Gremlin-mediated BMP antagonism induces the epithelial-mesenchymal feedback signaling controlling metanephric kidney and limb organogenesis
about
The bone morphogenetic protein antagonist gremlin 1 is overexpressed in human cancers and interacts with YWHAH proteinBone morphogenetic protein-4 inhibitor gremlin is overexpressed in idiopathic pulmonary fibrosisGremlin enhances the determined path to cardiomyogenesisRnf165/Ark2C enhances BMP-Smad signaling to mediate motor axon extensionExome sequencing followed by large-scale genotyping fails to identify single rare variants of large effect in idiopathic generalized epilepsyInhibitors/antagonists of TGF-β system in kidney fibrosisGenetic controls and cellular behaviors in branching morphogenesis of the renal collecting systemRegulation of the ovarian reserve by members of the transforming growth factor beta familyKidney regeneration: common themes from the embryo to the adultThe DAN family: modulators of TGF-β signaling and beyondFstl1 antagonizes BMP signaling and regulates ureter developmentA secreted BMP antagonist, Cer1, fine tunes the spatial organization of the ureteric bud tree during mouse kidney developmentGremlin 1 identifies a skeletal stem cell with bone, cartilage, and reticular stromal potential.Gremlin-1 Overexpression in Mouse Lung Reduces Silica-Induced Lymphocyte Recruitment - A Link to Idiopathic Pulmonary Fibrosis through Negative Correlation with CXCL10 ChemokineDevelopment of the Mammalian KidneyFollistatin-like 1 in vertebrate developmentIsl1Cre reveals a common Bmp pathway in heart and limb developmentSall genes regulate region-specific morphogenesis in the mouse limb by modulating Hox activitiesGenetic evidence that SOST inhibits WNT signaling in the limbHedgehog signaling in pancreas epithelium regulates embryonic organ formation and adult beta-cell functionSix1 regulates Grem1 expression in the metanephric mesenchyme to initiate branching morphogenesisGata3 acts downstream of beta-catenin signaling to prevent ectopic metanephric kidney inductionMouse limb deformity mutations disrupt a global control region within the large regulatory landscape required for Gremlin expressionMsx1 and Msx2 in limb mesenchyme modulate digit number and identityDigit patterning during limb development as a result of the BMP-receptor interactionVertebrate limb development: moving from classical morphogen gradients to an integrated 4-dimensional patterning systemThe transformation suppressor gene Reck is required for postaxial patterning in mouse forelimbs.A new molecular logic for BMP-mediated dorsoventral patterning in the leech HelobdellaThe origin of bmp16, a novel Bmp2/4 relative, retained in teleost fish genomesUterine sensitization-associated gene-1 (USAG-1), a novel BMP antagonist expressed in the kidney, accelerates tubular injury.Kidney development in the absence of Gdnf and Spry1 requires Fgf10.Newly generated cells are increased in hippocampus of adult mice lacking a serine protease inhibitor.Prognostic significance of Gremlin1 (GREM1) promoter CpG island hypermethylation in clear cell renal cell carcinoma.Formins in development: orchestrating body plan origami.Transcriptome analyses based on genetic screens for Pax3 myogenic targets in the mouse embryo.Shh pathway activation is present and required within the vertebrate limb bud apical ectodermal ridge for normal autopod patterningA GREM1 gene variant associates with diabetic nephropathy.Gremlin1 plays a key role in kidney development and renal fibrosisBetaglycan is required for the establishment of nephron endowment in the mouse.Genetic analysis reveals an unexpected role of BMP7 in initiation of ureteric bud outgrowth in mouse embryos.
P2860
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P2860
Gremlin-mediated BMP antagonism induces the epithelial-mesenchymal feedback signaling controlling metanephric kidney and limb organogenesis
description
2004 թուականի Յուլիսին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի հուլիսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2004
@ast
im Juli 2004 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2004/07/01)
@sk
vědecký článek publikovaný v roce 2004
@cs
wetenschappelijk artikel (gepubliceerd op 2004/07/01)
@nl
наукова стаття, опублікована в липні 2004
@uk
مقالة علمية (نشرت في يوليو 2004)
@ar
name
Gremlin-mediated BMP antagonis ...... kidney and limb organogenesis
@ast
Gremlin-mediated BMP antagonis ...... kidney and limb organogenesis
@en
Gremlin-mediated BMP antagonis ...... kidney and limb organogenesis
@nl
type
label
Gremlin-mediated BMP antagonis ...... kidney and limb organogenesis
@ast
Gremlin-mediated BMP antagonis ...... kidney and limb organogenesis
@en
Gremlin-mediated BMP antagonis ...... kidney and limb organogenesis
@nl
prefLabel
Gremlin-mediated BMP antagonis ...... kidney and limb organogenesis
@ast
Gremlin-mediated BMP antagonis ...... kidney and limb organogenesis
@en
Gremlin-mediated BMP antagonis ...... kidney and limb organogenesis
@nl
P50
P3181
P356
P1433
P1476
Gremlin-mediated BMP antagonis ...... kidney and limb organogenesis
@en
P2093
Konstantin Beier
Lia Panman
P304
P3181
P356
10.1242/DEV.01251
P407
P577
2004-07-01T00:00:00Z