SIK3 is essential for chondrocyte hypertrophy during skeletal development in mice
about
A pathway to bone: signaling molecules and transcription factors involved in chondrocyte development and maturationSalt-inducible kinase 3 is a novel mitotic regulator and a target for enhancing antimitotic therapeutic-mediated cell death.Salt-inducible kinase 3, SIK3, is a new gene associated with hearing.Involvement of SIK3 in glucose and lipid homeostasis in mice.Role of salt-inducible kinase 1 in the activation of MEF2-dependent transcription by BDNFSalt-inducible Kinase 3 Signaling Is Important for the Gluconeogenic Programs in Mouse Hepatocytes.Histone Deacetylases in Bone Development and Skeletal Disorders.Skeletal muscle salt inducible kinase 1 promotes insulin resistance in obesity.Regulation of SIK1 abundance and stability is critical for myogenesisDevelopment of the endochondral skeletonPterosin B prevents chondrocyte hypertrophy and osteoarthritis in mice by inhibiting Sik3.SIKs control osteocyte responses to parathyroid hormoneMicroRNA-140 Provides Robustness to the Regulation of Hypertrophic Chondrocyte Differentiation by the PTHrP-HDAC4 Pathway.Understanding developmental mechanisms in the context of osteoarthritis.Overview of skeletal development.The chondrocytic journey in endochondral bone growth and skeletal dysplasia.Chondrocyte hypertrophy in skeletal development, growth, and disease.Inhibition of SIK2 and SIK3 during differentiation enhances the anti-inflammatory phenotype of macrophagesThe tumor suppressor kinase LKB1 activates the downstream kinases SIK2 and SIK3 to stimulate nuclear export of class IIa histone deacetylases.Salt-inducible kinases (SIK) inhibition reduces RANKL-induced osteoclastogenesis.Salt-inducible kinase 3 regulates the mammalian circadian clock by destabilizing PER2 protein.Salt-inducible kinase induces cytoplasmic histone deacetylase 4 to promote vascular calcification.LKB1, Salt-Inducible Kinases, and MEF2C Are Linked Dependencies in Acute Myeloid Leukemia.
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P2860
SIK3 is essential for chondrocyte hypertrophy during skeletal development in mice
description
2012 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2012 թվականի մարտին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2012
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im März 2012 veröffentlichter wissenschaftlicher Artikel
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scientific journal article
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vedecký článok (publikovaný 2012/03/01)
@sk
vědecký článek publikovaný v roce 2012
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wetenschappelijk artikel (gepubliceerd op 2012/03/01)
@nl
наукова стаття, опублікована в березні 2012
@uk
مقالة علمية (نشرت في مارس 2012)
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name
SIK3 is essential for chondrocyte hypertrophy during skeletal development in mice
@ast
SIK3 is essential for chondrocyte hypertrophy during skeletal development in mice
@en
SIK3 is essential for chondrocyte hypertrophy during skeletal development in mice
@nl
type
label
SIK3 is essential for chondrocyte hypertrophy during skeletal development in mice
@ast
SIK3 is essential for chondrocyte hypertrophy during skeletal development in mice
@en
SIK3 is essential for chondrocyte hypertrophy during skeletal development in mice
@nl
prefLabel
SIK3 is essential for chondrocyte hypertrophy during skeletal development in mice
@ast
SIK3 is essential for chondrocyte hypertrophy during skeletal development in mice
@en
SIK3 is essential for chondrocyte hypertrophy during skeletal development in mice
@nl
P2093
P3181
P356
P1433
P1476
SIK3 is essential for chondrocyte hypertrophy during skeletal development in mice
@en
P2093
Daisuke Ikegami
Hideki Yoshikawa
Hiroshi Takemori
Kunihiko Hiramatsu
Shiro Ikegawa
Tatsuya Uebi
P304
P3181
P356
10.1242/DEV.072652
P407
P577
2012-02-08T00:00:00Z