Reduced sox9 function promotes heart valve calcification phenotypes in vivo
about
Increased dietary intake of vitamin A promotes aortic valve calcification in vivoCoordinating tissue interactions: Notch signaling in cardiac development and diseaseConserved transcriptional regulatory mechanisms in aortic valve development and diseaseIn vitro models of aortic valve calcification: solidifying a systemInhibitory role of Notch1 in calcific aortic valve diseaseTransforming growth factor Beta2 is required for valve remodeling during heart developmentCollagen XIV is important for growth and structural integrity of the myocardiumMolecular imaging insights into early inflammatory stages of arterial and aortic valve calcification.Sox9 transcriptionally represses Spp1 to prevent matrix mineralization in maturing heart valves and chondrocytesRegulation of human chondrocyte function through direct inhibition of cartilage master regulator SOX9 by microRNA-145 (miRNA-145)Loss of β-catenin promotes chondrogenic differentiation of aortic valve interstitial cellsDifferences in valvular and vascular cell responses to strain in osteogenic media.Mef2c regulates transcription of the extracellular matrix protein cartilage link protein 1 in the developing murine heartMmp15 is a direct target of Snai1 during endothelial to mesenchymal transformation and endocardial cushion development.Altered versican cleavage in ADAMTS5 deficient mice; a novel etiology of myxomatous valve disease.Insufficient versican cleavage and Smad2 phosphorylation results in bicuspid aortic and pulmonary valvesIncreased mitochondrial biogenesis in muscle improves aging phenotypes in the mtDNA mutator mouse.Valvular interstitial cells suppress calcification of valvular endothelial cells.Mesoderm-specific Stat3 deletion affects expression of Sox9 yielding Sox9-dependent phenotypes.Valve Endothelial Cell-Derived Tgfβ1 Signaling Promotes Nuclear Localization of Sox9 in Interstitial Cells Associated With Attenuated Calcification.Interplay between CaSR and PTH1R signaling in skeletal development and osteoanabolism.Visualizing novel concepts of cardiovascular calcification.Osteopontin is a novel downstream target of SOX9 with diagnostic implications for progression of liver fibrosis in humans.Calcific Aortic Valve Disease: Molecular Mechanisms and Therapeutic ApproachesTgfβ-Smad and MAPK signaling mediate scleraxis and proteoglycan expression in heart valves.Abnormal muscle mechanosignaling triggers cardiomyopathy in mice with Marfan syndrome.Molecular and developmental mechanisms of congenital heart valve disease.Pathophysiologic mechanisms of calcific aortic stenosis.Targeted PET/CT imaging of vulnerable atherosclerotic plaques: microcalcification with sodium fluoride and inflammation with fluorodeoxyglucose.The living aortic valve: From molecules to function.Review of molecular and mechanical interactions in the aortic valve and aorta: implications for the shared pathogenesis of aortic valve disease and aortopathy.BMP2 expression in the endocardial lineage is required for AV endocardial cushion maturation and remodeling.Dynamin-Related Protein 1 Inhibition Attenuates Cardiovascular Calcification in the Presence of Oxidative Stress.Mitral valve endothelial cells with osteogenic differentiation potential.Genetic basis of aortic valvular disease.Human interstitial cellular model in therapeutics of heart valve calcification.Endothelial nitric oxide signaling regulates Notch1 in aortic valve disease.Pharmacological Regulation of In Situ Tissue Stem Cells Differentiation for Soft Tissue Calcification Treatment.Altered MicroRNA Expression Is Responsible for the Pro-Osteogenic Phenotype of Interstitial Cells in Calcified Human Aortic Valves.Snai1 is important for avian epicardial cell transformation and motility
