GLP-1 mediates antiapoptotic effect by phosphorylating Bad through a beta-arrestin 1-mediated ERK1/2 activation in pancreatic beta-cells
about
Regulation of glucose homeostasis by GLP-1Glucagon-like peptide-1 and cholecystokinin production and signaling in the pancreatic islet as an adaptive response to obesityMultifaceted role of β-arrestins in inflammation and diseaseHuman β-cell proliferation and intracellular signaling: part 3Regulation of G protein-coupled receptors by allosteric ligandsSystems-Level G Protein-Coupled Receptor Therapy Across a Neurodegenerative Continuum by the GLP-1 Receptor SystemPhysiology of proglucagon peptides: role of glucagon and GLP-1 in health and diseaseGlucagon-Like Peptide-1 and Its Class B G Protein-Coupled Receptors: A Long March to Therapeutic SuccessesConstruction of phosphorylation interaction networks by text mining of full-length articles using the eFIP system.Evidence that Ca2+ within the microdomain of the L-type voltage gated Ca2+ channel activates ERK in MIN6 cells in response to glucagon-like peptide-1.DPP4 deficiency exerts protective effect against H2O2 induced oxidative stress in isolated cardiomyocytes.Dipeptidyl peptidase IV inhibitor attenuates kidney injury in rat remnant kidney.Differential protective effects of exenatide, an agonist of GLP-1 receptor and Piragliatin, a glucokinase activator in beta cell response to streptozotocin-induced and endoplasmic reticulum stressesBeta-arrestin-1 protein represses adipogenesis and inflammatory responses through its interaction with peroxisome proliferator-activated receptor-gamma (PPARgamma)Anti-incretin, Anti-proliferative Action of Dopamine on β-CellsDefects in mitophagy promote redox-driven metabolic syndrome in the absence of TP53INP1Different downstream signalling of CCK1 receptors regulates distinct functions of CCK in pancreatic beta cellsSecond extracellular loop of human glucagon-like peptide-1 receptor (GLP-1R) has a critical role in GLP-1 peptide binding and receptor activationCharacterization of Zinc Influx Transporters (ZIPs) in Pancreatic β Cells: ROLES IN REGULATING CYTOSOLIC ZINC HOMEOSTASIS AND INSULIN SECRETION.Polymorphism and ligand dependent changes in human glucagon-like peptide-1 receptor (GLP-1R) function: allosteric rescue of loss of function mutation.Induction of miR-132 and miR-212 Expression by Glucagon-Like Peptide 1 (GLP-1) in Rodent and Human Pancreatic β-Cells.Effects of E2HSA, a Long-Acting Glucagon Like Peptide-1 Receptor Agonist, on Glycemic Control and Beta Cell Function in Spontaneous Diabetic db/db MiceEffect of Glucagon-like Peptide-1 on the Differentiation of Adipose-derived Stem Cells into Osteoblasts and AdipocytesNon-Hematopoietic β-Arrestin1 Confers Protection Against Experimental Colitis.Cocaine- and amphetamine-regulated transcript (CART) protects beta cells against glucotoxicity and increases cell proliferation.G Protein-coupled Receptor Biased Agonism.Inhibition of the MAP3 kinase Tpl2 protects rodent and human β-cells from apoptosis and dysfunction induced by cytokines and enhances anti-inflammatory actions of exendin-4.Therapeutic potential of β-arrestin- and G protein-biased agonists.Acting on Hormone Receptors with Minimal Side Effect on Cell Proliferation: A Timely Challenge Illustrated with GLP-1R and GPERMinireview: Dopaminergic regulation of insulin secretion from the pancreatic islet.Minireview: Signal bias, allosterism, and polymorphic variation at the GLP-1R: implications for drug discoveryRetinal pigment epithelial cells express a functional receptor for glucagon-like peptide-1 (GLP-1).Exendin-4 induces extracellular-superoxide dismutase through histone H3 acetylation in human retinal endothelial cells.Molecular mechanisms underlying physiological and receptor pleiotropic effects mediated by GLP-1R activation.Sitagliptin prevents inflammation and apoptotic cell death in the kidney of type 2 diabetic animalsSystematic Design of Trypsin Cleavage Site Mutated Exendin4-Cysteine 1, an Orally Bioavailable Glucagon-Like Peptide-1 Receptor Agonist.β-Arrestins: multifunctional signaling adaptors in type 2 diabetes.G protein-dependent and G protein-independent signaling pathways and their impact on cardiac function.Cardiovascular effects of incretin-based therapies.Physiology and emerging biochemistry of the glucagon-like peptide-1 receptor.
P2860
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P248
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P2860
GLP-1 mediates antiapoptotic effect by phosphorylating Bad through a beta-arrestin 1-mediated ERK1/2 activation in pancreatic beta-cells
description
2010 թուականի Յունուարին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի հունվարին հրատարակված գիտական հոդված
@hy
article publié dans la revue scientifique Journal of Biological Chemistry
@fr
artículu científicu espublizáu en 2010
@ast
im Januar 2010 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2010/01/15)
@sk
vědecký článek publikovaný v roce 2010
@cs
wetenschappelijk artikel (gepubliceerd op 2010/01/15)
@nl
наукова стаття, опублікована в січні 2010
@uk
name
GLP-1 mediates antiapoptotic e ...... ation in pancreatic beta-cells
@ast
GLP-1 mediates antiapoptotic e ...... ation in pancreatic beta-cells
@en
GLP-1 mediates antiapoptotic e ...... ation in pancreatic beta-cells
@nl
type
label
GLP-1 mediates antiapoptotic e ...... ation in pancreatic beta-cells
@ast
GLP-1 mediates antiapoptotic e ...... ation in pancreatic beta-cells
@en
GLP-1 mediates antiapoptotic e ...... ation in pancreatic beta-cells
@nl
prefLabel
GLP-1 mediates antiapoptotic e ...... ation in pancreatic beta-cells
@ast
GLP-1 mediates antiapoptotic e ...... ation in pancreatic beta-cells
@en
GLP-1 mediates antiapoptotic e ...... ation in pancreatic beta-cells
@nl
P2093
P2860
P921
P3181
P356
P1476
GLP-1 mediates antiapoptotic e ...... ation in pancreatic beta-cells
@en
P2093
Christine Longuet
Christophe Broca
Elodie Varin
Gyslaine Bertrand
Julie Quoyer
Nathalie Linck
Safia Costes
Stéphane Dalle
P2860
P304
P3181
P356
10.1074/JBC.M109.067207
P407
P577
2010-01-15T00:00:00Z