Regulation of retinoic acid distribution is required for proximodistal patterning and outgrowth of the developing mouse limb
about
Phenotypic and functional consequences of haploinsufficiency of genes from exocyst and retinoic acid pathway due to a recurrent microdeletion of 2p13.2Craniosynostosis and multiple skeletal anomalies in humans and zebrafish result from a defect in the localized degradation of retinoic acidRetinoic acid synthesis and signaling during early organogenesisRetinoic acid regulation of the somitogenesis clockRetinoic acid promotes limb induction through effects on body axis extension but is unnecessary for limb patterningRole of Retinoic Acid-Metabolizing Cytochrome P450s, CYP26, in Inflammation and CancerLeukocyte homing, fate, and function are controlled by retinoic acidMechanisms of retinoic acid signalling and its roles in organ and limb developmentThe making of differences between fins and limbsCanonical Notch signaling plays an instructive role in auditory supporting cell development.Retinaldehyde dehydrogenase 2 is down-regulated during duodenal atresia formation in Fgfr2IIIb-/- miceDynamic expression of retinoic acid-synthesizing and -metabolizing enzymes in the developing mouse inner ear.The retinoic acid-metabolizing enzyme Cyp26b1 regulates CD4 T cell differentiation and functionLineage-specific duplication of amphioxus retinoic acid degrading enzymes (CYP26) resulted in sub-functionalization of patterning and homeostatic rolesDownstream genes of Pax6 revealed by comprehensive transcriptome profiling in the developing rat hindbrainIncreased retinoic acid levels through ablation of Cyp26b1 determine the processes of embryonic skin barrier formation and peridermal developmentAntagonistic regulation of Cyp26b1 by transcription factors SOX9/SF1 and FOXL2 during gonadal development in miceThe retinaldehyde reductase DHRS3 is essential for preventing the formation of excess retinoic acid during embryonic developmentShifting boundaries of retinoic acid activity control hindbrain segmental gene expressionApplication of synthetic photostable retinoids induces novel limb and facial phenotypes during chick embryogenesis in vivoFull regeneration of the tribasal Polypterus finVertebrate limb development: moving from classical morphogen gradients to an integrated 4-dimensional patterning systemRetinoic acid actions through mammalian nuclear receptors.Visualization of retinoic acid signaling in transgenic axolotls during limb development and regenerationComplex regulation of cyp26a1 creates a robust retinoic acid gradient in the zebrafish embryo.Data-driven modelling of a gene regulatory network for cell fate decisions in the growing limb bud.Cyp26b1 expression in murine Sertoli cells is required to maintain male germ cells in an undifferentiated state during embryogenesis.Wnt/beta-catenin and retinoic acid receptor signaling pathways interact to regulate chondrocyte function and matrix turnover.A comparison of the roles of peroxisome proliferator-activated receptor and retinoic acid receptor on CYP26 regulation.Expression and functional characterization of cytochrome P450 26A1, a retinoic acid hydroxylaseCyp26b1 regulates retinoic acid-dependent signals in T cells and its expression is inhibited by transforming growth factor-β.The relative importance of CYP26A1 in hepatic clearance of all-trans retinoic acid.Retinoic acid activates two pathways required for meiosis in mice.The Meis homeoprotein regulates the axolotl Prod 1 promoter during limb regeneration.Therapeutic potential of the inhibition of the retinoic acid hydroxylases CYP26A1 and CYP26B1 by xenobiotics.Rdh10 mutants deficient in limb field retinoic acid signaling exhibit normal limb patterning but display interdigital webbing.SHH propagates distal limb bud development by enhancing CYP26B1-mediated retinoic acid clearance via AER-FGF signalling.Vitamin a is a negative regulator of osteoblast mineralization.Alcohol and aldehyde dehydrogenases: retinoid metabolic effects in mouse knockout modelsRetinoic acid-independent expression of Meis2 during autopod patterning in the developing bat and mouse limb
P2860
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P2860
Regulation of retinoic acid distribution is required for proximodistal patterning and outgrowth of the developing mouse limb
description
2004 թուականի Մարտին հրատարակուած գիտական յօդուած
@hyw
2004 թվականի մարտին հրատարակված գիտական հոդված
@hy
artículu científicu espublizáu en 2004
@ast
im März 2004 veröffentlichter wissenschaftlicher Artikel
@de
scientific journal article
@en
vedecký článok (publikovaný 2004/03/01)
@sk
vědecký článek publikovaný v roce 2004
@cs
wetenschappelijk artikel (gepubliceerd op 2004/03/01)
@nl
наукова стаття, опублікована в березні 2004
@uk
مقالة علمية (نشرت في مارس 2004)
@ar
name
Regulation of retinoic acid di ...... h of the developing mouse limb
@ast
Regulation of retinoic acid di ...... h of the developing mouse limb
@en
Regulation of retinoic acid di ...... h of the developing mouse limb
@nl
type
label
Regulation of retinoic acid di ...... h of the developing mouse limb
@ast
Regulation of retinoic acid di ...... h of the developing mouse limb
@en
Regulation of retinoic acid di ...... h of the developing mouse limb
@nl
prefLabel
Regulation of retinoic acid di ...... h of the developing mouse limb
@ast
Regulation of retinoic acid di ...... h of the developing mouse limb
@en
Regulation of retinoic acid di ...... h of the developing mouse limb
@nl
P2093
P1433
P1476
Regulation of retinoic acid di ...... h of the developing mouse limb
@en
P2093
Hiroshi Hamada
Jinsuke Nishino
Kenta Yashiro
Kimiyo Yamashita
Masayuki Uehara
Misae Nishijima
Xianling Zhao
Yasuo Sakai
Yukio Saijoh
P304
P356
10.1016/S1534-5807(04)00062-0
P407
P577
2004-03-01T00:00:00Z