P2860
Q24630155-0E1A2F70-1EF8-49F6-9250-E519C10144E9Q26822995-F7E3A020-EEF8-4A56-AD62-A2B93CE04F55Q27014023-A628034C-5D1C-4401-A2B2-14578D7B2793Q27022156-B719C896-2AE0-4D09-9A9C-0EB69E9AC056Q28478035-36C73D11-0F01-46A2-8F77-3F092E74B620Q28505676-88FF7BCE-4D58-491C-B7B7-9E2F134754B1Q28507863-4DCB28CA-7135-48C6-9E0D-453150DE6297Q30474772-22BB9954-4616-4ABC-8B82-F37CFCFBA263Q34064669-870F65B6-E59D-496E-BADC-0A3ADEEEFE2DQ34234586-8C5ED708-C141-4ED5-A9BC-00481E50065CQ34550461-06017CE9-B38B-4C14-9F30-96D5247C7320Q34590497-B35FABC5-AF57-4928-AADD-3AF236AF8102Q34611724-59DEFD4D-8CB4-4E4B-9EA0-6538943DA9FDQ35457031-E7A45E0B-A0F4-461D-8737-2C58C72FA4E5Q35618803-78BA2A58-2BB8-4CC6-840D-6195C4A29647Q35624491-F3DA8BFD-2EC8-4975-B616-8B4EB0C9E8BCQ35909435-1466F07E-1F4F-4272-BB4F-EF01B4FD00CBQ35988417-43512490-ED57-4FAB-B9E6-BDF31C7C8EECQ36271527-42CDA54B-EEAB-4EB7-8084-1F059421762EQ36520549-F0420836-2D5E-4CBF-ABB2-CA3710FE1481Q36600824-E8D57566-01DC-475C-A399-C3D9A9A1DC0FQ36765026-2883F049-F6AF-40C6-8AA0-3F512E38D8E3Q36801010-D1CB551D-3A4D-4CBB-90CF-03AEC5523ABFQ36956234-FD36388C-E01E-41C4-B9B1-61105ACACD7AQ37406574-734931CB-9ED8-4ED0-AF19-37E3FA6C61B3Q37602214-9036E339-2014-417F-ACED-9A218620C1CFQ37871548-D2880DE2-02A1-43FF-BE03-DFD827F8BF98Q37987807-A5C95707-7117-49C2-AB14-4B54E80A4D81Q38100694-FD545CD7-D126-4350-9A2E-EC31C09BA65BQ38233054-19FDDBD9-B049-46CF-A50E-2593348E7AB5Q38269616-1B85A448-7C6D-4A57-A9D1-B072938E7A73Q38633340-757EEE15-BC0F-4785-AD25-B668922C854DQ38728964-83065AFB-5E17-4EB2-93FE-4332968A079AQ38978261-814B1C21-3CDF-4A85-9A1D-8F83ABC1BD3AQ39117737-EB9A7D67-AD9F-4C17-B037-03566E7E0F47Q39325703-4D9AFDF5-8FB3-4DE1-BB78-0E53CEE7A45FQ40748118-64B615B8-D7DA-454A-9A78-43862AC1278AQ40802546-CABB6D2D-CFDD-4587-A7F0-F9FCB0FF9CA6Q41166213-AF9D4FFB-F8D4-4AA4-9054-DA3EB0E0C729Q41266029-F832F270-4EF4-4DB4-8C98-CA22483C15EC
P2860
Reduced sox9 function promotes heart valve calcification phenotypes in vivo
description
2010 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2010 թվականի մարտին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2010
@ast
im März 2010 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2010/03/05)
@sk
vědecký článek publikovaný v roce 2010
@cs
wetenschappelijk artikel (gepubliceerd op 2010/03/05)
@nl
наукова стаття, опублікована в березні 2010
@uk
مقالة علمية (نشرت في 5-3-2010)
@ar
name
Reduced sox9 function promotes heart valve calcification phenotypes in vivo
@ast
Reduced sox9 function promotes heart valve calcification phenotypes in vivo
@en
Reduced sox9 function promotes heart valve calcification phenotypes in vivo
@nl
type
label
Reduced sox9 function promotes heart valve calcification phenotypes in vivo
@ast
Reduced sox9 function promotes heart valve calcification phenotypes in vivo
@en
Reduced sox9 function promotes heart valve calcification phenotypes in vivo
@nl
prefLabel
Reduced sox9 function promotes heart valve calcification phenotypes in vivo
@ast
Reduced sox9 function promotes heart valve calcification phenotypes in vivo
@en
Reduced sox9 function promotes heart valve calcification phenotypes in vivo
@nl
P2093
P2860
P1433
P1476
Reduced sox9 function promotes heart valve calcification phenotypes in vivo
@en
P2093
Agata K. Levay
Devin B. Gillaspie
Jacqueline D. Peacock
Joy Lincoln
P2860
P304
P356
10.1161/CIRCRESAHA.109.213702
P577
2010-03-05T00:00:00Z