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Mineralocorticoid receptor knockout mice: pathophysiology of Na+ metabolism

Mineralocorticoid receptor knockout mice: pathophysiology of Na+ metabolism

http://www.wikidata.org/entity/Q28506467

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Evidence for modulation of pericryptal sheath myofibroblasts in rat descending colon by transforming growth factor beta and angiotensin II The role of renin-angiotensin aldosterone system related micro-ribonucleic acids in hypertension Inhibition of ENaC by endothelin-1 Regulation of αENaC transcription Organization of the ENaC-regulatory machinery Glucocorticoid signaling in the heart: A cardiomyocyte perspective Regulation and physiological roles of serum- and glucocorticoid-induced protein kinase isoforms Diethylstilbestrol regulates trophoblast stem cell differentiation as a ligand of orphan nuclear receptor ERR beta Collecting duct-specific knockout of endothelin-1 causes hypertension and sodium retention Kidney function in mice lacking aldosterone Interactions between 11beta-hydroxysteroid dehydrogenase and COX-2 in kidney Compensation of proximal tubule malabsorption in AQP1-deficient mice without TGF-mediated reduction of GFR Cochlear distribution of Na,K-ATPase and corticosteroid receptors in two mouse strains with congenital hearing disorders Af17 deficiency increases sodium excretion and decreases blood pressure Scaffold protein connector enhancer of kinase suppressor of Ras isoform 3 (CNK3) coordinates assembly of a multiprotein epithelial sodium channel (ENaC)-regulatory complex Loss of the limbic mineralocorticoid receptor impairs behavioral plasticity.The role of glucocorticoids for spiral ganglion neuron survival.Hypothalamic-pituitary-adrenal axis dysregulation and behavioral analysis of mouse mutants with altered glucocorticoid or mineralocorticoid receptor function Direct regulation of blood pressure by smooth muscle cell mineralocorticoid receptors Glucocorticoid regulation of lung development: lessons learned from conditional GR knockout mice Silencing of the mineralocorticoid receptor by ribonucleic acid interference in transgenic rats disrupts endocrine homeostasis.HuR-Dependent Editing of a New Mineralocorticoid Receptor Splice Variant Reveals an Osmoregulatory Loop for Sodium Homeostasis Efficacy and safety of zoledronic acid in the treatment of glucocorticoid-induced osteoporosis.Osmotic stress regulates mineralocorticoid receptor expression in a novel aldosterone-sensitive cortical collecting duct cell line.Reversible cardiac fibrosis and heart failure induced by conditional expression of an antisense mRNA of the mineralocorticoid receptor in cardiomyocytes.Crystal structure of the mineralocorticoid receptor DNA binding domain in complex with DNA.Role of epithelial sodium channels and their regulators in hypertension.Impaired renal Na(+) retention in the sgk1-knockout mouse.The glucocorticoid receptor in the distal nephron is not necessary for the development or maintenance of dexamethasone-induced hypertension Sodium and calcium transport pathways along the mammalian distal nephron: from rabbit to human.Sodium transport deficiency and sodium balance in gene-targeted mice.Expression and role of serum and glucocorticoid-regulated kinase 2 in the regulation of Na+/H+ exchanger 3 in the mammalian kidney.Blunted hypertensive effect of combined fructose and high-salt diet in gene-targeted mice lacking functional serum- and glucocorticoid-inducible kinase SGK1.Electrolyte transport in the mammalian colon: mechanisms and implications for disease.UT-A urea transporter promoter, UT-Aalpha, targets principal cells of the renal inner medullary collecting duct.Mineralocorticoid receptors in vascular disease: connecting molecular pathways to clinical implications.Abnormal regulation of ENaC: syndromes of salt retention and salt wasting by the collecting duct.Concerted action of ENaC, Nedd4-2, and Sgk1 in transepithelial Na(+) transport.Aldosterone synthase inhibition: cardiorenal protection in animal disease models and translation of hormonal effects to human subjects.Aldosterone postnatally, but not at birth, is required for optimal induction of renal mineralocorticoid receptor expression and sodium reabsorption.

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P2860

Mineralocorticoid receptor knockout mice: pathophysiology of Na+ metabolism

http://www.wikidata.org/entity/Q28506467

description

1998 թուականի Օգոստոսին հրատարակուած գիտական յօդուած

@hyw

1998 թվականի օգոստոսին հրատարակված գիտական հոդված

@hy

article publié dans les Procee ...... f the United States of America

@fr

artículu científicu espublizáu en 1998

@ast

im August 1998 veröffentlichter wissenschaftlicher Artikel

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scientific journal article

@en

vedecký článok (publikovaný 1998/08/04)

@sk

vědecký článek publikovaný v roce 1998

@cs

wetenschappelijk artikel (gepubliceerd op 1998/08/04)

@nl

наукова стаття, опублікована в серпні 1998

@uk

name

Mineralocorticoid receptor knockout mice: pathophysiology of Na+ metabolism

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Mineralocorticoid receptor knockout mice: pathophysiology of Na+ metabolism

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Mineralocorticoid receptor knockout mice: pathophysiology of Na+ metabolism

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type

label

Mineralocorticoid receptor knockout mice: pathophysiology of Na+ metabolism

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Mineralocorticoid receptor knockout mice: pathophysiology of Na+ metabolism

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Mineralocorticoid receptor knockout mice: pathophysiology of Na+ metabolism

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prefLabel

Mineralocorticoid receptor knockout mice: pathophysiology of Na+ metabolism

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Mineralocorticoid receptor knockout mice: pathophysiology of Na+ metabolism

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Mineralocorticoid receptor knockout mice: pathophysiology of Na+ metabolism

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PNAS.95.16.9424

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Proceedings of the National Academy of Sciences of the United States of America

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Mineralocorticoid receptor knockout mice: pathophysiology of Na+ metabolism

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G Schütz

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H Watanabe

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J Peters

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P2860

Cloning of human mineralocorticoid receptor complementary DNA: structural and functional kinship with the glucocorticoid receptor

WW domains of Nedd4 bind to the proline-rich PY motifs in the epithelial Na+ channel deleted in Liddle's syndrome

Single-Step Method of RNA Isolation by Acid Guanidinium Thiocyanate–Phenol–Chloroform Extraction

Cloning and tissue distribution of the human 11 beta-hydroxysteroid dehydrogenase type 2 enzyme

Tissue-specific expression of alpha and beta messenger ribonucleic acid isoforms of the human mineralocorticoid receptor in normal and pathological states

Amiloride-sensitive epithelial Na+ channel is made of three homologous subunits

Differentiation-induced gene expression in 3T3-L1 preadipocytes. A second differentially expressed gene encoding stearoyl-CoA desaturase

Mutations in subunits of the epithelial sodium channel cause salt wasting with hyperkalaemic acidosis, pseudohypoaldosteronism type 1

Mineralocorticoid action: target tissue specificity is enzyme, not receptor, mediated

The neuronal mineralocorticoid receptor as a mediator of glucocorticoid response

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9424-9429

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pathophysiology

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