ciliogenesis, embryonic lethality and severe impairment of the Sonic Hedgehog pathway caused by inactivation of the mouse complex A intraflagellar transport gene Ift122/Wdr10, partially overlapping with the DNA repair gene Med1/Mbd4
P2860
Q24296671-DD9C03A4-E005-46DB-A758-5738605DCA32Q24298940-F5E4A253-A347-4E64-9B57-9921CAEC4D16Q24301377-56E9B0B6-15A7-4917-8A70-934041C7F836Q24301542-708AF726-10E2-4E6B-9C92-50431997D523Q24324242-BBFF26EA-8F27-4040-B392-1F9D099FFE58Q24336897-F259FBB0-13B2-4761-8A49-6267AE1ED04DQ24602508-A2ACCFC2-F636-439A-A1B8-F0D47E21FD17Q24622660-B70E339F-E561-4435-8492-919A26EB1507Q24644490-5AB18FA1-60F6-4734-8A80-D97FE26CB9B3Q26800974-0C8A8571-7342-45C9-8853-7CFD0B59C24FQ26829929-60761104-C8EE-4E8C-8817-F9EA282A50F0Q26865112-0CD20EDC-538E-4533-9799-A7BE42C5532EQ27011207-730A8A88-3AC7-4599-A622-7E557CB7D9BAQ27317381-D4ED49E6-7F8C-4FB3-BA6D-FB69892BD2FEQ27321140-8AD1AEA3-BAD2-4471-8BA9-D6C43DFFA1A7Q27692039-BB7C8FD9-6D45-4661-B33F-C94B3BABC1CEQ27967661-F69A561F-27E3-40BB-9239-5F69AA6F8968Q28000024-3D299238-369E-4373-9F6A-8927F511CC67Q28000079-62B7D39D-0E00-4675-9087-91B671DC46C8Q28000109-8DEEF45A-83C7-4B4A-BA8E-7775D94875FCQ28000124-BBD2916D-2C37-45EE-BDDA-225E5201F4A3Q28114834-950431E4-AC1E-4733-9EDE-596BE2AB5BE6Q28114969-2F7D7227-0B3D-4F2F-9666-C3C75C9863E9Q28283137-12E12055-5DEF-417B-AE31-82DC289F4FAFQ28391389-6795343E-7F90-4B7D-9C69-BDE13CE3D7D8Q28505068-3FC7E125-4A3B-45D6-8293-703C5ED5FF92Q28505900-AFE4CDB2-2EDE-4598-8463-1A0D56849F58Q28506316-02BDD108-B28B-47B6-BB12-144E73831D51Q28507114-F70374DB-E2C8-49D5-B024-070AEDDFFA03Q28507428-5F305EF3-00DE-4716-9481-6389095DBAE4Q28507517-9DE21C98-2B19-46B6-80DC-45383F7B4EDCQ28508448-9CE79540-C416-4D52-B1A3-BEB78C9EDAA3Q28511068-82FBE594-1133-471D-9A68-797E941CF4F5Q28511590-20683EB8-8A27-4CFE-A41D-C4D9CF9E4A29Q28512423-2266564A-9125-454B-AA08-0EB7E396B2D1Q28512967-A7FDBCA9-3783-4CA4-8709-EB9C693E9A38Q28585342-814B3111-A2B6-4B4F-B49A-3E11BCCBDC11Q28585520-7CE10861-6E43-4AE9-85C1-63E326A549DDQ28586066-8DB5CF06-617D-46A5-AD92-D2C06932D602Q28586893-65F0073A-4B74-4EFB-92DF-1E5D1F703522
P2860
THM1 negatively modulates mouse sonic hedgehog signal transduction and affects retrograde intraflagellar transport in cilia
description
2008 թուականի Ապրիլին հրատարակուած գիտական յօդուած
@hyw
2008 թվականի ապրիլին հրատարակված գիտական հոդված
@hy
articolo scientifico
@it
artículu científicu espublizáu en 2008
@ast
im April 2008 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2008/04/01)
@sk
vědecký článek publikovaný v roce 2008
@cs
wetenschappelijk artikel (gepubliceerd op 2008/04/01)
@nl
наукова стаття, опублікована у квітні 2008
@uk
name
THM1 negatively modulates mous ...... raflagellar transport in cilia
@ast
THM1 negatively modulates mous ...... raflagellar transport in cilia
@en
THM1 negatively modulates mous ...... raflagellar transport in cilia
@nl
type
label
THM1 negatively modulates mous ...... raflagellar transport in cilia
@ast
THM1 negatively modulates mous ...... raflagellar transport in cilia
@en
THM1 negatively modulates mous ...... raflagellar transport in cilia
@nl
prefLabel
THM1 negatively modulates mous ...... raflagellar transport in cilia
@ast
THM1 negatively modulates mous ...... raflagellar transport in cilia
@en
THM1 negatively modulates mous ...... raflagellar transport in cilia
@nl
P2093
P2860
P3181
P356
P1433
P1476
THM1 negatively modulates mous ...... raflagellar transport in cilia
@en
P2093
Allyson L. Chesebro
Annick Turbe-Doan
Bradley K. Yoder
Bruce J. Herron
Courtney J. Haycraft
David R. Beier
Haiyan Qiu
Jagesh V. Shah
Pamela V. Tran
Paul J. Scherz
P2860
P2888
P304
P3181
P356
10.1038/NG.105
P407
P577
2008-04-01T00:00:00Z
P5875
P6179
1007746003