POU domain factor Brn-3b is essential for retinal ganglion cell differentiation and survival but not for initial cell fate specification
about
Diversity, phylogeny and expression patterns of Pou and Six homeodomain transcription factors in hydrozoan jellyfish Craspedacusta sowerbyiRIT2, a neuron-specific small guanosine triphosphatase, is expressed in retinal neuronal cells and its promoter is modulated by the POU4 transcription factorsBrn3a is a transcriptional regulator of soma size, target field innervation and axon pathfinding of inner ear sensory neuronsRequirement for math5 in the development of retinal ganglion cellsCardiac expression of Brn-3a and Brn-3b POU transcription factors and regulation of Hsp27 gene expressionA comprehensive negative regulatory program controlled by Brn3b to ensure ganglion cell specification from multipotential retinal precursorsGamma-synuclein as a marker of retinal ganglion cellsThe Optimedin gene is a downstream target of Pax6Conditional deletion of activating protein 2alpha (AP-2alpha) in the developing retina demonstrates non-cell-autonomous roles for AP-2alpha in optic cup developmentISL1 and BRN3B co-regulate the differentiation of murine retinal ganglion cellsRequirement for Bhlhb5 in the specification of amacrine and cone bipolar subtypes in mouse retinaThe Wilms' tumor gene Wt1 is required for normal development of the retinaTwo transcription factors, Pou4f2 and Isl1, are sufficient to specify the retinal ganglion cell fateBrn-3b enhances the pro-apoptotic effects of p53 but not its induction of cell cycle arrest by cooperating in trans-activation of bax expressionIsl1 and Pou4f2 form a complex to regulate target genes in developing retinal ganglion cellsComparative expression analysis of POU4F1, POU4F2 and ISL1 in developing mouse cochleovestibular ganglion neurons.LMO4 functions as a negative regulator of sensory organ formation in the mammalian cochleaThe expression of retinal cell markers in human retinal pigment epithelial cells and their augmentation by the synthetic retinoid fenretinide.Distinct roles of transcription factors brn3a and brn3b in controlling the development, morphology, and function of retinal ganglion cells.Islet-1 controls the differentiation of retinal bipolar and cholinergic amacrine cellsGene expression in the developing mouse retina by EST sequencing and microarray analysisSm22α transcription occurs at the early onset of the cardiovascular system and the intron 1 is dispensable for its transcription in smooth muscle cells during mouse development.Gfi1-Cre knock-in mouse line: A tool for inner ear hair cell-specific gene deletion.Generation and characterization of Atoh1-Cre knock-in mouse line.Eomesodermin, a target gene of Pou4f2, is required for retinal ganglion cell and optic nerve development in the mouse.The Ath5 proneural genes function upstream of Brn3 POU domain transcription factor genes to promote retinal ganglion cell development.Vertebrate neural cell-fate determination: lessons from the retina.T-box transcription regulator Tbr2 is essential for the formation and maintenance of Opn4/melanopsin-expressing intrinsically photosensitive retinal ganglion cellsTranscriptome of Atoh7 retinal progenitor cells identifies new Atoh7-dependent regulatory genes for retinal ganglion cell formation.Development of the retina and optic pathway.Nerve fiber layer thinning lags retinal ganglion cell density following crush axonopathyNeuronal transcriptional repressor REST suppresses an Atoh7-independent program for initiating retinal ganglion cell developmentGenetic interactions between Brn3 transcription factors in retinal ganglion cell type specification.Mouse retinal development: a dark horse model for systems biology researchNeuroprotective effects of transcription factor Brn3b in an ocular hypertension rat model of glaucomaBirth of cone bipolar cells, but not rod bipolar cells, is associated with existing RGCsPhotoentrainment and pupillary light reflex are mediated by distinct populations of ipRGCs.Pou4f1 and pou4f2 are dispensable for the long-term survival of adult retinal ganglion cells in mice.Protein profiling of human nonpigmented ciliary epithelium cell secretome: the differentiation factors characterization for retinal ganglion cell lineStructural correlation between the nerve fiber layer and retinal ganglion cell loss in mice with targeted disruption of the Brn3b gene.
P2860
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P2860
POU domain factor Brn-3b is essential for retinal ganglion cell differentiation and survival but not for initial cell fate specification
description
1999 թուականի Յունիսին հրատարակուած գիտական յօդուած
@hyw
1999 թվականի հունիսին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 1999
@ast
im Juni 1999 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 1999/06/15)
@sk
vědecký článek publikovaný v roce 1999
@cs
wetenschappelijk artikel (gepubliceerd op 1999/06/15)
@nl
наукова стаття, опублікована в червні 1999
@uk
научни чланак (објављен 1999/06/15)
@sr
name
POU domain factor Brn-3b is es ...... nitial cell fate specification
@ast
POU domain factor Brn-3b is es ...... nitial cell fate specification
@en
POU domain factor Brn-3b is es ...... nitial cell fate specification
@nl
type
label
POU domain factor Brn-3b is es ...... nitial cell fate specification
@ast
POU domain factor Brn-3b is es ...... nitial cell fate specification
@en
POU domain factor Brn-3b is es ...... nitial cell fate specification
@nl
prefLabel
POU domain factor Brn-3b is es ...... nitial cell fate specification
@ast
POU domain factor Brn-3b is es ...... nitial cell fate specification
@en
POU domain factor Brn-3b is es ...... nitial cell fate specification
@nl
P2093
P3181
P356
P1476
POU domain factor Brn-3b is es ...... nitial cell fate specification
@en
P2093
P304
P3181
P356
10.1006/DBIO.1999.9280
P407
P577
1999-06-15T00:00:00Z