Essential function for SAP family adaptors in the surveillance of hematopoietic cells by natural killer cells
about
Germinal center T follicular helper cell IL-4 production is dependent on signaling lymphocytic activation molecule receptor (CD150)Newtonian cell interactions shape natural killer cell educationA polymorphism in a phosphotyrosine signalling motif of CD229 (Ly9, SLAMF3) alters SH2 domain binding and T-cell activationCD84 negatively regulates IgE high-affinity receptor signaling in human mast cellsFine specificity and molecular competition in SLAM family receptor signallingCutting edge: The adapters EAT-2A and -2B are positive regulators of CD244- and CD84-dependent NK cell functions in the C57BL/6 mouseAnalysis of the cellular mechanism underlying inhibition of EAE after treatment with anti-NKG2A F(ab')2SLAM-family receptors: immune regulators with or without SAP-family adaptors.Manipulation of EAT-2 expression promotes induction of multiple beneficial regulatory and effector functions of the human innate immune system as a novel immunomodulatory strategyInnate lymphoid cells facilitate NK cell development through a lymphotoxin-mediated stromal microenvironmentDual function of the NK cell receptor 2B4 (CD244) in the regulation of HCV-specific CD8+ T cells.Adaptations of Natural Killer Cells to Self-MHC Class I.Interleukin-22 (IL-22) production by pulmonary Natural Killer cells and the potential role of IL-22 during primary influenza virus infectionMolecular pathogenesis of EBV susceptibility in XLP as revealed by analysis of female carriers with heterozygous expression of SAP.Natural killer cell mediated missing-self recognition can protect mice from primary chronic myeloid leukemia in vivo.Recognition of tumors by the innate immune system and natural killer cells.Towards mimicking short linear peptide motifs: identification of new mixed α,β-peptidomimetic ligands for SLAM-Associated Protein (SAP) by confocal on-bead screening.Elotuzumab enhances natural killer cell activation and myeloma cell killing through interleukin-2 and TNF-α pathwaysPDK1 orchestrates early NK cell development through induction of E4BP4 expression and maintenance of IL-15 responsivenessIdentification of SLAMF3 (CD229) as an inhibitor of hepatocellular carcinoma cell proliferation and tumour progression.Negative Regulation of Humoral Immunity Due to Interplay between the SLAMF1, SLAMF5, and SLAMF6 Receptors.Activation by SLAM Family Receptors Contributes to NK Cell Mediated "Missing-Self" Recognition.Microenvironment abnormalities and lymphomagenesis: Immunological aspects.Mouse natural killer cell development and maturation are differentially regulated by SHIP-1.Stepwise phosphorylation of p65 promotes NF-κB activation and NK cell responses during target cell recognition.NK cell development requires Tsc1-dependent negative regulation of IL-15-triggered mTORC1 activationThe adaptor molecule signaling lymphocytic activation molecule (SLAM)-associated protein (SAP) is essential in mechanisms involving the Fyn tyrosine kinase for induction and progression of collagen-induced arthritis.Deletion of Slam locus in mice reveals inhibitory role of SLAM family in NK cell responses regulated by cytokines and LFA-1.Controlling natural killer cell responses: integration of signals for activation and inhibition.Effects of KIR ligand incompatibility on clinical outcomes of umbilical cord blood transplantation without ATG for acute leukemia in complete remission.EAT-2, a SAP-like adaptor, controls NK cell activation through phospholipase Cγ, Ca++, and Erk, leading to granule polarization.Natural killer cell education and tolerance.Targeting natural killer cells and natural killer T cells in cancer.Cancer immunotherapy: accomplishments to date and future promise.NK cell self tolerance, responsiveness and missing self recognition.A hematopoietic cell-driven mechanism involving SLAMF6 receptor, SAP adaptors and SHP-1 phosphatase regulates NK cell education.DNAM-1 controls NK cell activation via an ITT-like motif.Differential Role of Hematopoietic and Nonhematopoietic Cell Types in the Regulation of NK Cell Tolerance and Responsiveness.SLAMF7 is critical for phagocytosis of haematopoietic tumour cells via Mac-1 integrin.Inhibitory 2B4 contributes to NK cell education and immunological derangements in XLP1 patients.
P2860
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P2860
Essential function for SAP family adaptors in the surveillance of hematopoietic cells by natural killer cells
description
2009 թուականի Սեպտեմբերին հրատարակուած գիտական յօդուած
@hyw
2009 թվականի սեպտեմբերին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2009
@ast
im September 2009 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2009/09/01)
@sk
vědecký článek publikovaný v roce 2009
@cs
wetenschappelijk artikel (gepubliceerd op 2009/09/01)
@nl
наукова стаття, опублікована у вересні 2009
@uk
مقالة علمية (نشرت في سبتمبر 2009)
@ar
name
Essential function for SAP fam ...... cells by natural killer cells
@ast
Essential function for SAP fam ...... cells by natural killer cells
@en
Essential function for SAP fam ...... cells by natural killer cells
@nl
type
label
Essential function for SAP fam ...... cells by natural killer cells
@ast
Essential function for SAP fam ...... cells by natural killer cells
@en
Essential function for SAP fam ...... cells by natural killer cells
@nl
prefLabel
Essential function for SAP fam ...... cells by natural killer cells
@ast
Essential function for SAP fam ...... cells by natural killer cells
@en
Essential function for SAP fam ...... cells by natural killer cells
@nl
P2093
P2860
P921
P3181
P356
P1433
P1476
Essential function for SAP fam ...... cells by natural killer cells
@en
P2093
André Veillette
Mario-Ernesto Cruz-Munoz
Ming-Chao Zhong
Riyan Chen
Zhongjun Dong
P2860
P304
P3181
P356
10.1038/NI.1763
P407
P577
2009-09-01T00:00:00Z